Spotinor 10 mg/ml Spot-on Solution for Cattle and Sheep

To avoid resistance, the product should only be used if the susceptibility of the local
fly population to the active substance is assured.
Cases of resistance to deltamethrin have been reported in stinging and nuisance
flies in cattle and lice in sheep.
The product will reduce the number of flies resting directly on the animal but it is not
expected to eliminate all flies on a farm. The strategic use of the product should,
therefore, be based on local and regional epidemiological information about
susceptibility of parasites, and used in association with other pest management
methods.
Care should be taken to avoid the following practices because they increase the risk
of development of resistance and could ultimately result in ineffective therapy:
- too frequent and repeated use of ectoparasiticides from the same class over an
extended period of time;
- underdosing which may be due to underestimation of bodyweight,
misadministration of the product, or lack of calibration of the dosing device.
If clinical signs do not resolve following treatment, the diagnosis should be revised.

Special precautions for safe use in the target species:
The product is for external use only.
Do not apply on or near the animal’s eyes and mucous membranes.
Care should be taken to prevent licking of the product. Avoid use of the product
during extremely hot weather and ensure animals have adequate access to water.
The product should only be administered onto undamaged skin as toxicity is possible
due to absorption from major skin lesions. However, signs of local irritation may
occur after treatment as skin may be already affected by infestation.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals
People with hypersensitivity to deltamethrin or medium-chain triglycerides should
avoid contact with the veterinary medicinal product.
Personal protective equipment consisting of waterproof apron, boots and impervious
gloves should be worn when handling the veterinary medicinal product.
Remove heavily contaminated clothing immediately and wash before use.
Wash splashes from skin immediately with soap and plenty of water.
Wash hands and exposed skin after handling this product and before meals.
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In case of contact with eyes, rinse immediately with plenty of clean, running water
and seek medical advice and show the package leaflet or the label to the physician.
In case of accidental ingestion, wash out mouth immediately with plenty of water and
seek medical advice immediately and show the package leaflet or the label to the
physician.
Do not smoke, drink or eat while handling the product.
This product contains deltamethrin which may produce tingling, itchiness and blotchy
redness on exposed skin. If you feel unwell after working with this product, consult
your doctor and show this label.
To the physician:
Advice on clinical management is available from the National Poisons Information
Service.
Special precautions for the protection of the environment:
Deltamethrin is very toxic to dung fauna, aquatic organisms and honey bees, is
persistent in soils and may accumulate in sediments.
The risk to aquatic ecosystems and dung fauna can be reduced by avoiding too
frequent and repeated use of deltamethrin (and other synthetic pyrethroids) in cattle
and sheep, e.g. by using a single treatment per year on the same pasture.
The risk to aquatic ecosystems will be further reduced by keeping treated cattle
away from water bodies for four weeks after treatment.
Other precautions:
Extra-label use of the product in the non-target species dogs and cats can lead to
toxic neurological signs (ataxia, convulsions, tremors), digestive signs
(hypersalivation, vomiting) and may be fatal.