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AVM-GSL Over the Counter Companion Animal

Johnson's 4Fleas 11.4 mg Tablets for Small Dogs and Puppies

Active ingredient: Nitenpyram

Form

Tablet

Species

Dogs

Manufacturer

Elanco Europe Ltd

VMD MA No.

00879/5076

What it's used for

Treatment of flea infestations (C. felis) on dogs.

Full indications, dosage and side effects ↓
View official SPC (PDF)

The prescription itself has a price. See what practices near you charge for a consultation and the written prescription fee.

Paying less for Nitenpyram

  1. 1

    Ask your vet for a written prescription

    They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.

  2. 2

    Fill it at a registered online retailer

    The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

Clinical information

Johnson's 4Fleas 11.4 mg Tablets for Small Dogs and Puppies — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 26 Mar 2026.

Treatment of flea infestations (C. felis) on dogs.
The minimum effective recommended dose is 1 mg/kg, with the following
recommendations:
One Johnson’s 4Fleas11.4mg tablet should be given to small dogs weighing 1 kg to
11.0 kg when a flea infestation is detected. The frequency of treatment depends on
the degree of infestation. In the case of a severe flea infestation, it may be necessary
to treat the animals every day or every other day, until the flea infestation is
controlled. Treatment may be resumed if fleas reappear. No more than one treatment
should be given per day.
Tablets should be given orally, with or without food. In order to improve palatability,
tablets can be disguised in a small quantity of food immediately prior to
administration.

Revised: December 2025
MA split from NI Expiry following AN: 02129/2025
Johnson’s 4Fleas tablets do not have persistent activity. To prevent re-infestation, a
suitable treatment to control immature stages of the flea life cycle is recommended.
The veterinary surgeon should establish an appropriate treatment regime.
None.
For the first hour after administration, the pet may scratch more than normal. This
effect is caused by the fleas reacting to the product. In very rare cases this may
present as transient signs of hyperactivity, panting, vocalization and excessive
grooming/ licking.
Transient neurological signs such as muscle tremors, ataxia and convulsions have
also been reported in very rare occasions.
The frequency of adverse reactions is defined using the following convention:
- very common (more than 1 in 10 animals displaying adverse reaction(s) during the
course of one treatment)
- common (more than 1 but less than 10 animals in 100 animals)
- uncommon (more than 1 but less than 10 animals in 1,000 animals )
- rare (more than 1 but less than 10 animals in 10,000 animals)
- very rare (less than 1 animal in 10,000 animals, including isolated reports).
None.

i) Special precautions for use in animals
Do not use on animals less than 4 weeks old or weighing less than 1kg as
these groups of animals were not studied.

Revised: December 2025
MA split from NI Expiry following AN: 02129/2025
ii) Special precautions to be taken by the person administering the
veterinary medicinal product to animals
None.
None known. No adverse drug reactions were seen in clinical studies when
nitenpyram was administered with other veterinary medicinal products including
commonly used flea products, anthelmintics, vaccines or antibiotics.
Do not store above 25°C.
Not applicable.
5.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.

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