POM-V
Prescription Required
Companion Animal
Imoxat 40 mg + 4 mg Spot-on Solution for Small Cats and Ferrets
Active ingredients: Imidacloprid, Moxidectin
Form
Spot-on
Species
Cats
Ferrets
Manufacturer
Chanelle Pharmaceuticals Manufacturing Ltd
VMD MA No.
08749/5028
What it's used for
aerophila) (adults), AN: 03610/2024Page 2 of 11 • the prevention of lungworm disease (L3/L4 larvae of Aelurostrongylus abstrusus), • the treatment of the l...
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Clinical information
Imoxat 40 mg + 4 mg Spot-on Solution for Small Cats and Ferrets — SPC Details
Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.
aerophila) (adults),
AN: 03610/2024Page 2 of 11
• the prevention of lungworm disease (L3/L4 larvae of Aelurostrongylus
abstrusus),
• the treatment of the lungworm Aelurostrongylus abstrusus
• the treatment of the eye worm Thelazia callipaeda
• the prevention of heartworm disease (L3 and L4 larvae of Dirofilaria
immitis),
• the treatment of infections with gastrointestinal nematodes (L4 larvae,
immature adults and adults of Toxocara cati and
tubaeforme
The veterinary medicinal product can be used as part of a treatment strategy for flea
allergy dermatitis (FAD).
For ferrets
Ctenocephalides felis
Dirofilaria immitis).
AN: 03610/2024Page 2 of 11
• the prevention of lungworm disease (L3/L4 larvae of Aelurostrongylus
abstrusus),
• the treatment of the lungworm Aelurostrongylus abstrusus
• the treatment of the eye worm Thelazia callipaeda
• the prevention of heartworm disease (L3 and L4 larvae of Dirofilaria
immitis),
• the treatment of infections with gastrointestinal nematodes (L4 larvae,
immature adults and adults of Toxocara cati and
tubaeforme
The veterinary medicinal product can be used as part of a treatment strategy for flea
allergy dermatitis (FAD).
For ferrets
Ctenocephalides felis
Dirofilaria immitis).
mg/kg bodyweight moxidectin, equivalent to 0.1 ml/kg bodyweight of the veterinary
medicinal product.
The treatment schedule should be based on individual veterinary diagnosis and on
the local epidemiological situation.
Weight of
cat [kg]
Pipette size to be usedVolume
[ml]
Imidacloprid
[mg/kg bw]
Moxidectin [mg/kg bw]≤ 4 kgImoxat for small cats and
ferrets
0.4minimum of
minimum of
Flea treatment and prevention (Ctenocephalides felis)
One treatment prevents future flea infestation for 4 weeks. Existing pupae in the
environment may emerge for 6 weeks or longer after treatment is initiated, depending
AN: 03610/2024Page 6 of 11
upon climatic conditions. Therefore, it may be necessary to combine animal
treatment with environmental treatments aimed at breaking the flea life cycle in the
surroundings. This can result in a more rapid reduction in the household flea
population. The veterinary medicinal product should be administered at monthly
intervals when used as part of a treatment strategy for flea allergy dermatitis.
Treatment of ear mite infestation (Otodectes cynotis)
A single dose of the veterinary medicinal product should be administered. A further
veterinary examination 30 days after treatment is recommended as some animals
may require a second treatment. Do not apply directly to the ear canal.
Treatment of notoedric mange (Notoedres cati)
A single dose of the veterinary medicinal product should be administered.
Treatment of the lungworm Eucoleus aerophilus (syn. Capillaria aerophila) (adults)
A single dose of the veterinary medicinal product should be administered.
Prevention of Aelurostrongylus abstrusus
The veterinary medicinal product should be administered monthly.
Treatment of Aelurostrongylus abstrusus
The veterinary medicinal product should be administered monthly for three
consecutive months.
Treatment of the eye worm Thelazia callipaeda (adults)
A single dose of the veterinary medicinal product should be administered.
Heartworm prevention (Dirofilaria immitis)
Cats in areas endemic for heartworm, or those which have travelled to endemic
areas, may be infected with adult heartworms. Therefore prior to treatment with the
veterinary medicinal product, the advice provided in section 3.5 should be
considered.
