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POM-V Prescription Required Companion Animal

Marbotis 3mg/ml + 10mg/ml + 1mg/ml Ear Drops, Suspension for Dogs

Active ingredients: Clotrimazole, Dexamethasone, Dexamethasone Acetate, Marbofloxacin

Form

Drops

Species

Dogs

Manufacturer

Vet-Agro Multi-Trade Company Sp. z o.o.

VMD MA No.

55788/5000

What it's used for

Treatment of otitis externa of bacterial and fungal origin – respectively due to bacteria sensitive to marbofloxacin, and fungi (Malassezia pachydermatis s...

Full indications, dosage and side effects ↓
View official SPC (PDF)

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  1. 1

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    They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.

  2. 2

    Fill it at a registered online retailer

    The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Marbotis 3mg/ml + 10mg/ml + 1mg/ml Ear Drops, Suspension for Dogs — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 26 Mar 2026.

Treatment of otitis externa of bacterial and fungal origin – respectively due to
bacteria sensitive to marbofloxacin, and fungi (Malassezia pachydermatis
sensitive to clotrimazole).

Issued: September 2024
AN: 03310/2022
Do not administer to dogs suffering from perforation of the tympanic membrane.
Do not use in cases of hypersensitivity to the active substance, or to any of the
excipients.
Do not administer to pregnant or lactating bitches.
Dogs:
Undetermined frequency
(cannot be estimated from the
available data)
Elevated serum alkaline phosphatase (ALP) and
aminotransferase*
Neutrophilia (limited)*
Adrenal gland disorder (suppression of function)**
Skin thinning**
Delayed healing (wounds)**
Rare
(1 to 10 animals / 10,000
animals treated):
Deafness***
* Usual adverse reactions associated with corticosteroid drugs such as
changes in biochemical and haematological parameters may be observed.
** Prolonged and intensive use of topical corticosteroid preparations is known
to trigger local and systemic effects
***Mainly in elderly dogs and mostly of a transient nature
Reporting adverse events is important. It allows continuous safety monitoring of
a veterinary medicinal product. Reports should be sent, preferably via a
veterinarian, to either the marketing authorisation holder <or its local
representative> or the national competent authority via the national reporting
system. See the package leaflet for respective contact details.
None.

Special precautions for use in animals
Use of the product should be based on identification and susceptibility testing of
the target pathogen(s). If this is not possible, therapy should be based on
epidemiological information and knowledge of susceptibility of the target
pathogens at farm level, or at local/regional level. Use of the product should be
in accordance with official, national and regional antimicrobial policies.
An antibiotic with a lower risk of antimicrobial resistance selection (lower AMEG
category) should be used for first line treatment where susceptibility testing
suggests the likely efficacy of this approach.
Before treating with the veterinary medicinal product, the integrity of the
tympanic membrane must be verified.
The external ear canal should be meticulously cleaned and dried before
treatment.
Quinolone class drugs have been associated with cartilage erosions in
weightbearing joints and other forms of arthropathy in immature animals of
various species. The use of the veterinary medicinal product in young animals
is not recommended.
Special precautions to be taken by the person administering the veterinary
medicinal product to animals
People with known hypersensitivity to marbofloxacin, dexamethasone,
clotrimazole should avoid contact with the veterinary medicinal product.
This veterinary medicinal product may cause skin and eye irritation. Avoid
contact with skin and eyes. In case of accidental contact, wash exposed area
thoroughly with water.
Wash hands after use.

Issued: September 2024
AN: 03310/2022
In case of accidental ingestion or if skin and eye symptoms persist seek
medical advice immediately and show the package leaflet or the label to the
physician.
Special precautions for the protection of the environment
Not applicable.
Other precautions
Not applicable.
None known.

Issued: September 2024
AN: 03310/2022
Do not store above 30C.
Not applicable.
5.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.

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