POM-V Prescription Required

Porcilis ColiClos

Active ingredients: Clostridium perfringens, Escherichia coli

Form

Injection

Species

Pigs

Manufacturer

MSD Animal Health UK Limited

VMD MA No.

01708/5053

What it's used for

strains, which express the adhesins F4ab (K88ab), F4ac (K88ac), F5 (K99) or F6 (987P) and caused by C. perfringens type C.

Full indications, dosage and side effects ↓

View official SPC (PDF)

The prescription itself has a price. See what practices near you charge for a consultation and the written prescription fee.

Paying less for Clostridium perfringens + Es...

1

Ask your vet for a written prescription

They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.
2

Fill it at a registered online retailer

The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

Your prescription rights → VMD register of retailers →

Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Porcilis ColiClos — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

strains, which express the adhesins F4ab (K88ab), F4ac (K88ac), F5 (K99) or F6
(987P) and caused by C. perfringens type C.

Administer 1 dose (2 ml) of vaccine per animal in the neck in the area behind the ear.
Before use, allow the vaccine to reach room temperature.
Shake vigorously before use and at intervals during use.
Vaccination scheme:
Primary vaccination: Sows/gilts which have not yet been vaccinated with the product
are given a primary injection 6 to 8 weeks before the expected date of farrowing and
a second injection 4 weeks later.
Revaccination: A single revaccination is carried out 2 to 4 weeks before the expected
date of farrowing.

None.

Pigs (sows and gilts):
Very common
(>1 animal / 10 animals treated):
Elevated temperature
, Injection site
swelling
.
Common
(1 to 10 animals / 100 animals):
Decreased activity
, Appetite loss
.Very rare
(<1 animal / 10 000 animals
treated, including isolated reports):
Hypersensitivity reaction.
Up to 2 °C on the day of vaccination.
Sometimes painful and hard up to 10 cm in diameter for up to 25 days.
On the day of vaccination.
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder or the national competent authority via the
national reporting system. See the package leaflet for respective contact details.

Vaccinate healthy animals only.

Special precautions for safe use in the target species:
Protection of piglets is achieved by colostrum intake. Therefore, care should be taken
to ensure that each piglet ingests a sufficient quantity of colostrum.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals
In case of accidental self-injection, seek medical advice immediately and show the
package leaflet or the label to the physician.

No information is available on the safety and efficacy of this vaccine when used with
any other veterinary medicinal product. A decision to use this vaccine before or after
any other veterinary medicinal product therefore needs to be made on a case-by-
case basis.

Store in a refrigerator (2 °C – 8 °C).
Do not freeze.
Protect from light.

Zero days.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.