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POM-V Prescription Required Companion Animal

Versican Plus DHPPi/L4R lyophilisate and suspension for suspension for injection for dogs

Active ingredients: Canine adenovirus, Canine distemper virus, Canine parainfluenza virus, Canine parvovirus, Leptospira interrogans serogroup Australis, Leptospira interrogans serogroup Canicola, Leptospira interrogans serogroup Icterohaemorrhagiae, Leptospira kirschneri serogroup Grippotyphosa, Rabies virus

Form

Injection

Species

Dogs

Manufacturer

Zoetis Belgium

VMD MA No.

EU/2/14/163/001-002

What it's used for

Duration of immunity: at least one year after the second injection of the primary vaccination course for all strains. Current available challenge and serol...

Full indications, dosage and side effects ↓
View official SPC (PDF)

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Prescription required

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Clinical information

Versican Plus DHPPi/L4R lyophilisate and suspension for suspension for injection for dogs — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

Duration of immunity: at least one year after the second injection of the primary
vaccination course for all strains.
Current available challenge and serological data show that protection for distemper virus,
adenovirus and parvovirus* lasts for 2 years after primary vaccination course followed by
a first annual booster. Any decision to adapt the vaccination schedule of this veterinary
medicinal product needs to be made on a case by case basis, taking into account the
vaccination history of the dog and the epidemiological context.
*Protection has been demonstrated against canine parvovirus type 2a, 2b and 2c either
by challenge (type 2b) or serology (type 2a and 2c).
Shake well before use. The entire contents of the reconstituted vial should be
administered as a single dose. The reconstituted contents shall be an opalescent yellow
to orange suspension.
Inject a 1-ml dose subcutaneously according to the following schedule:
Primary vaccination
Two injections separated by an interval of 4 weeks from 7 weeks of age.
When administered with Boehringer Ingelheim's vaccines containing rabies, the
minimum age for vaccination is 12 weeks of age.
In cases where high levels of maternally derived antibodies are suspected by the
veterinarian and the primary vaccination course was completed before 16 weeks of age,
a third injection using a Boehringer Ingelheim vaccine containing Distemper, Adenovirus
and Parvovirus is recommended from 16 weeks of age, at least 3 weeks after the second
injection.
Revaccination: Administer one dose 12 months after completion of the primary
vaccination course. Dogs should be revaccinated with a single booster dose on an
annual basis.
None.
Dogs:
Common
(1 to 10 animals / 100 animals treated):
Injection site swelling
, injection site
pruritus,
injection site pain.
Lethargy
.
Emesis
.
Uncommon
(1 to 10 animals / 1,000 animals treated):
Anorexia, polydipsia, hyperthermia.
Diarrhoea.
Muscle tremor.
Muscle weakness.
Injection site warmth, injection site
lesions
.
Rare
(1 to 10 animals / 10,000 animals treated):
Hypersensitivity reaction (facial oedema,
anaphylactic shock, urticaria)
.
Slight (≤ 2 cm), immediately after injection. It usually regresses within 1-6 days.
Transient.
Cutaneous.
Some of which are life-threatening. Appropriate symptomatic treatment should promptly
be provided.
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder or the national competent authority via the
national reporting system. See the package leaflet for respective contact details.
None.

Special precautions for safe use in the target species:
Vaccinate healthy animals only.
Apply usual aseptic procedures.
After vaccination, the live CAV-2 and CPV vaccine strains can transiently be shed
without adverse consequence for in-contact animals.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals:
In case of accidental self-injection, seek medical advice immediately and show the
package leaflet or the label to the physician.
Special precautions for the protection of the environment:
Not applicable.
Other precautions:
Safety and efficacy data are available which demonstrate that this vaccine can be
administered with Eurican LR, Eurican L, Eurican Lmulti or Eurican L4 vaccines (used
as solvent) where available.
Safety and efficacy data are available which demonstrate that this vaccine can be
administered on the same day but not mixed with Rabisin if the vaccine has been
reconstituted with Eurican L, Eurican Lmulti or Eurican L4.
When administered with Boehringer Ingelheim's vaccines containing rabies, the
minimum age for vaccination is 12 weeks of age.
When administered reconstituted with the Eurican LR vaccine a small and transient
nodule (maximum size 1.5 cm) at the injection site may be induced due to the presence
of aluminium hydroxide and a slight swelling (~4 cm) may occur after the injection at
injection site, regressing generally within 1-4 days.
When mixed with the Eurican L4 vaccine a swelling (less than 6 cm) may very commonly
occur at the injection site, disappearing within 8 days, anorexia may commonly occur
and vocalisation, tachycardia and tachypnoea may uncommonly be observed. For
Eurican L4, no safety data in pregnant bitches are available for the additional inactivated
strain, Leptospira Australis.
No information is available on the safety and efficacy of this vaccine when used with any
other veterinary medicinal product except the products mentioned above. A decision to
use this vaccine before or after any other veterinary medicinal product therefore needs to
be made on a case by case basis.
Store and transport refrigerated (2 °C – 8 °C).
Protect from light.
Do not freeze.
Not applicable.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.

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