POM-V Prescription Required

Labiprofen 150 mg/ml Solution for Injection for Cattle, Pigs and Horses

Active ingredient: Ketoprofen

Form

Injection

Species

Cattle Horses Pigs

Manufacturer

Labiana Life Sciences SA

VMD MA No.

32112/3002

What it's used for

- antimicrobial therapy where appropriate. - antimicrobial therapy where appropriate. Pigs: - SyndromePDS- (Metritis Mastitis Agalactia syndrome) in sows,...

Full indications, dosage and side effects ↓

View official SPC (PDF)

The prescription itself has a price. See what practices near you charge for a consultation and the written prescription fee.

Paying less for Ketoprofen

1

Ask your vet for a written prescription

They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.
2

Fill it at a registered online retailer

The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

Your prescription rights → VMD register of retailers →

Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Labiprofen 150 mg/ml Solution for Injection for Cattle, Pigs and Horses — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

-
antimicrobial therapy where appropriate.
-
antimicrobial therapy where appropriate.
Pigs:
-
SyndromePDS- (Metritis Mastitis Agalactia syndrome) in sows, in combination with
antimicrobial therapy, where appropriate.
Horses:
-
musculoskeletal disorders (lameness, laminitis, osteoarthritis, synovitis, tendinitis,
etc.).
-
-

administered via the intravenous or intramuscular route, preferably in the neck region.
The duration of treatment is 1-3 days, and should be established according to the severity
and duration of symptoms.

- Pigs:
3 mg of ketoprofen/kg body weight i.e. 1 ml
administered via the intramuscular route on a single occasion. Depending on the
response observed and based on the benefit-risk analysis by the responsible veterinarian
treatment may be repeated at intervals of 24 hours for a maximum of three treatments.
Each injection should be given at a different site.

- Horses:
2.2 mg of ketoprofen/kg body weight, i.e. 0.75 ml of the product. per 50 kg body weight/
day, administered via the intravenous route.
The duration of treatment is 1-5 days, and should be established according to the severity
and duration of symptoms. In the case of colic one injection is normally sufficient. A
second administration of ketoprofen requires a clinical re-examination.

Do not use in cases of gastro-intestinal ulceration or bleeding, in order not to aggravate
their situation.
Do not use in cases of cardiac, hepatic, or renal disease.
Do not use in cases of known hypersensitivity to ketoprofen or acetyl-salcylic acid or to
any of the excipients.
Do not use in cases of blood dyscrasia, coagulopathy or haemorrhagic diathesis. Do not
administer other non-steroidal anti-inflammatory drugs (NSAIDs) concurrently or within
24 hours of each other.

Undetermined frequency (cannot be
estimated from the available data)
Muscle necrosis
Erosive and ulcerative lesions of the
gastrointestinal tract
Gastric or renal intolerance
Horse
Undetermined frequency (cannot be
estimated from the available data)
Muscle necrosis
Erosive and ulcerative lesions of the
gastrointestinal tract
Gastric or renal intolerance
Injection site reactions
1. After intramuscular injection, subclinical, mild and transient, gradually resolving in the days
after completion of treatment. Administration in the neck region minimizes the extension and
severity of these lesions.
2. After repeated administrations (due to the mechanism of action of ketoprofen).
3. In certain individuals. Due to the action of inhibition of prostaglandins’ synthesis (in common
with all NSAIDS).
4. Transient. Observed after one administration of the product at the recommended volume by
extravascular route. Disappeared after 5 days.
If side effects occur treatment must be stopped, and the advice of a veterinarian should be
sought.
Reporting adverse events is important. It allows continuous safety monitoring of a veterinary
medicinal product. Reports should be sent, preferably via a veterinarian, to either the
marketing authorisation holder or its local representative or the national competent authority
via the national reporting system. See also the section 16 of the package leaflet for
respective contact details.

None.

Do not exceed the recommended dose. Do not exceed the recommended treatment
period.
The use of ketoprofen is not recommended in foals less than one month of age.
When administering to animals of less than 6 weeks of age, ponies or in aged animals it
is necessary to adjust the dose accurately as well as to perform a close clinical follow-up.
Avoid intra-arterial injection.
Avoid use in any dehydrated, hypovolaemic or hypotensive animals as there is a potential
risk of increased renal toxicity.
Since gastric ulceration is a common finding in PMWS (Post-weaning Multisystemic
Wasting Syndrome), the use of ketoprofen in pigs affected by this pathology is not
recommended, in order not to aggravate their situation. In horses, avoid extravascular
administration.

to animals

Hypersensitivity reactions (skin rash, urticaria) could occur. People with known
hypersensitivity to the active substance or to any of the excipients should avoid contact
with the veterinary medicinal product.
Avoid accidental self-injection. In case of accidental self-injection, seek medical advice
immediately and show the package leaflet or the label to the physician.
Avoid contact with the skin, eyes and mucous membranes. In case of accidental skin,
eye or mucous membrane contact, wash the affected area thoroughly with clean running
water immediately. Seek medical advice if irritation persists.
Wash hands after use.
Special precautions for the protection of the environment:
Not applicable.

- Concurrent administration of diuretics or potentially nephrotoxic drugs should be
avoided since there is an increase of renal disturbances, including renal failure. This is
secondary to the diminished blood flow caused by the inhibition of prostaglandins
synthesis.
- Do not administer other non-steroidal anti-inflammatory drugs (NSAIDs),
corticosteroids, anticoagulants or diuretics concurrently or within 24 hours of
administration of the product since the risk of gastrointestinal ulceration and other
adverse reactions may be exacerbated.
- The treatment free period should however take into account the pharmacological
properties of the products used previously.
- Ketoprofen is highly bound to plasma proteins and may compete with other highly bound
drugs which can lead to toxic effects.

Keep the vial in the outer carton in order to protect from light.

Cattle:
Meat and offal: 2 days
Milk: zero hours

Horses:
Meat and offal: 1 day
Milk: Not authorised for use in mares producing milk for human consumption

Pig:
Meat and offal: 3 days

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.