POM-V Prescription Required

Tylan Soluble Powder for Oral Solution

Active ingredient: Tylosin Tartrate

Form

Liquid

Species

Cattle Chickens Pigs Turkeys

Manufacturer

Elanco GmbH

VMD MA No.

52127/3047

What it's used for

also proved useful in reducing the level of infection following stress associated with live vaccination. As an aid in the control of outbreaks of necrotic...

Full indications, dosage and side effects ↓

View official SPC (PDF)

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Paying less for Tylosin Tartrate

1

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They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.
2

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The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

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Prescription required

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Clinical information

Tylan Soluble Powder for Oral Solution — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

also proved useful in reducing the level of infection following stress associated
with live vaccination.
As an aid in the control of outbreaks of necrotic enteritis in chickens caused by
Clostridium perfringens.
For the prevention and control of enzootic pneumonia, and scours caused by
organisms (e.g. Lawsonia intracellularis) sensitive to tylosin, in pigs.
For the control of pneumonia in cattle associated with mycoplasmata and
Pasteurella multocida
For information regarding swine dysentery see section 3.5.

In calves, the veterinary medicinal product can also be administered through milk
or milk replacer.
1.1 gram of the veterinary medicinal product corresponds to 1 gram of tylosin.
The dosages are as follows:
Chickens and turkeys:
For the control of chronic respiratory disease: 50 – 200 mg tylosin per kg BW per
day (corresponding to 55 – 220 mg of the veterinary medicinal product per kg
BW) for 5 days.
As an aid in the control of outbreaks of necrotic enteritis caused by Clostridium
perfringens in chickens: 20-50 mg tylosin per kg BW per day (corresponding to
22-55 mg of the veterinary medicinal product per kg BW) for 5 days, depending
on the age and the water consumption of the birds.
Pigs:
For the treatment of enzootic pneumonia: 25 mg tylosin/kg BW (corresponding to
27.5 mg of the veterinary medicinal product per kg BW). A medicated solution of
drinking water should generally be administered until 24 hours after scouring or
respiratory symptoms have ceased, normally 3-10 days. The diagnosis should be
reviewed if there is no response after 5 days of medication.
For the treatment of ileitis:
5 – 10 mg tylosin per kg BW per day (corresponding to 5.5 – 11 mg of the
veterinary medicinal product per kg BW) for 3 – 10 days.
Calves:
1.1 g of the veterinary medicinal product should be incorporated in milk or milk
replacer twice daily for each calf. This should be continued for 7-14 days
dependent on response.
The intake of medicated water/ milk/ milk replacer depends on the clinical
condition of the animals. In order to obtain the correct dosage, the concentration
of tylosin may need to be adjusted accordingly.
To ensure a correct dosage, body weight should be determined as accurately as
possible.
Based on the recommended dose and the number and weight of animals to be
treated, the exact daily concentration of the veterinary medicinal product should
be calculated according to the following formula:
…… mg veterinary medicinal product per average body weight (kg)
kg body weight per day x of animals to be treated

average daily water or milk intake (l/animal)
= …...mg veterinary medicinal
product per litre of drinking water or
milk

Do not use in cases of hypersensitivity to the active substance or other
macrolides.

None known.
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a
veterinarian, to either the marketing authorisation holder or the national
competent authority via the national reporting system. See the package leaflet for
respective contact details.

None.

Special precautions for safe use in the target species:
Use of the product should be based on identification and susceptibility testing of
the target pathogen(s). If this is not possible, therapy should be based on
epidemiological information and knowledge of susceptibility of the target
pathogens at farm level, or at local/regional level.
Use of the product should be in accordance with official, national and regional
antimicrobial policies.
A high rate of in vitro resistance has been demonstrated in European strains of
Brachyspira hyodysenteriae implying that the product will not be sufficiently
efficacious against swine dysentery.
Use of the product deviating from the instructions given in the SPC may increase
the prevalence of bacteria resistant to tylosin and may decrease the
effectiveness of treatment with other macrolides, lincosamides and streptogramin
B due to the potential for cross-resistance.
Special precautions to be taken by the person administering the veterinary
medicinal product to animals
Tylosin may induce irritation. Macrolides, such as tylosin, may also cause
hypersensitivity (allergy) following injection, inhalation, ingestion or contact with
skin or eye. Hypersensitivity to tylosin may lead to cross reactions to other
macrolides and vice versa. Allergic reactions to these substances may
occasionally be serious and therefore direct contact should be avoided.
To avoid exposure during preparation of the medicated drinking water, wear
overalls, safety glasses, impervious gloves and wear either a disposable half
mask respirator conforming to European Standard EN149 or a non-disposable
respirator to European Standard EN140 with a filter to EN143. Wash hands after
use.
In the event of accidental skin contact, wash thoroughly with soap and water. In
case of accidental eye contact, flush the eyes with plenty of clean, running water.
Do not handle the product if you are allergic to ingredients in the product.
If you develop symptoms following exposure, such as skin rash, you should seek
medical advice and show the physician this warning. Swelling of the face, lips
and eyes or difficulty in breathing are more serious symptoms and require urgent
medical attention.
Special precautions for the protection of the environment:
Not applicable.
Other precautions:
Not applicable.

interaction
None known.

Store in the original container.
Keep the container tightly closed.
Do not store above 25°C. Store in a dry place.

Animals must not be slaughtered for human consumption during treatment.
Chickens, when the veterinary medicinal product is used for the control of
chronic respiratory disease:
Meat and offal: 1 day
Eggs: Zero days
Chickens, when the veterinary medicinal product is used as an aid in the control
of outbreaks of necrotic enteritis caused by Clostridium perfringens (Meat, offal
and eggs): Zero days
Turkeys (meat and offal): Zero days
Pigs (meat and offal): Zero days
Calves (meat and offal): 14 days

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.