POM-V Prescription Required

Regumate Equine 2.2 mg/ml Oral Solution for Horses

Active ingredient: Altrenogest

Form

Liquid

Species

Horses

Manufacturer

Intervet International B.V.

VMD MA No.

06376/3040

What it's used for

• signs of oestrus within 5 days following the end of treatment) and synchronisation of ovulation (60% of mares ovulate between days 11 and 14 following th...

Full indications, dosage and side effects ↓

View official SPC (PDF)

The prescription itself has a price. See what practices near you charge for a consultation and the written prescription fee.

Paying less for Altrenogest

1

Ask your vet for a written prescription

They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.
2

Fill it at a registered online retailer

The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

Your prescription rights → VMD register of retailers →

Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Regumate Equine 2.2 mg/ml Oral Solution for Horses — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

•
signs of oestrus within 5 days following the end of treatment) and
synchronisation of ovulation (60% of mares ovulate between days 11 and
14 following the end of treatment).

Carefully withdraw the volume of veterinary medicinal product corresponding to the
mare bodyweight (1 ml per 50 kg bodyweight) and administer this volume via oral
route.
- 150, 300 and 1000 ml bottles: Wearing gloves remove the original cap and in its
place screw on the luer lock cap. Keeping the bottle upright, screw the syringe onto the
luer lock cap orifice, turn the bottle upside down, and carefully withdraw the solution
from the bottle using the syringe.
Turn the bottle right way up before detaching the syringe. Securely replace the small
cap on the luer lock cap.
- 250 ml bottles: Remove the white cap and the aluminium foil seal from the neck of
the measuring compartment. Keeping the bottle upright, press the body of the bottle
until the required volume of veterinary medicinal product is accumulated into the
measuring compartment. Carefully pour the content of the measuring compartment on
the mare feed.
The veterinary medicinal product should be added to the mare’s feed, at a single
feeding per day, or directly administered into the mouth using a syringe.
Avoid introduction of contamination.

Do not use in mares where uterine infection has been diagnosed.
Do not use in males.

Horses (mares):
Very rare
(<1 animal / 10,000 animals
treated, including isolated
reports):
Uterine infection
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder or the national competent authority via the
national reporting system. See the package leaflet for respective contact details.

In order to ensure effective use of the veterinary medicinal product, the presence of
follicular activity in mares must be confirmed during the transitional period.

Special precautions for safe use in the target species:
The medicated feed should be offered to mares being treated as soon as the veterinary
medicinal product has been added, and not stored. Part consumed feed must be safely
destroyed and not given to any other animal.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals:
Women who may be, or are pregnant, should not use the veterinary medicinal
product. Women of childbearing age should avoid contact with the veterinary
medicinal product.
This veterinary medicinal product should not be handled by persons with known or
suspected progesterone-dependent tumours or thrombo-embolic disorders.
Direct contact with the skin should be avoided. Personal protective clothing (gloves
and overalls) must be worn when handling the veterinary medicinal product. Porous
gloves may let this veterinary medicinal product pass through. Transcutaneous
absorption may be even higher when the area is covered by an occlusive material,
such as latex or rubber gloves. Accidental spillage on the skin should be washed off
immediately with soap and water.
Wash hands after treatment and before meals.
In case of incidental contact with eye, rinse thoroughly with water for 15 minutes. Get
medical attention.
Effects of overexposure: repeated accidental absorption could lead to disruption of
the menstrual cycle, uterine or abdominal cramping, increased or decreased uterine
bleeding, prolongation of pregnancy or headache.
Special precautions for the protection of the environment:
Not applicable.

Griseofulvin may alter the effects of altrenogest if administered concomitantly with
this veterinary medicinal product.

This veterinary medicinal product does not require any special storage conditions.

Meat and offal: 9 days.
Not authorised for use in lactating animals producing milk for human consumption.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.