POM-V Prescription Required

Reprocine 0.07 mg/ml Solution for Injection for Cattle and Pigs

Active ingredient: Carbetocin

Form

Injection

Species

Cattle Pigs

Manufacturer

Vetoquinol UK Limited

VMD MA No.

08007/5014

What it's used for

Cow: - Uterine atony during the puerperal period, - Placental retention as a consequence of uterine atony - Initiation of milk ejection in stress-induced a...

Full indications, dosage and side effects ↓

View official SPC (PDF)

The prescription itself has a price. See what practices near you charge for a consultation and the written prescription fee.

Paying less for Carbetocin

1

Ask your vet for a written prescription

They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.
2

Fill it at a registered online retailer

The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

Your prescription rights → VMD register of retailers →

Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Reprocine 0.07 mg/ml Solution for Injection for Cattle and Pigs — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 26 Mar 2026.

Cow:
- Uterine atony during the puerperal period,
- Placental retention as a consequence of uterine atony
- Initiation of milk ejection in stress-induced agalactia or in conditions requiring udder
emptying
Sow:
- Uterine atony during the puerperal period
- Supportive therapy of mastitis-metritis-agalactia (MMA-) syndrome
- Initiation of milk ejection
- Shortening of total parturition duration in sows: either after delivery of the first piglet or as a
component of synchronisation of parturition in sows, which have not farrowed 24 hours
after administration of an appropriate PGF2

(e.g. cloprostenol) not before day 113 of
pregnancy.

Revised: July 2025
MA split from NI following AN: 01085/2025Page 2 of 5

Cows
For all indications: 3.0 – 5.0 ml/animal, corresponding to 0.21 – 0.35 mg carbetocin/animal
Sows
For uterine atony, MMA and milk ejection:
1.5 – 3.0 ml/animal, corresponding to 0.105 – 0.21 mg carbetocin/animal
For shortening of total parturition duration as a part of the synchronisation of parturition:
1.0 ml/animal, corresponding to 0.07 mg carbetocin/animal
The dosage requirements can be variable within the indicated limits based on the

Revised: July 2025
MA split from NI following AN: 01085/2025Page 3 of 5
assessment of the veterinarian.
For single intramuscular or intravenous injection.
In case of treatment for milk ejection in the cow and sow or supportive therapy in
MMA-syndrome in sow, a repeated administration is possible after 1 to 2 days.
Special information:
The responsiveness to carbetocin of the myometrium is likely to be close to zero from the 5
th

to the 11
th
day post partum. Therefore, the administration of the veterinary medicinal product
during this period is likely to be inefficient and should be avoided.
If treatment with carbetocin should fail, then it is advisable to reconsider the aetiology of the
condition, specifically if hypocalcaemia could be a complicating factor.
In case of severe septic metritis, appropriate concomitant therapy should be instigated when
administering the veterinary medicinal product.

Do not administer to accelerate parturition if cervix is not opened or if there is a mechanical
cause for the delayed parturition such as physical obstruction, positional and postural
abnormalities, convulsive labour, threatened rupture of uterus, uterine torsion, relative foetal
oversize or deformities of the birth canal.

None known.

None.

Special precautions for use in animals
The interval between two injections should not be shorter than 24 hours.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals
In case of an accidental self-injection of the veterinary medicinal product in non-pregnant
women the following effects may occur: facial flushing and warmth, lower abdominal pain.
These effects usually disappear within a short span of time.
Pregnant women, women post partum and breast-feeding women should not use this
product, in order to avoid an accidental exposure.
contractions could be induced in pregnant women.

The administration of oxytocin after the administration of the veterinary medicinal product is
unnecessary. Due to a possible intensification of the effect of oxytocin, undesirable uterine
spasms may be induced.

Store in a refrigerator (2 - 8 °C). Keep container in the outer carton.
When transported in a vehicle by a veterinarian, the veterinary medicinal product should be
kept in a cooler box.

Sows
For uterine atony, MMA and milk ejection:
1.5 – 3.0 ml/animal, corresponding to 0.105 – 0.21 mg carbetocin/animal
For shortening of total parturition duration as a part of the synchronisation of parturition:
1.0 ml/animal, corresponding to 0.07 mg carbetocin/animal
The dosage requirements can be variable within the indicated limits based on the

Revised: July 2025
MA split from NI following AN: 01085/2025Page 3 of 5
assessment of the veterinarian.
For single intramuscular or intravenous injection.
In case of treatment for milk ejection in the cow and sow or supportive therapy in
MMA-syndrome in sow, a repeated administration is possible after 1 to 2 days.
Special information:
The responsiveness to carbetocin of the myometrium is likely to be close to zero from the 5
th

to the 11
th
day post partum. Therefore, the administration of the veterinary medicinal product
during this period is likely to be inefficient and should be avoided.
If treatment with carbetocin should fail, then it is advisable to reconsider the aetiology of the
condition, specifically if hypocalcaemia could be a complicating factor.
In case of severe septic metritis, appropriate concomitant therapy should be instigated when
administering the veterinary medicinal product.
4.10 Overdose (symptoms, emergency procedures, antidotes), if necessary
Injection of more than twice the recommended dose rate (more than 0.4 mg of
carbetocin/animal) could increase the stillbirth rate in older sows if administered during
prolonged parturition.
A threefold overdose (0.6 mg of carbetocin/animal) may induce profuse lactation in sows
that may result in diarrhoea, reduced weight gain and increased mortality in their piglets.
Carbetocin is considered as moderately irritant. At the injection sites of treated animals,
focal lymphocytic infiltration was observed at higher doses (1.0 mg of carbetocin/animal).
4.11 Withdrawal periods
Cattle, pig meat and offal: Zero days
Cattle milk: Zero days
5.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.