POM-V Prescription Required

Tylolab Tartrate 200,000 IU/ml Solution for Injection

Active ingredient: Tylosin Tartrate

Form

Injection

Species

Cattle Pigs

Manufacturer

Labiana Life Sciences SA

VMD MA No.

32112/3001

What it's used for

• For the treatment of foot infections caused by Fusobacterium necrophorum. Pigs: • For the treatment of respiratory infections caused by Pasteurella multo...

Full indications, dosage and side effects ↓

View official SPC (PDF)

The prescription itself has a price. See what practices near you charge for a consultation and the written prescription fee.

Paying less for Tylosin Tartrate

1

Ask your vet for a written prescription

They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.
2

Fill it at a registered online retailer

The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

Your prescription rights → VMD register of retailers →

Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Tylolab Tartrate 200,000 IU/ml Solution for Injection — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

• For the treatment of foot infections caused by Fusobacterium
necrophorum.
Pigs:
• For the treatment of respiratory infections caused by Pasteurella
multocida or Mycoplasma hyopneumoniae.
• For the treatment of mycoplasmal arthritis caused by Mycoplasma
hyosynoviae

Revised February 2025

Cattle: 10,000-20,000 UI of tylosin tartrate/kg bodyweight per day (equivalent
to 0.5-1 ml of the veterinary medicinal product/10 kg bodyweight /day) during
5 consecutive days.
Pigs: 10,000-20,000 UI of tylosin tartrate/kg bodyweight per day (equivalent to
0.5-1 ml of the veterinary medicinal product/10 kg bodyweight /day) during 5
consecutive days.
To ensure the correct dosage, bodyweight should be determined as
accurately as possible to avoid under dosing.
The following maximum volumes should not be exceeded per injection site:
Pigs: 5 ml
Cattle: 25 ml
Provide adequate spacing between injection sites when multiple points of
treatment are necessary. Give a light massage of the injection site.
The cap may be safely punctured up to 34 times for 100 ml vials and 84 times
for the 250 ml vials.

Do not use in cases of hypersensitivity to the active substance, other
macrolides or to any of the excipients.
Do not use in animals with renal and /or liver failure.
Do not administer to horses or other equines in which injection of tylosin may
be fatal.
Do not use in suspected cases of cross-resistance to other macrolides

Cattle and pigs:
Common
(1 to 10 animals / 100
animals treated):
Injection site reactions
with necrosis and
hemorrhage.
Very rare
(<1 animal / 10,000 animals
treated, including isolated
reports):
Allergic reactions, anaphylactic shock and
death.
In cattle there has been increased pulse rate,
tachypnea and swollen vulva
In pigs, vulvar oedema and rectal oedema,
rectal prolapse, diarrhea, erythema and
general pruritus in all the skin
1-can persist for up to 21 days following administration
Reporting adverse events is important. It allows continuous safety monitoring
of a veterinary medicinal product. Reports should be sent, preferably via a
veterinarian, to either the marketing authorisation holder or its local
representative or the national competent authority via the national reporting
system. See also the last section of the package leaflet for respective contact
details.

None.

Special precautions for safe use in the target species:
Cross-resistance has been shown between tylosin and other macrolides or
lincosamides. Use of the veterinary medicinal product should be carefully
considered when susceptibility testing has shown resistance to macrolides or
lincosamides because its effectiveness may be reduced.
Use of the veterinary medicinal product should be based on identification and
susceptibility testing of the target pathogen(s). If this is not possible, therapy
should be based on epidemiological information and knowledge of susceptibility
of the target pathogens at farm level, or at local/regional level.
Use of the veterinary medicinal product should be in accordance with official,
national and regional antimicrobial policies.

An antibiotic with a lower risk of antimicrobial resistance selection (lower AMEG
category) should be used for first line treatment where susceptibility testing
suggests the likely efficacy of this approach
Special precautions to be taken by the person administering the veterinary
medicinal product to animals:
Macrolides, such as tylosin, can cause hypersensitivity (allergy) following
injection, inhalation, ingestion or contact with skin or eyes. Hypersensitivity to
tylosin may lead to cross- reactions with other macrolides and vice versa.
Sodium citrate, benzyl alcohol and propylene glycol can also cause
hypersensitivity reactions. Allergic reactions to these substances may
occasionally be serious and therefore direct contact should be avoided. Do not
handle the medication if you are allergic to any of the veterinary medicinal
product ingredients
If you develop symptoms following exposure such as skin rash, seek medical
advice and show the package leaflet or the label to the physician. Swelling of
the face, lips or eyes or difficulty with breathing are more serious symptoms and
require urgent medical attention.
The veterinary medicinal product may cause irritation to the eyes and skin.

Revised February 2025
Avoid contact with eyes and skin. If this occurs, wash the area thoroughly with
water.
Care must be taken to avoid accidental self-injection. In case of accidental self-
injection, seek medical advice immediately and show the package leaflet or the
label to the physician.
Do not smoke, eat or drink while handling the medication.
Wash hands after use.

interaction
Concurrent use of florfenicol, lincosamides and other macrolide antibacterials
that have a similar action to tylosin, interacting by competing for binding to the
50S subunit, is not recommended.

Revised February 2025

Store in a refrigerator (+2ºC to +8ºC).

Pigs: Meat and offal: 21 days.
Cattle: Meat and offal: 33 days.
Milk: 5 days (120 hours).

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.