Amoxicillin Global Vet Health 500 mg/g, Powder for Use in Drinking Water for Chickens, Turkeys, Ducks and Pigs

Prepare the solution with fresh potable water immediately before use.
AN: 02189/2024 & 02192/2024
Any medicated water which is not consumed within 24 hours should be discarded
and the medicated drinking water replenished.
In order to ensure consumption of the medicated water, animals should not have
access to other water supplies whilst being treated.
Use the following formula in order to calculate the concentration of the product (mg)
per litre of drinking water:
mg veterinary medicinal
product / kg body weight
per day
x
average body weight
(kg) of animals to be
treated
average daily water intake (l/animal)
= mg veterinary
medicinal product per
litre of drinking water

To ensure a correct dosage, bodyweight should be determined as accurately as
possible to avoid underdosing. The uptake of medicated water depends on the
clinical condition of the animal. In order to obtain the correct dosage the
concentration of amoxicillin has to be adjusted taking into account water intake.
The maximum solubility of the product was only demonstrated at 5 g/L at 20º C.
Below 20º C and above 5 g/L, the product cannot be satisfactorily dissolved. For
stock solutions and when using a proportioner, take care not to exceed the maximum
solubility which can be achieved under the given conditions. Adjust the flow rate
settings of the dosing pump according to concentration of the stock solution and
water intake of the animals to be treated.
After the end of the medication period, the water supply system should be cleaned
appropriately to avoid intake of sub-therapeutic amounts of the active substance.
Chickens:
The recommended dosage is 15 mg amoxicillin trihydrate per kg bodyweight per day
(corresponding to 30 mg product/kg bodyweight/day).
The total period of treatment should be for 3 days or in severe cases for 5 days.
Ducks:
The recommended dosage is 20 mg amoxicillin trihydrate per kg bodyweight per day
(corresponding to 40 mg product/kg bodyweight/day) for 3 consecutive days.
Turkeys:
The recommended dosage is 15-20 mg amoxicillin trihydrate per kg bodyweight per
day (corresponding to 30 - 40 mg product/kg bodyweight/day) for 3 days or in severe
cases for 5 days.
Pigs:
For the medication of pigs, the product may be administered via drinking water or
administered by addition to liquid feeds produced with commercial feed. It may not be
used in dry feeds.
Administration in drinking water:
Administer in the drinking water to give 20 mg amoxicillin trihydrate per kg
bodyweight (corresponding to 40 mg product/kg bodyweight/day) daily for up to 5
days.
AN: 02189/2024 & 02192/2024
Prepare the solution by carefully mixing the product in the requisite quantity of fresh
potable water immediately before use. The dose should be administered at
approximately 24 hourly intervals for up to 5 days.
Any medicated water which is not consumed within 24 hours should be discarded
and the medicated drinking water replenished.
In order to ensure consumption of the medicated water, animals should not have
access to other water supplies whilst being on treatment
Administration in liquid feed:
Administer in liquid feed to give 20 mg amoxicillin trihydrate per kg bodyweight
(corresponding to 40 mg product/kg bodyweight/day) daily for up to 5 days.
Medicated feed should be freshly prepared on at least 3 occasions per day over the
treatment period. The daily dose should be calculated based on the number of
animals and average weight and then divided by the number of feed lots prepared in
the day.
Medicated liquid feed should be prepared with fresh potable water.
After adding the product to some or all of the water needed to make the liquid feed,
ensure the product is fully dissolved. Dissolution of the product can take up to 10
minutes. This medicated water can then be mixed with the dry complete meal and if
appropriate, the remaining water. The system used should ensure that the medicated
water is evenly distributed into the feed. Once prepared the final medicated liquid
feed should be fed to the pigs immediately.
The medicated liquid feed should not be fermented and should not be stored.
Stability of amoxicillin in all commercial feeds has not been established. In order to
ensure that any loss of amoxicillin activity is minimized, the quantity of medicated
liquid feed prepared should not exceed the amount of feed which will be consumed
within 4 hours.
Any medicated liquid feed which is not consumed within 4 hours should be discarded
Although restricted access to other water supplies would help ensure medicated
liquid feed is consumed, separate clean potable water should remain available at all
times for welfare reasons.
The veterinary medicinal product is to be administered only for the treatment of
individually fed animals or a small group of animals where the intake by individual
animals can be effectively controlled.