For prevention of heartworm disease, the veterinary medicinal product must be
applied at regular monthly intervals during the time of the year when mosquitoes (the
intermediate hosts which carry and transmit heartworm larvae) are present. The
veterinary medicinal product may be administered throughout the year. The first dose
may be given after first possible exposure to mosquitoes, but not more than one
month after this exposure. Treatment should continue at regular monthly intervals
until 1 month after the last exposure to mosquitoes. To establish a treatment routine,
it is recommended that the same day or date be used each month. When replacing
another heartworm preventative product in a heartworm prevention programme, the
first treatment with the veterinary medicinal product must be given within 1 month of
the last dose of the former medication.
In non-endemic areas there should be no risk of cats having heartworm. Therefore,
they can be treated without special precautions.
AN: 03610/2024Page 7 of 11
Roundworm and hookworm treatment (Toxocara cati and Ancylostoma tubaeforme)
In areas endemic for heartworm, monthly treatment may significantly reduce the risk
of re-infection caused by the respective roundworms and hookworms. In areas non-
endemic for heartworm, the product can be used as part of a seasonal prevention
programme against fleas and gastrointestinal nematodes.
Dosage schedule for ferrets:
One pipette of Imoxat spot-on solution for small cats (0.4 ml) should be administered
per animal.
Do not exceed the recommended dose.
The treatment schedule should be based on the local epidemiological situation.
Flea treatment and prevention (Ctenocephalides felis)
One treatment prevents future flea infestation for 3 weeks. Under heavy flea pressure
it may be necessary to repeat administration after 2 weeks.
Heartworm prevention (Dirofilaria immitis)
Ferrets in areas endemic for heartworm, or those which have travelled to endemic
areas, may be infected with adult heartworms. Therefore prior to treatment with the
veterinary medicinal product, the advice provided in section 3.5 should be
considered.
For prevention of heartworm disease, the veterinary medicinal product must be
applied at regular monthly intervals during the time of the year when mosquitoes (the
intermediate hosts which carry and transmit heartworm larvae) are present. The
veterinary medicinal product may be administered throughout the year. The first dose
may be given after first possible exposure to mosquitoes, but not more than one
month after this exposure. Treatment should continue at regular monthly intervals
until 1 month after the last exposure to mosquitoes.
In non-endemic areas there should be no risk of ferrets having heartworm. Therefore
they can be treated without special precautions.
Method of administration
Spot-on use.
For external use only.
Remove one pipette from the package. Tap the narrow part of the pipette to ensure
the contents are within the main body of the pipette. Snap back the tip of the pipette
to enable the contents to be expelled.
Part the fur on the animal's neck at the base of the skull until the skin is visible. Place
the tip of the pipette on the skin and squeeze the pipette firmly several times to empty
AN: 03610/2024Page 8 of 11
its contents directly onto the skin. Application at the base of the skull will minimise the
opportunity for the animal to lick the product. Apply only to undamaged skin.
medicinal product.
The treatment schedule should be based on individual veterinary diagnosis and on
the local epidemiological situation.
Weight of
cat [kg]
Pipette size to be usedVolume
[ml]
Imidacloprid
[mg/kg bw]
Moxidectin [mg/kg bw]≤ 4 kgImoxat for small cats and
ferrets
0.4minimum of
minimum of
Flea treatment and prevention (Ctenocephalides felis)
One treatment prevents future flea infestation for 4 weeks. Existing pupae in the
environment may emerge for 6 weeks or longer after treatment is initiated, depending
AN: 03610/2024Page 6 of 11
upon climatic conditions. Therefore, it may be necessary to combine animal
treatment with environmental treatments aimed at breaking the flea life cycle in the
surroundings. This can result in a more rapid reduction in the household flea
population. The veterinary medicinal product should be administered at monthly
intervals when used as part of a treatment strategy for flea allergy dermatitis.
Treatment of ear mite infestation (Otodectes cynotis)
A single dose of the veterinary medicinal product should be administered. A further
veterinary examination 30 days after treatment is recommended as some animals
may require a second treatment. Do not apply directly to the ear canal.
Treatment of notoedric mange (Notoedres cati)
A single dose of the veterinary medicinal product should be administered.
Treatment of the lungworm Eucoleus aerophilus (syn. Capillaria aerophila) (adults)
A single dose of the veterinary medicinal product should be administered.
