KetoProPig 100 mg/ml Oral Solution for Use in Drinking Water for Pigs
Active ingredient: Ketoprofen
Form
Liquid
Species
Manufacturer
Labiana Life Sciences S.A.U
VMD MA No.
32112/4000
What it's used for
Symptomatic treatment for reduction of pyrexia in cases of acute infectious respiratory disease in fattening pigs in combination with an appropriate anti-...
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KetoProPig 100 mg/ml Oral Solution for Use in Drinking Water for Pigs — SPC Details
Source: VMD Summary of Product Characteristics (SPC). Last updated 26 Mar 2026.
respiratory disease in fattening pigs in combination with an appropriate anti-
infective therapy.
drinking water. Administration over a 24 hour period is recommended.
Medicated water should be the only water supply during the period of
treatment. Medicated water should be refreshed every 24 hours. The
product may be put directly into the header tank or introduced via a water
proportioner pump. Once the treatment period has finished, the pigs should
be given unmedicated water.
Revised: October 2013
AN: 01121/2012
The recommended daily dose is 3 mg of ketoprofen/kg bodyweight
equivalent to 0.03 ml of KetoProPig 10% Oral Solution per kg bodyweight.
Duration of treatment: 1 day. Based on the risk-benefit assessment of the
veterinarian additional administration for another 1-2 days at the most can
be considered; see also 4.4 and 4.6 .
The water intake of the pigs to be treated should be measured before
calculating the total amount of product to be administered each day.
The following calculation should be made to determine the quantity of
KetoProPig 100 mg/ml Oral Solution in ml to be added to the daily
consumption of drinking water:
0.03 ml KetoProPig 100 mg/ml
/
Average body weight
(kg)
kg bodyweight / dayxof the animals to be
treated
=ml KetoPro Pig 100
mg/ml
/
Average amount of drinking water / animal (l)l of drinking water
To prevent overdosing, pigs should be grouped according to bodyweight
and an average bodyweight estimated as accurately as possible.
Do not use in animals where there is the possibility of gastrointestinal
alterations, ulceration or bleeding in order not to aggravate their situation.
Do not use in dehydrated or hypovolemic or hypotensive animal due to the
potential risk of increased renal toxicity.
Do not administer to swine fattened at extensive or semi-extensive
production farms with access to soil or foreign objects that may damage the
gastric mucosa, or with a high parasite burden, or under a severe stress
situation.
Do not use in animals suffering from cardiac, hepatic, or renal disease.
Do not use where there is evidence of blood dyscrasia.
Revised: October 2013
AN: 01121/2012
Do not use in animals with a history of hypersensitivity to ketoprofen, aspirin
or any of the excipients.
See also section 4.7
AN: 01121/2012
Feed intake may decrease due to the treatment and the gastric ulcers induced
by the treatment.
In tolerance studies ulcers have been observed in up to 70% of the treated
animals.
Where administration is performed over a 24 hour period, no severe ulcers were
identified. In a punctuated administration of the product (maximal 3 hours for
administration), at least 12% of severe ulcers were identified. Three days after
the cessation of dosing, gastric ulcers generally recover (with some residual
scarring) or are in the process of recovery/cicatrisation.
If serious adverse events such as signs of ulcers or gastrointestinal
haemorrhage occur, use of the product should be stopped and the advice of a
veterinarian should be sought.
intake. Individual animal medication, preferably by injection, will be required
if daily water intake is insufficient.
Special precautions for use in animals
As ketoprofen may provoke gastrointestinal ulcerations, the use is not
recommended in cases of PMWS (post-weaning multisystemic wasting
syndrome) because ulcers are already frequently associated with this
pathology.
To reduce the risk of adverse reactions do not exceed the recommended
dose or duration of treatment.
When administering to very young animals it is necessary to adjust the dose
accurately as well as to perform a close clinical follow-up.
To reduce the risk of ulceration treatment should be administered over 24
hours. For safety reasons the maximum treatment duration should not exceed
3 days. If side effects occur treatment must be stopped and the advice of a
veterinarian should be sought. Treatment must be suspended for the whole
group.
Avoid use in animals with hypoproteinemia due to the increased risk of
toxicity caused by the highly plasma protein bound nature of ketoprofen,
which may result in toxic effects due to the unbound fraction of the drug.
Special precautions to be taken by the person administering the veterinary
medicinal product to animals
-
glasses should be worn when mixing the veterinary medicinal product.
-
washed immediately with soap and water.
-
running water immediately. Seek medical advice if irritation persists.
-
should be washed off immediately. Wash hands after use.
-
known hypersensitivity to the active substance should avoid contact with the
veterinary medicinal product.
Interactions between Ketoprofen and the most commonly used antibiotics
have not been investigated.
Pre-treatment with other anti-inflammatory substances may result in
additional or increased adverse effects. Do not administer corticosteroids or
other NSAIDs concurrently or within 24 hours of each other. The treatment-
free period, however, should take into account the pharmacological
properties of the products used previously the product must not be
administered in conjunction with other NSAIDs or glucocorticosteroids.
Gastrointestinal tract ulceration may be exacerbated by corticosteroids in
animals given non-steroidal anti-inflammatory drugs. The concomitant
administration of active substances that are highly plasma protein bound
may demonstrate a competitive effect with the ketoprofen with the possibility
of consequent toxic effects due to the unbound fraction of the drug.
Avoid combining with anticoagulant drugs, particularly coumarin derivatives
such as warfarin.
Concurrent use with diuretics or potentially nephrotoxic drugs has a higher
risk to develop renal disturbances secondary to the diminishing blood flow
caused by the inhibition of prostaglandins.
5.
This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.
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Other Products Containing Ketoprofen
These products share the same active ingredient and may be suitable alternatives. Always consult your vet.
Curacef Duo, 50 mg/ml / 150 mg/ml, Suspension for Injection for Cattle
POM-VVirbac
Curacef Duo, 50 mg/ml + 150 mg/ml Suspension for Injection for Cattle
POM-VVirbac
Dinalgen 150 mg/ml Solution for Injection for Cattle, Pigs and Horses
POM-VEcuphar Veterinaria S.L.U.
Draxxin Plus 100 mg/ml + 120 mg/ml Solution for Injection for Cattle
POM-VZoetis UK Limited
Draxxin Plus 100 mg/ml + 120 mg/ml Solution for Injection for Cattle
POM-VZoetis Belgium S.A.
Kelaprofen 100 mg/ml Solution for Injection for Cattle, Horses and Pigs
POM-VKela nv
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