Rhemox 500 mg/g Powder for Use in Drinking Water for Pigs, Chicken Broilers, Duck Broilers and Turkeys for Meat Production

In drinking water use and in-feed use in pigs.
In drinking water use in chickens.
Appearance of the product after dissolution in water: Colourless to pale yellowish
solution.
Chickens:
The recommended dosage is 16 mg amoxicillin trihydrate per kg body weight per day
(corresponding to 14 mg amoxicillin/kg body weight, or 20 mg of the veterinary
medicinal product/kg body weight) administered in the drinking water, for 3-5 days.
Pigs:
The recommended dosage is 16 mg amoxicillin trihydrate per kg body weight per day
(corresponding to 14 mg amoxicillin/kg body weight, or 20 mg of the veterinary
medicinal product/kg body weight), for 3-5 days.
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In-water use:
For the preparation of medicated water the body weight of the animals to be treated
and their actual daily water consumption should be taken into account. The intake of
medicated water depends on the clinical condition of the animals and other factors,
like breed and husbandry system (e.g. different temperature, different light regimes).
In order to obtain the correct dosage, the concentration of amoxicillin may need to be
adjusted accordingly.
To ensure a correct dosage, body weight should be determined as accurately as
possible.
The use of suitably calibrated measuring equipment is recommended.
Based on the recommended dose and the number and weight of animals to be
treated, the exact daily concentration of the veterinary medicinal product should be
calculated according to the following formula:
x mg veterinary medicinal
product per kg bodyweight
per day
X
mean body weight
(kg) of animals to be
treated
mean daily water consumption (L)
per animal
=
x mg veterinary
medicinal product per
litre drinking water
Bolus dosage: It is recommended to administer the veterinary medicinal product once
daily via the drinking water for a limited period of time. Restrict access to the drinking
water system for approx. two hours (shorter time in warm weather) until the time of
medication. Scatter the calculated daily quantity of powder on the surface of 5-10
litres water. Mix thoroughly until the powder has dissolved. Mix this solution by
stirring into the volume of drinking water that will be consumed within about 2 hours.
Maximum solubility of the veterinary medicinal product in water is approximately 8 g/L
at room temperature (approximately 20 °C). The maximum solubility can be
considerably reduced at lower temperatures. The complete dissolution of the powder
should be ensured.
Continuous treatment: Preparation of medicated water should provide an amount to
be consumed within the next 12 hours. Any unused medicated water should be
discarded after 12 hours, and freshly medicated water for the next 12 hours should
be prepared. The maximum concentration of the pre-diluted medicated water is
approximately 8 g/L at room temperature (approximately 20 °C). The maximum
solubility can be considerably reduced at lower temperatures. The complete
dissolution of the powder should be ensured. The proportioner setting should be
changed accordingly. In target animal species, water uptake may vary due to various
factors, including environmental temperature, age and type of feed.
Make sure the animals do not have access to non-medicated water during the period
when the medicated water is given. When all medicated water has been consumed,
turn on the normal water supply again. After the end of the medication period the
water supply system should be cleaned appropriately to avoid intake of sub-
therapeutic amounts of the active substance.
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In-feed use in pigs:
The veterinary medicinal product may also be offered via the feed at the
recommended daily dose. This way of administration is only intended for the
treatment of individual pigs on farms where only a small number of pigs are to
receive the treatment. Only the pack size of 100 g is suitable for the in-feed use.
Larger groups should be treated with medicated drinking water.
Before each administration the powder should be thoroughly mixed into a small
amount of food and should be given directly to the animal before the main ration.
Care should be taken to ensure complete consumption of all medicated feed prior to
providing the remainder of the daily feed ration.
When used in feed for the treatment of individual pigs, the veterinary medicinal
product should be mixed with a sufficient quantity of feed to ensure consumption of
the entire dose prior to providing the remainder of the daily feed ration.