Suvaxyn PRRS MLV Lyophilisate and Solvent for Suspension for Injection for Pigs
Active ingredient: Porcine respiratory and reproductive syndrome virus
Form
Injection
Species
Manufacturer
Zoetis Belgium
VMD MA No.
EU/2/17/215/001–003
What it's used for
Specific claims For finishing pigs, the effect of the virus on the respiratory system is most relevant. A significant improvement of rearing results (reduc...
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Suvaxyn PRRS MLV Lyophilisate and Solvent for Suspension for Injection for Pigs — SPC Details
Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.
For finishing pigs, the effect of the virus on the respiratory system is most relevant. A
significant improvement of rearing results (reduced morbidity due to PRRS infection,
and a better daily growth and feed conversion) until the end of the fattening period was
observed in vaccinated pigs during field trials, particularly in piglets vaccinated at 6
weeks of age.
For breeding pigs, the effect of the virus on the reproductive system is most relevant. A
significant improvement of the reproductive performance in PRRS virus contaminated
environments and a reduction of transplacental virus transmission after challenge was
observed in vaccinated pigs.
Onset of immunity: 28 days post vaccination.
Duration of immunity: 24 weeks post
vaccination.
doses per
vial
Volume (ml) of solvent needed forintramuscular
injection
intradermal
application
25
100
50
200
5
20
Before reconstitution, allow the solvent to reach room temperature (15 C – 25 C) and
shake well before use.
Visual appearance after reconstitution: white suspension.
Dosage:
Intramuscular injection: 2 ml in the neck.
Intradermal application: 0.2 ml on top or to the left or right side of the neck, or along the
muscles of the back, using a multi-dose needle-free injection device for intradermal
application of liquids suitable to deliver a “jet-stream” volume of vaccine (0.2 ml ± 10 %)
through the epidermal layers of the skin.
A small, transient, intradermal lump observed after the intradermal application is
indicative of the appropriate vaccination technique.
Vaccination scheme:
A single dose is given to pigs from 2 weeks of age onwards.
Finishing pigs: a single vaccination is sufficient for protection until slaughter.
Breeding pigs: For gilts a (re)vaccination 2-4 weeks before mating is recommended.
To maintain a high and homologous level of immunity, revaccination at regular
intervals is recommended, either before each next gestation or at random at 4 month
intervals. Pregnant sows should only be vaccinated after previous exposure to
European PRRS virus.
Use sterile syringes and needles or clean intradermal equipment.
established through reliable diagnostic methods.
Very common
(>1 animal / 10 animals treated):
Injection site lump
(1)
Rare
(1 to 10 animals / 10,000 animals treated):
Hyperthermia
(2)
, hypersensitivity reactions
(including dyspnoea, hyperaemia,
decubitus, muscle tremor, excitation,
vomiting)
(3)
Very rare
(<1 animal / 10,000 animals treated,
including isolated reports):
Anaphylactic-type reactions
(4)
(1)
After intradermal vaccination a small firm injection site lump (maximum 1.5 cm in
diameter) is observed in fattening pigs and is indicative of the appropriate vaccination
technique. In breeding pigs a mean diameter of approximately 2 cm is observed and in
individual breeding pigs up to 10 cm. These lumps may be accompanied by other signs
of inflammation (pain, reddening, warmth and crusts). This lump is generally seen for
less than 14 days but may occasionally persist for 29 days or longer.
(2)
After intramuscular vaccination.
(3)
These signs disappear spontaneously and totally within a few minutes after vaccination.
(4)
Fatal outcome of anaphylactic-type reactions has been reported very rarely.
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder or its local representative or the national
competent authority via the national reporting system. See also the last section of the
package leaflet for respective contact details.
boars. Do not use in herds where a PRRS eradication programme based on serology
has been adopted.
Maternally derived antibodies may interfere with the response to vaccination.
Vaccinate healthy animals only.
Special precautions for safe use in the target species:
Care should be taken to avoid the introduction of the vaccine strain into an area where
PRRS virus is not already present. The vaccine virus may spread to pigs in contact
during 5 weeks after vaccination. The most common spreading route is via direct
contact, but spreading via contaminated objects or via the air cannot be excluded. Care
should be taken to avoid spread of vaccine virus from vaccinated animals to
unvaccinated animals (e.g.: naïve pregnant sows) that should remain free from PRRS
virus. Do not use in boars producing semen for seronegative herds, as PRRS virus may
be excreted in semen for many weeks.
