Levacide Pour-on Solution 20% w/v

In cases of lungworm infection coughing may persist for some time after
treatment due to tissue damage.
For external use only.
Do not treat animals when wet, and where possible, for one hour post
treatment, prevent treated animals from being exposed to rain.

i) Special precautions for use in animals
Care should be taken to avoid the following practices because they increase
the risk of development of resistance and could ultimately result in ineffective
therapy:
•
an extended period of time.
•
misadministration of the product, or lack of calibration of the dosing
device (if any).
Suspected clinical cases of resistance to anthelmintics should be further
investigated using appropriate tests (e.g. Faecal Egg Count Reduction Test).
Where the results of the test(s) strongly suggest resistance to a particular
anthelmintic, an anthelmintic belonging to another pharmacological class and
having a different mode of action should be used.
Resistance to levamisole has been reported in , and
Trichostrongylus species in sheep in a number of countries, including the EU.
There are reports of resistance in in sheep outside the EU.
Resistance to levamisole has been reported in species in cattle in
developed countries such as New Zealand. Therefore the use of this product
should be based on local (regional, farm) epidemiological information about
susceptibility of nematodes and recommendations on how to limit further
selection for resistance to anthelmintics.
Cattle must not be treated within a period of 14 days before or after treatment
with organophosphorus compounds.
Do not exceed the stated dose.
The bodyweight of animals should be assessed as accurately as possible before
calculating the dose.

Revised: 17
th
December 2008
AN: 00809/2008
As with other anthelmintics, veterinary advice should be sought:
(a) on appropriate dosing programmes and stock management to achieve
adequate parasite control and to reduce the likelihood of anthelmintic
resistance developing;
(b) if the product does not achieve the desired effect, as other diseases,
nutritional disturbances or anthelmintic resistance may be present.
ii) Special precautions to be taken by the person administering the
veterinary medicinal product to animals
Highly flammable. Keep away from heat and sources of ignition.
Do not eat, drink or smoke when using this product. Wear rubber gloves,
boots and waterproof bib-apron when applying this product. Avoid contact
with skin and eyes. In case of accidental skin or eye contact, wash/irrigate
splashes from skin and eyes immediately with clean water. If irritation
persists seek medical advice. Remove any contaminated clothing
immediately. Wash hands and exposed skin after handling this product and
before meals. Use in a well ventilated area.
Levamisole can cause idiosyncratic reactions and serious blood disorders in a
very small number of people. If symptoms such as dizziness, nausea,
vomiting or abdominal discomfort are experienced when using this product or
sore mouth/throat or fever occur shortly afterwards, then medical advice
should be sought immediately.