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Levafas Diamond Oral Suspension

Active ingredients: Levamisole Hydrochloride, Oxyclozanide

Form

Liquid

Species

Cattle Sheep

Manufacturer

Norbrook Laboratories Limited

VMD MA No.

02000/4080

What it's used for

For the treatment and control of both gastrointestinal and pulmonary nematode infections, and adult liver fluke infections. Removes most mature Fasciola (f...

Full indications, dosage and side effects ↓
View official SPC (PDF)

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Prescription required

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Clinical information

Levafas Diamond Oral Suspension — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 26 Mar 2026.

For the treatment and control of both gastrointestinal and pulmonary nematode
infections, and adult liver fluke infections. Removes most mature Fasciola
(flukes) present in the bile ducts of the liver
Thoroughly shake the container well before use to ensure that the two active
substances are homogeneously resuspended and therefore the animals
receive the correct dose.
Dosing must be carried out using a suitable gun system, at a rate of 7.5 mg/kg
bodyweight levamisole hydrochloride and 15 mg/kg bodyweight oxyclozanide
achieved by administering 2.5 ml per 10 kg bodyweight in cattle and 0.5 ml per
2 kg bodyweight in sheep.

Revised: April 2023
AN: 03462/2022
To ensure administration of a correct dose, bodyweight should be determined
as accurately as possible; accuracy of the dosing device should be checked.
Animals should be dosed according to their individual weight, and not dosed as
per the heaviest animal in the group, otherwise signs of overdose may occur
(see section 4.10).
Do not mix with other products.
Animals must not be treated within a period of 14 days before or after treatment
with organophosphorus compounds.

Revised: April 2023
AN: 03462/2022
At normal oxyclozanide dose levels, cattle may show slight softening of
the faeces with the occasional animal showing increased frequency of
defecation and transient inappetence. Rarely, animals may also display signs
of ataxia, incoordination, recumbency and depression. Photosensitisation
associated with inflammation of the skin (particularly non pigmented skin e.g.
muzzle, udder) has been observed to occur very rarely and which may be
painful and lead to skin sloughing in severe cases.
Additionally, rarely, sheep may show an allergic reaction such as
submandibular oedema, ear flap oedema and swelling of the head. If such a
reaction occurs, appropriate treatment should be administered without delay.
Such reactions may evolve to a more severe condition (anaphylaxis), which
may be life-threatening.
The frequency of adverse reactions is defined using the following convention:
- rare (more than 1 but less than 10 animals in 10,000 animals treated)
Care should be taken to avoid the following practices because they increase
the risk of development of resistance and could ultimately result in ineffective
therapy:
•
an extended period of time.
•
misadministration of the product, or lack of calibration of the dosing device
(if any)
Suspected clinical cases of resistance to anthelmintics should be further
investigated using appropriate tests (e.g. Faecal Egg Count Reduction Test).
Where the results of the test(s) strongly suggest resistance to a particular
anthelmintic, an anthelmintic belonging to another pharmacological class and
having a different mode of action should be used.
Resistance to levamisole has been reported in Teladorsagia,
Trichostrongylus species in sheep in a number of countries, including the EU.
There are reports of resistance in Haemonchus in sheep outside the EU.
Resistance to levamisole has been reported in Teladorsagia species in cattle in
developed countries such as New Zealand. Therefore the use of this product
should be based on local (regional, farm) epidemiological information about
susceptibility of nematodes and recommendations on how to limit further
selection for resistance to anthelmintics.
Veterinary advice should be sought on appropriate dosing programmes and
stock management to achieve adequate parasite control and reduce the
likelihood of anthelmintic resistance developing.
Do not exceed the recommended dosage.

i. Special precautions for use in animals
Care should be taken to estimate accurately the liveweight of animals to
be treated. Animals should be dosed according to their individual weight,
and not dosed as per the heaviest animal in the group, otherwise signs
of overdose may occur (see section 4.10). It is important that the
container is shaken thoroughly before use to ensure that the two active
substances are homogeneously resuspended and therefore the animals
receive the correct dose.
ii. Special precautions to be taken by the person administering the
veterinary medicinal product to animals
Do not eat, drink or smoke when using this product. Wash splashes
from eyes and skin immediately. If irritation persists seek medical

Revised: April 2023
AN: 03462/2022
advice. Remove any contaminated clothing immediately. Wash hands
and exposed skin after handling this product, and before meals.
Levamisole can cause idiosyncratic reactions and serious blood
disorders in a very small number of people. If symptoms such as
dizziness, nausea, vomiting or abdominal discomfort are experienced
when using this product, or sore mouth/throat or fever occur shortly
afterwards, then medical advice should be sought immediately.
Animals must not be treated within a period of 14 days before or after treatment
with organophosphorus compounds.
Do not store above 25ºC.
Protect from light.
Cattle and sheep may be slaughtered for human consumption only after 5 days
from the last treatment.
This product must not be used in cattle and sheep producing milk for human
consumption.
5.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.

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