POM-V Prescription Required

Oestracton 52.4 Micrograms/ml Solution for Injection for Cattle, Horses, Pigs

Active ingredient: Gonadorelin[6-D-Phe]acetate

Form

Injection

Species

Cattle Horses Pigs

Manufacturer

Vetoquinol UK Limited

VMD MA No.

08007/5047

What it's used for

Control and stimulation of reproduction and improvement of conception rates in cattle and pigs. Treatment of ovarian-related fertility disorders or dysfunc...

Full indications, dosage and side effects ↓

View official SPC (PDF)

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Clinical information

Oestracton 52.4 Micrograms/ml Solution for Injection for Cattle, Horses, Pigs — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 26 Mar 2026.

Control and stimulation of reproduction and improvement of conception rates in cattle
and pigs. Treatment of ovarian-related fertility disorders or dysfunctions in cattle and
horses.
Cattle:
- Ovulation induction in case of delayed ovulation due to LH-deficiency
- Ovulation synchronization following oestrus synchronisation
- Stimulation of the ovaries during the puerperal period from Day 12 post partum
- Ovarian cysts (due to LH-deficiency).
Horses:
- Acyclia and anoestrus due to LH-deficiency
- Ovulation induction (shortening of oestrus).
Pigs:
- Ovulation synchronization in association with a PMSG for timed insemination as part
of a timed insemination-regime

Revised: December 2025
MA split from NI MA following AN: 02299/2025Page 2 of 6

For single intramuscular or subcutaneous injection.
The cap may be safely punctured up to 20 times. When treating groups of animals in
one run, it is recommended to use a draw-off needle that has been placed in the vial
stopper to avoid excess broaching of the stopper. The draw-off needle should be
removed after treatment.
Cows and heifers: 1.0 – 2.0 ml intramuscular
(corresponding to 50 – 100 µg of Gonadorelin[6-D-Phe] per animal)
- Ovulation induction in case of delayed ovulation due to LH-deficiency 2.0 ml
- Ovulation synchronisation following oestrus synchronisation 1.0 ml
- Stimulation of the ovaries in the puerperal period from Day 12 post partum 1.0 ml
- Ovarian cysts (due to LH-deficiency) 1.0 ml
Mares: 2.0 ml intramuscular
(corresponding to 100 µg of Gonadorelin [6-D-Phe] per animal)
Sows and gilts: 0.5 – 1.5 ml intramuscular or subcutaneous
(corresponding to 25 – 75 µg of Gonadorelin[6-D-Phe] per animal)
- Ovulation synchronization in association with a PMSG for timed insemination as part
of a timed insemination-regime
- adult sows 0.5 – 1.0 ml
- gilts 1.0 – 1.5 ml
Special information
The ovulation synchronization system includes the administration of PMSG and
Oestracton after the end of oestrus synchronisation (OeS) (e. g. with Altrenogest) in
gilts or after the weaning in adult sows and two artificial inseminations (AI) within a
period of 40 – 42 hours.
In adult sows the time table depends on the duration of the suckling period.
Adult sows (suckling period ≥
Interval between weaning and PMSG administration: 24 hours
Interval between PMSG and Oestracton administration: 56 hours (± 1 hour)
Interval between Oestracton and AI1: 24 – 26 hours
Interval between Oestracton and AI2: 40 – 42 hours
The preferred dose of Oestracton is 50 µg. However, the administration of 25 µg is
also sufficient in case of sows with sow parity of more than 3 or during the mating
period of September until May.

Revised: December 2025
MA split from NI MA following AN: 02299/2025Page 4 of 6
In case of shorter suckling periods the time interval between PMSG and Oestracton
should be extended accordingly:
Suckling period of 4 weeks: 72 hours
Suckling period of 3 weeks: 78 – 80 hours
The time between the Oestracton administration and the both AI’s remain unchanged.
Gilts:
Interval between OeS and PMSG administration: 24 hours after termination
of OeS
Interval between PMSG and Oestracton administration: 78 – 82 hours
Interval between Oestracton and AI1: 24- 26 hours
Interval between Oestracton

and AI2: 40 hours
The preferred dose of Oestracton is 50 µg. However, the dose may be adjusted within
the range of 50 – 75 µg to take into account farm-specific aspects or seasonal
influences. The proposed time table should be strictly kept.

- Do not use in cows with a mature tertiary follicle ready to ovulate.
- Do not use during infectious diseases and other relevant health disorders.
- Do not use in case of known hypersensitivity to the active substance or to any of the
excipients.

None known.

To maximise conception rates of cows to be treated with GnRH-PGF 2α based
synchronization protocols, the ovarian status should be determined and regular cyclic
ovarian activity confirmed. Optimal results will be achieved in healthy normally cycling
cows

Special precautions for use in animals
None
Special precautions to be taken by the person administering the veterinary medicinal
product to animals
Care should be taken when handling the product to avoid self-injection. In case of
accidental self- injection, seek medical advice immediately and show the package
leaflet or the label to the physician.
The effects of accidental exposure in pregnant women or in women with normal
reproductive cycles are unknown; therefore it is recommended that pregnant women
should not administer the product, and that women of child-bearing age should
administer the product with caution.
Care should be taken to avoid skin and eye contact. In case of skin contact, rinse
immediately and thoroughly with water as GnRH analogues can be absorbed through
the skin. In case of accidental contact with eyes, rinse thoroughly with plenty of water.
People with known hypersensitivity to GnRH analogues should avoid contact with the
veterinary medicinal product.

A synergistic effect occurs in case of a combined administration of FSH, especially in
case of a disturbed puerperal course. Simultaneous use of human or equine chorionic
gonadotropin may lead to ovarian over-stimulation.

Store in a refrigerator (2 - 8 °C). Keep the vials in the outer carton.

Cattle, horse, pig meat and offal: Zero days
Cattle, horse milk: Zero hours
5.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.