Prevention of Aelurostrongylus abstrusus
The veterinary medicinal product should be administered monthly.
Treatment of Aelurostrongylus abstrusus
The veterinary medicinal product should be administered monthly for three
consecutive months.
Treatment of the eye worm Thelazia callipaeda (adults)
A single dose of the veterinary medicinal product should be administered.
Heartworm prevention (Dirofilaria immitis)
Cats in areas endemic for heartworm, or those which have travelled to endemic
areas, may be infected with adult heartworms. Therefore prior to treatment with the
veterinary medicinal product, the advice provided in section 3.5 should be
considered.
For prevention of heartworm disease, the veterinary medicinal product must be
applied at regular monthly intervals during the time of the year when mosquitoes (the
intermediate hosts which carry and transmit heartworm larvae) are present. The
veterinary medicinal product may be administered throughout the year. The first dose
may be given after first possible exposure to mosquitoes, but not more than one
month after this exposure. Treatment should continue at regular monthly intervals
until 1 month after the last exposure to mosquitoes. To establish a treatment routine,
it is recommended that the same day or date be used each month. When replacing
another heartworm preventative product in a heartworm prevention programme, the
first treatment with the veterinary medicinal product must be given within 1 month of
the last dose of the former medication.
In non-endemic areas there should be no risk of cats having heartworm. Therefore,
they can be treated without special precautions.
AN: 03610/2024Page 7 of 11
Roundworm and hookworm treatment (Toxocara cati and Ancylostoma tubaeforme)
In areas endemic for heartworm, monthly treatment may significantly reduce the risk
of re-infection caused by the respective roundworms and hookworms. In areas non-
endemic for heartworm, the product can be used as part of a seasonal prevention
programme against fleas and gastrointestinal nematodes.
Dosage schedule for ferrets:
One pipette of Imoxat spot-on solution for small cats (0.4 ml) should be administered
per animal.
Do not exceed the recommended dose.
The treatment schedule should be based on the local epidemiological situation.
Flea treatment and prevention (Ctenocephalides felis)
One treatment prevents future flea infestation for 3 weeks. Under heavy flea pressure
it may be necessary to repeat administration after 2 weeks.
Heartworm prevention (Dirofilaria immitis)
Ferrets in areas endemic for heartworm, or those which have travelled to endemic
areas, may be infected with adult heartworms. Therefore prior to treatment with the
veterinary medicinal product, the advice provided in section 3.5 should be
considered.
For prevention of heartworm disease, the veterinary medicinal product must be
applied at regular monthly intervals during the time of the year when mosquitoes (the
intermediate hosts which carry and transmit heartworm larvae) are present. The
veterinary medicinal product may be administered throughout the year. The first dose
may be given after first possible exposure to mosquitoes, but not more than one
month after this exposure. Treatment should continue at regular monthly intervals
until 1 month after the last exposure to mosquitoes.
In non-endemic areas there should be no risk of ferrets having heartworm. Therefore
they can be treated without special precautions.
Method of administration
Spot-on use.
For external use only.
Remove one pipette from the package. Tap the narrow part of the pipette to ensure
the contents are within the main body of the pipette. Snap back the tip of the pipette
to enable the contents to be expelled.
Part the fur on the animal's neck at the base of the skull until the skin is visible. Place
the tip of the pipette on the skin and squeeze the pipette firmly several times to empty
AN: 03610/2024Page 8 of 11
its contents directly onto the skin. Application at the base of the skull will minimise the
opportunity for the animal to lick the product. Apply only to undamaged skin.
Do not use in kittens under 9 weeks of age.
Do not use in case of hypersensitivity to the active substances or to any of the
excipients.
For ferrets: do not use Imoxat for large cats (0.8 ml) or Imoxat for dogs (any size).
For dogs, the corresponding “Imoxat for dog” product, which contains 100 mg/ml
imidacloprid and 25 mg/ml moxidectin, must be used.
Do not use on canaries.
Do not use in case of hypersensitivity to the active substances or to any of the
excipients.
For ferrets: do not use Imoxat for large cats (0.8 ml) or Imoxat for dogs (any size).
