Versican Plus Pi/L4R Lyophilisate and Suspension for Suspension for Injection for Dogs
Active ingredients: Canine parainfluenza virus, Leptospira interrogans serogroup Australis, Leptospira interrogans serogroup Canicola, Leptospira interrogans serogroup Icterohaemorrhagiae, Leptospira kirschneri serogroup Grippotyphosa, Rabies virus
Form
Injection
Species
Manufacturer
Zoetis UK Limited
VMD MA No.
42058/5087
What it's used for
Active immunisation of dogs from 8–9 weeks of age: - to prevent clinical signs (nasal and ocular discharge) and reduce viral excretion caused by canine par...
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Prescription required
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Versican Plus Pi/L4R Lyophilisate and Suspension for Suspension for Injection for Dogs — SPC Details
Source: VMD Summary of Product Characteristics (SPC). Last updated 26 Mar 2026.
- to prevent clinical signs (nasal and ocular discharge) and reduce viral excretion
caused by canine parainfluenza virus,
- to prevent clinical signs, infection and urinary excretion caused by L.
interrogans serogroup Australis serovar Bratislava,
- to prevent clinical signs and urinary excretion and reduce infection caused by L.
interrogans serogroup Canicola serovar Canicola and L. interrogans serogroup
Icterohaemorrhagiae serovar Icterohaemorrhagiae,
- to prevent clinical signs and reduce infection and urinary excretion caused by L.
kirschneri serogroup Grippotyphosa serovar Grippotyphosa and
- to prevent mortality, clinical signs and infection caused by rabies virus.
Onset of immunity:
- 2 weeks after a single vaccination from 12 weeks of age for rabies,
- 3 weeks after completion of the primary course for CPiV and
- 4 weeks after completion of the primary course for components.
Duration of immunity:
At least three years following the primary vaccination course for rabies. At least one
year following the primary vaccination course for canine parainfluenza virus and
Leptospira components. Duration of immunity for rabies was demonstrated after one
vaccination at 12 weeks of age.
Common
(1 to 10 animals / 100 animals
treated):
injection site swelling
Rare
(1 to 10 animals / 10,000
animals treated):
hypersensitivity reaction
(anaphylaxis,
angioedema, circulatory shock, collapse,
diarrhoea, dyspnoea, vomiting)
anorexia, decreased activity
Very rare
(<1 animal / 10,000 animals
treated, including isolated
reports):
hyperthermia, lethargy, malaise
immune mediated haemolytic anaemia, immune
mediated haemolytic thrombocytopenia,
immune mediated polyarthritis
A transient swelling (up to 5 cm) which can be painful, warm or reddened. Any such
swelling will either have spontaneously resolved or be greatly diminished by 14 days
after vaccination.
If a hypersensitivity reaction occurs, appropriate treatment should be administered
without delay. Such reactions may evolve to a more severe condition which may be
life-threatening.
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder or its local representative or the national
competent authority via the national reporting system. See also the last section of the
package leaflet for respective contact details.
Immunocompetence of the animal may be compromised by a variety of factors
including poor health, nutritional status, genetic factors, concurrent drug therapy and
stress.
Vaccinate healthy animals only.
i) Special precautions for use in animals
Do not use in animals that are showing signs of rabies or that are suspected of being
infected with rabies virus.
The live attenuated virus vaccine strain CPiV may be shed by vaccinated dogs
following vaccination. However, due to the low pathogenicity of the strain, it is not
necessary to keep vaccinated dogs separated from non-vaccinated dogs.
Revised: August 2023
AN: 01466/2022
ii) Special precautions to be taken by the person administering the veterinary
medicinal product to animals
In case of accidental self-injection, seek medical advice immediately and show the
package leaflet or the label to the physician.
Special precautions for the protection of the environment:
Not applicable.
iii) Other precautions
Not applicable.
any other veterinary medicinal product. A decision to use this vaccine before or after
any other veterinary medicinal product therefore needs to be made on a case by
case basis.
Do not freeze.
Protect from light.
Revised: August 2023
AN: 01466/2022
Suspension (inactivated):
Leptospira interrogans serogroup Icterohaemorrhagiae
serovar Icterohaemorrhagiae strain MSLB 1089 ALR** titre ≥ 1:51
Leptospira interrogans serogroup Canicola
serovar Canicola, strain MSLB 1090 ALR** titre ≥ 1:51
Leptospira kirschneri
serovar Grippotyphosa, strain MSLB 1091 ALR** titre ≥ 1:40
Leptospira interrogans serogroup Australis
serovar Bratislava, strain MSLB 1088 ALR** titre ≥ 1:51
Rabies virus, strain SAD Vnukovo-32 5 IU***
* Tissue culture infectious dose 50%.
** Antibody micro agglutination-lytic reaction.
*** International units.
Adjuvant:
Aluminium hydroxide 1.8 – 2.2 mg.
For the full list of excipients, see section
This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.
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Related Conditions
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