Do not routinely rotate two or more commercial PRRS MLV vaccines based on
different strains in a herd.
In order to limit the potential risk of recombination between PRRS MLV vaccine strains
of the same genotype, do not use different PRRS MLV vaccines based on different
strains of the same genotype on the same farm at the same time. In the case of
transitioning from one PRRS MLV vaccine to another PRRS MLV vaccine, a transition
period should be respected between the last administration of the current vaccine and
the first administration of the new vaccine. This transition period should be longer than
the shedding period of 5 weeks following vaccination.
PRRS virus-naïve breeding animals (e.g. replacement gilts from PRRS virus-negative
herds) which are introduced into a PRRSV-infected herd should be vaccinated prior to
first insemination. Vaccination should preferably be done in a separated quarantine unit.
A transition period should be respected between vaccination and moving the animals to
the breeding unit. This transition period should be longer than the shedding phase of 5
weeks following vaccination.
Vaccination should aim to achieve a homogenous immunity in the target population at
farm level.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals:
In case of accidental self-injection, seek medical advice immediately and show the
package leaflet or the label to the physician.
Special precautions for the protection of the environment:
Not applicable.
from 3 weeks of age onwards, which demonstrate that this vaccine can be given with
Porcilis PCV M Hyo, with Porcilis Lawsonia, or with a mixture of Porcilis PCV M Hyo
and Porcilis Lawsonia, at the same time, but at separate sites (preferably at the
opposite side of the neck).
In individual pigs the temperature increase after associated use may commonly exceed
2°C. The temperature returns to normal from 1 to 2 days after the peak temperature is
observed. Transient local injection site reactions, which are restricted to a slight injection
site lump (maximum 2 cm diameter),may commonly occur from 5 days after vaccination
onwards, after intradermal and after intramuscular vaccination. These lumps may
occasionally persist until 29 days after vaccination or longer.
Hypersensitivity reactions after vaccination may occur uncommonly.
Safety and efficacy data are available in pigs from 3 weeks of age onwards which
demonstrate that this vaccine can be administered intradermally non-mixed with
Porcilis PCV ID alone or with Porcilis PCV ID mixed with Porcilis Lawsonia ID and/or
non-mixed with Porcilis M Hyo ID ONCE providing that administration site of non-mixed
vaccines is separated by at least 3 cm. Adverse events are as described in section 3.6,
except for injection site lumps of up to 2.5 cm can be observed in individual pigs. These
lumps may last 5 weeks and are very commonly accompanied by redness and crusts.
Hyperthermia on the day of vaccination (mean 0.3 °C, individual pigs up to 1.2 °C) is
common. Lying down and malaise can be uncommonly observed in vaccinated pigs.
The product literature of respective products should be consulted before administration
in association with Porcilis PRRS. No information is available on the safety and
efficacy of the administration of Porcilis PRRS in association with the above-
mentioned products in breeding animals or during pregnancy.
Safety and efficacy data are available in pigs from 3 weeks of age onwards which
demonstrate that this vaccine can be administered intradermally non-mixed with Porcilis
PCV M Hyo ID alone or with Porcilis PCV M Hyo ID mixed with Porcilis Lawsonia ID.
The administration site of non-mixed vaccines should be separated by approximately 3
cm. Adverse events are as described in section 3.6, except for injection site swellings
with a maximum size of up to 15 cm in individual breeding pigs.
Injection site swellings may show other signs of inflammation (pain, reddening, warmth
and crusts). Elevated temperatures (mean 1.1°C, individual breeding pigs up to 2.4°C)
may commonly occur on the day of vaccination. The product literature of Porcilis PCV
M Hyo ID and/or Porcilis Lawsonia ID should be consulted before administration.
No information is available on the safety and efficacy of this vaccine when used with
any other veterinary medicinal product, except the products mentioned above. A
decision to use this vaccine before or after any other veterinary medicinal product
therefore needs to be made on a case by case basis.
Protect from light.
Solvent: store below 25 °C.
This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.
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