For dogs, the corresponding “Imoxat for dog” product, which contains 100 mg/ml
imidacloprid and 25 mg/ml moxidectin, must be used.
Do not use on canaries.
{Cats and ferrets}
Rare
(1 to 10 animals / 10000
animals treated):
Application site greasy fur
Vomiting
Hypersensitivity reactions (local)
Erythema
Very rare
(<1 animal / 10000 animals
treated, including isolated
reports):
Behavioural disorder (e.g. agitation)
Hypersalivation
3,4
Neurological signs
Pruritus
Lethargy
and inappetence
AN: 03610/2024Page 5 of 11
: These signs disappear without further treatment.
: Transiently noted and related to sensation at application site.
: If the animal licks the application site after treatment, (most of which are transient).
: The veterinary medicinal product tastes bitter. Salivation may occasionally occur if
the animal licks the application site immediately after treatment. This is not a sign of
intoxication and disappears within some minutes without treatment. Correct
application will minimise licking of the application site.
: Transient in Cats
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder or its local representative or the national
competent authority via the national reporting system. See the package leaflet for
respective contact details.
Rare
(1 to 10 animals / 10000
animals treated):
Application site greasy fur
Vomiting
Hypersensitivity reactions (local)
Erythema
Very rare
(<1 animal / 10000 animals
treated, including isolated
reports):
Behavioural disorder (e.g. agitation)
Hypersalivation
3,4
Neurological signs
Pruritus
Lethargy
and inappetence
AN: 03610/2024Page 5 of 11
: These signs disappear without further treatment.
: Transiently noted and related to sensation at application site.
: If the animal licks the application site after treatment, (most of which are transient).
: The veterinary medicinal product tastes bitter. Salivation may occasionally occur if
the animal licks the application site immediately after treatment. This is not a sign of
intoxication and disappears within some minutes without treatment. Correct
application will minimise licking of the application site.
: Transient in Cats
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder or its local representative or the national
competent authority via the national reporting system. See the package leaflet for
respective contact details.
Please refer to section
Special precautions for safe use in the target species:
The treatment of cats weighing less than 1 kg and ferrets weighing less than 0.8 kg
should be based on a benefit-risk assessment.
There is limited experience on the use of the veterinary medicinal product in sick and
debilitated animals, thus the veterinary medicinal product should only be used based
on a benefit-risk assessment for these animals.
Do not apply in the mouth, in the eyes or the ears of the animal.
Care should be taken that the veterinary medicinal product is not ingested by animals
and does not come into contact with the eyes or mouth of the recipient and/or other
animals.
Consider carefully the correct application method described in section 3.9, especially
that the veterinary medicinal product should be applied to the site specified in order
to minimise the risk for the animal to lick the veterinary medicinal product.
Do not allow recently treated animals to groom each other. Do not allow treated
animals to come into contact with untreated animals until the application site is dry.
In case of accidental oral uptake, symptomatic treatment should be administered.
There is no known specific antidote. The use of activated charcoal may be beneficial.
It is recommended that cats and ferrets living in, or travelling to areas endemic for
heartworm are treated monthly with the veterinary medicinal product to protect them
from heartworm disease.
Whilst the accuracy of diagnosis of heartworm infection is limited, it is recommended
that attempts be made to check the heartworm status of any cat and ferret aged over
6 months, before beginning prophylactic treatment, as use of the veterinary medicinal
product on cats or ferrets which have adult heartworms may cause serious adverse
effects, including death. If adult heartworm infection is diagnosed, the infection
should be treated in accordance with current scientific knowledge.
In certain individual cats Notoedres cati infestation may be severe. In these severe
cases concomitant supportive treatment is necessary as treatment with the veterinary
medicinal product alone may not be sufficient to prevent death of the animal.
Imidacloprid is toxic for birds, especially canaries.
AN: 03610/2024Page 4 of 11
Special precautions to be taken by the person administering the veterinary medicinal
product to animals
Avoid contact with skin, eyes or mouth.
Do not eat, drink or smoke during application.
Wash hands thoroughly after use.
After application do not stroke or groom animals until the application site is dry.
In case of accidental spillage onto skin, wash off immediately with soap and water.
