Proin 50 mg Chewable Tablets for Dogs

In bitches less than 1 year old the possibility of anatomical disorders contributing to
incontinence should be considered prior to treatment.
Do not use the product for the treatment of behavioural causes of inappropriate
urination.

Revised: November 2025
AN: 02313/2025

Special precautions for use in animals
Phenylpropanolamine, a sympathomimetic drug, may affect the cardiovascular
system, especially blood pressure and heart rate, and should be used with caution in
animals with cardiovascular diseases.
Phenylpropanolamine has been shown to increase mean arterial blood pressure
resulting in hypertension over time. Animals administered the product should
therefore be monitored for signs of hypertension, particularly with prolonged use of
the product. Care should be exercised in treating animals with pre-existing heart
disease, renal or hepatic insufficiency, diabetes mellitus, hyperadrenocorticism,
glaucoma, hyperthyroidism or other metabolic disorders that may predispose to
hypertension.
Instances of dogs chewing through closed bottles and eating the bottle contents have
been reported. Store the product securely out of reach of dogs and other pets in
order to prevent access and possible overdose. In case of overdose, consult a
veterinarian (See section 4.10).
Special precautions to be taken by the person administering the veterinary medicinal
product to animals
Phenylpropanolamine hydrochloride is toxic when overdoses are ingested. Adverse
effects may include dizziness, headache, nausea, insomnia or restlessness, and
increased blood pressure. High overdose may be fatal, especially in children.
People with known hypersensitivity to phenylpropanolamine or any of the excipients
should avoid contact with the veterinary medicinal product.
To avoid accidental ingestion, the product must be used out of sight of children and
stored out of sight and reach of children. Always replace unused tablets back into
container and replace the cap securely after use.
In case of accidental ingestion, seek medical advice immediately and show the
package leaflet or the label to the physician.
This product can cause skin-irritation. Avoid prolonged exposure to product. Wash
hands after use.
This product can cause eye-irritation. In the event of accidental eye contact, rinse
immediately with plenty of water and seek medical attention if irritation occurs.