Levamole 75 mg/ml Oral Solution

The product may be given to young, pregnant and lactating animals, but due
regard must always be paid to the animals physical condition and the presence
of inter-current disease. When a dosing gun is used to administer the product,
care should be taken to avoid the occurrence of dosing gun pharyngitis.
Care should be taken to avoid the following practices because they increase the
risk of development of resistance and could ultimately result in ineffective
therapy:
•
over an extended period of time.
•
misadministration of the product, or lack of calibration of the dosing
device (if any).
Suspected clinical cases of resistance to anthelmintics should be further
investigated using appropriate tests (e.g. Faecal Egg Count Reduction Test).
Where the results of the test(s) strongly suggest resistance to a particular
anthelmintic, an anthelmintic belonging to another pharmacological class and
having a different mode of action should be used.
Resistance to levamisole has been reported in , and
Trichostrongylus species in sheep in a number of countries, including the EU.
There are reports of resistance in Haemonchus in sheep in outside the EU.
Resistance to levamisole has been reported in species in cattle in
developed countries such as New Zealand. Therefore the use of this product
should be based on local (regional, farm) epidemiological information about
susceptibility of nematodes and recommendations on how to limit further
selection for resistance to anthelmintics.

Care should be taken to accurately estimate the bodyweight of animals to be
treated before calculating the dose.
i. Special precautions for use in animals
For oral use only
ii. Special precautions to be taken by the person administering the
veterinary medicinal product to animals
Levamisole can cause idiosyncratic reactions as well as serious
blood disorders in a very small number of people. If symptoms such
as dizziness, nausea or vomiting or abdominal discomfort are
experienced when using this product, or sore mouth /throat or fever
occur shortly afterwards, then medical advice should be sought
immediately. Wash hands and exposed skin before meals and after
work. Remove immediately any contaminated clothing. Wash
splashes from eyes and skin immediately. If irritation persists, consult
your doctor. When using do not eat, drink or smoke.