People with known hypersensitivity to benzyl alcohol, imidacloprid or moxidectin
should administer the veterinary medicinal product with caution. In very rare cases
the veterinary medicinal product may cause skin sensitisation or transient skin
reactions (for example numbness, irritation or burning/tingling sensation).
In very rare cases the veterinary medicinal product may cause respiratory irritation in
sensitive individuals.
If the veterinary medicinal product accidentally gets into eyes, they should be
thoroughly flushed with water.
If skin or eye symptoms persist, or the veterinary medicinal product is accidentally
swallowed, seek medical advice immediately and show the package leaflet or the
label to the physician.
Special precautions for the protection of the environment:
None.
Other precautions:
The solvent in the veterinary medicinal product may stain or damage certain materials
including leather, fabrics, plastics and finished surfaces. Allow the application site to
dry before permitting contact with such materials.
Special precautions for safe use in the target species:
The treatment of cats weighing less than 1 kg and ferrets weighing less than 0.8 kg
should be based on a benefit-risk assessment.
There is limited experience on the use of the veterinary medicinal product in sick and
debilitated animals, thus the veterinary medicinal product should only be used based
on a benefit-risk assessment for these animals.
Do not apply in the mouth, in the eyes or the ears of the animal.
Care should be taken that the veterinary medicinal product is not ingested by animals
and does not come into contact with the eyes or mouth of the recipient and/or other
animals.
Consider carefully the correct application method described in section 3.9, especially
that the veterinary medicinal product should be applied to the site specified in order
to minimise the risk for the animal to lick the veterinary medicinal product.
Do not allow recently treated animals to groom each other. Do not allow treated
animals to come into contact with untreated animals until the application site is dry.
In case of accidental oral uptake, symptomatic treatment should be administered.
There is no known specific antidote. The use of activated charcoal may be beneficial.
It is recommended that cats and ferrets living in, or travelling to areas endemic for
heartworm are treated monthly with the veterinary medicinal product to protect them
from heartworm disease.
Whilst the accuracy of diagnosis of heartworm infection is limited, it is recommended
that attempts be made to check the heartworm status of any cat and ferret aged over
6 months, before beginning prophylactic treatment, as use of the veterinary medicinal
product on cats or ferrets which have adult heartworms may cause serious adverse
effects, including death. If adult heartworm infection is diagnosed, the infection
should be treated in accordance with current scientific knowledge.
In certain individual cats Notoedres cati infestation may be severe. In these severe
cases concomitant supportive treatment is necessary as treatment with the veterinary
medicinal product alone may not be sufficient to prevent death of the animal.
Imidacloprid is toxic for birds, especially canaries.
AN: 03610/2024Page 4 of 11
Special precautions to be taken by the person administering the veterinary medicinal
product to animals
Avoid contact with skin, eyes or mouth.
Do not eat, drink or smoke during application.
Wash hands thoroughly after use.
After application do not stroke or groom animals until the application site is dry.
In case of accidental spillage onto skin, wash off immediately with soap and water.
People with known hypersensitivity to benzyl alcohol, imidacloprid or moxidectin
should administer the veterinary medicinal product with caution. In very rare cases
the veterinary medicinal product may cause skin sensitisation or transient skin
reactions (for example numbness, irritation or burning/tingling sensation).
In very rare cases the veterinary medicinal product may cause respiratory irritation in
sensitive individuals.
If the veterinary medicinal product accidentally gets into eyes, they should be
thoroughly flushed with water.
If skin or eye symptoms persist, or the veterinary medicinal product is accidentally
swallowed, seek medical advice immediately and show the package leaflet or the
label to the physician.
Special precautions for the protection of the environment:
None.
Other precautions:
The solvent in the veterinary medicinal product may stain or damage certain materials
including leather, fabrics, plastics and finished surfaces. Allow the application site to
dry before permitting contact with such materials.
During treatment with the veterinary medicinal product no other antiparasitic
macrocyclic lactone should be administered.
No interactions between the veterinary medicinal product and routinely used
veterinary medicinal products or medical or surgical procedures have been observed.
macrocyclic lactone should be administered.
No interactions between the veterinary medicinal product and routinely used
veterinary medicinal products or medical or surgical procedures have been observed.
Store in the original package in order to protect from light and moisture.
Do not store above 25°C.
Do not store above 25°C.
Not applicable
This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.
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