Uriphex, Oral Solution for Dogs
Active ingredient: Phenylpropanolamine Hydrochloride
Form
Liquid
Species
Manufacturer
Alfasan Nederland B.V.
VMD MA No.
36408/3020
What it's used for
Efficacy has only been demonstrated in ovariohysterectomised bitches.
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They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.
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Prescription required
Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.
Uriphex, Oral Solution for Dogs — SPC Details
Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.
possible.
The recommended dose for the veterinary medicinal product is 1mg/kg bodyweight 3
times daily in the feed, corresponding to 0.1 ml of the veterinary medicinal product / 5
kg bodyweight (i.e., a graduation of the provided syringe for 5 kg), 3 times daily.
The absorption rate is increased if the veterinary medicinal product is administered to
fasted dogs.
AN: 02430/2025Page 4 of 6
behavioural causes of inappropriate urination. Do not use in patients treated with
non-selective monoamine oxidase inhibitors.
Do not use in cases of hypersensitivity to the active substance or to any of the
excipients.
Rare
(1 to 10 animals / 10,000 animals treated):
Diarrhoea
, loose stool, emesis
Lethargy
Very rare
(<1 animal / 10,000 animals treated,
including isolated reports):
Tachycardia
, high blood pressure
(hypertension2), arrhythmia
Proteinuria
Wobbliness, ataxia, seizure
Decreased appetite
Collapse, polydipsia
Aggression, hyperactivity (agitation)
Hypersensitivity
Polyuria
Liquid
Effects of sympathomimetics producing excessive stimulation of the sympathetic
nervous system
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder or the national competent authority via the
national reporting system. See the package leaflet for respective contact details.
AN: 02430/2025Page 2 of 6
Special precautions for safe use in the target species:
Due to the very low doses to be administered, and to avoid any risk of overdose, the
animal must be weighed, and the recommended doses must be respected.
Phenylpropanolamine, a sympathomimetic drug, may affect the cardiovascular
system, especially blood pressure and heart rate, and should be used with caution in
animals with cardiovascular diseases.
Care should be exercised in treating animals with severe renal or hepatic
insufficiency, diabetes mellitus, hyperadrenocorticism, glaucoma, hyperthyroidism or
other metabolic disorders.
In bitches less than 1 year old the possibility of anatomical disorders contributing to
incontinence should be considered prior to treatment.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals:
Phenylpropanolamine hydrochloride is toxic when ingested in higher doses. Adverse
effects may include dizziness, headache, nausea, insomnia or restlessness, and
increased blood pressure.
Accidental ingestion by a child may be fatal.
To avoid accidental ingestion, the veterinary medicinal product must be used and
kept out of the sight and reach of children. Always replace the cap securely after use
and store the syringe and bottle inside the cardboard box at all times.
In case of accidental ingestion, seek medical attention immediately and show the
package leaflet or the label to the physician.
In case of accidental skin contact, wash the contaminated area with soap and water.
Wash hands after handling the veterinary medicinal product.
This veterinary medicinal product may cause eye irritation.
In case of accidental eye contact, rinse the eye with clean water for about 15 minutes
and seek medical advice immediately and show the package leaflet or label to the
physician.
Special precautions for the protection of the environment:
Not applicable.
AN: 02430/2025Page 3 of 6
sympathomimetic drugs, anticholinergic drugs, tricyclic antidepressants or specific
type B monoamine oxidase inhibitors.
Keep the bottles in outer carton in order to protect from light.
This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.
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Related Conditions
Other Products Containing Phenylpropanolamine Hydrochloride
These products share the same active ingredient and may be suitable alternatives. Always consult your vet.
IncoVet, 40.28 mg/ml, Syrup for Dogs
POM-VVetoquinol UK Limited
Proin 15 mg Chewable Tablets for Dogs
POM-VPegasus Laboratories Ireland Limited
Proin 15 mg Chewable Tablets for Dogs
POM-VPegasus Laboratories Ireland Limited
Proin 50 mg Chewable Tablets for Dogs
POM-VPegasus Laboratories Ireland Limited
Proin 50 mg Chewable Tablets for Dogs
POM-VPegasus Laboratories Ireland Limited
Uriphex, Oral Solution for Dogs
POM-VAlfasan Nederland B.V.
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