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POM-V Prescription Required

Hyogen Emulsion for Injection for Pigs

Active ingredient: Mycoplasma hyopneumoniae

Form

Injection

Species

Pigs

Manufacturer

Ceva Sante Animale

VMD MA No.

14966/5050

What it's used for

For the active immunisation of fattening pigs from 3 weeks of age to reduce the occurrence and severity of lung lesions caused by infection. Onset of immun...

Full indications, dosage and side effects ↓
View official SPC (PDF)

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Paying less for Mycoplasma hyopneumoniae

  1. 1

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    They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.

  2. 2

    Fill it at a registered online retailer

    The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Hyogen Emulsion for Injection for Pigs — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 26 Mar 2026.

For the active immunisation of fattening pigs from 3 weeks of age to reduce the
occurrence and severity of lung lesions caused by
infection.
Onset of immunity: 3 weeks
Duration of immunity: 26 weeks
None.
Target species:
Pigs for fattening
Very common
(>1 animal / 10 animals
treated):
Elevated temperature*
Injection site swelling**
Uncommon
(1 to 10 animals / 1,000
animals treated):
Hypersensitivity reaction***
Vomiting***
Very rare
(<1 animal / 10,000
animals treated, including
isolated reports):
Anaphylactic shock****
Recumbency****
*On the day of vaccination a transient mean increase in body temperature of
about 1.3oC is very common. In an individual pig this increase might reach 2oC,
but in all cases body temperature is back to normal the next day.
** A local reaction at the site of injection in the form of a swelling of a diameter
up to 5 cm can be very common, which can last for three days. These reactions
are of transient nature and do not need further treatment.
*** Immediate mild hypersensitivity-like reactions may occur uncommonly after
vaccination, resulting in transient clinical signs such as vomiting.
**** Serious anaphylactic-type reactions (shock, recumbency) which may be
fatal have been reported very rarely. Such reactions require prompt
symptomatic treatment.
Reporting adverse events is important. It allows continuous safety monitoring of
a veterinary medicinal product. Reports should be sent, preferably via a
veterinarian, to either the marketing authorisation holder or its local
representative or the national competent authority via the national reporting
system. See also the last section of the package leaflet for respective contact
details.
Vaccinate healthy animals only.

Revised: October 2025
AN: 01772/2025
The data available are not sufficient to exclude the interaction of maternally
derived antibodies against Mycoplasma hyopneumoniae with vaccine uptake.
Interaction with maternally derived antibodies is known and should be taken into
consideration. It is recommended to delay vaccination in piglets with residual
MDA against at the age of 3 weeks.

Special precautions for use in animals:
Not applicable.
Special precautions to be take by the person administering the veterinary
medicinal product to animals:
In case of accidental self-injection, seek medical advice immediately and show
the package leaflet or the label to the physician.
To the user:
This veterinary medicinal product contains mineral oil. Accidental injection/self-
injection may result in severe pain and swelling, particularly if injected into a
joint or finger, and in rare cases could result in the loss of the affected finger if
prompt medical attention is not given. If you are accidentally injected with this
veterinary medicinal product, seek prompt medical advice even if only a very
small amount is injected and take the package leaflet with you. If pain persists
for more than 12 hours after medical examination, seek medical advice again.
To the physician:
This veterinary medicinal product contains mineral oil. Even if small amounts
have been injected, accidental injection with this product can cause intense
swelling, which may, for example, result in ischaemic necrosis and even the
loss of a digit. Expert and PROMPT surgical attention is required and may
necessitate early incision and irrigation of the injected area, especially where
there is involvement of finger pulp or tendon.
Special precautions for the protection of the environment:
Not applicable.
Other precautions

Revised: October 2025
AN: 01772/2025
Safety and efficacy data are available which demonstrate that this vaccine can
be mixed with Circovac and administered to piglets at one injection site.
Vaccinate piglets from 3 weeks of age.
Onset of immunity: 3 weeks after vaccination when mixed with Circovac
Duration of immunity: 23 weeks when mixed with Circovac.

Revised: October 2025
AN: 01772/2025
In case of mixing with Circovac, slight and transient local reactions may occur
very commonly after the administration, mainly swelling (0.5 cm - 5 cm), mild
pain and redness as well as in some cases oedema. These reactions resolve
spontaneously within maximum 4 days. Transient lethargy may occur very
commonly on the day of vaccination which resolves spontaneously within 1-2
days. An increase in individual rectal temperature of up to 2.5°C may occur
commonly lasting less than 24 hours. The above adverse reactions were
observed in clinical studies.
The product literature of Circovac should be consulted before mixed
administration.
No information is available on the safety and efficacy of this vaccine when used
with any other veterinary medicinal product, except when mixed with Circovac.
A decision to use this vaccine before or after any other veterinary medicinal
product therefore needs to be made on a case by case basis.
Store and transport refrigerated (2￿C – 8￿C).
Do not freeze.
Protect from light.
Zero days.
5. IMMUNOLOGICAL PROPERTIES
Pharmacotherapeutic group: Pig / Inactivated bacterial vaccines /
mycoplasma
ATCvet code: QI09AB13
Inactivated bacterial vaccine, containing whole cell concentrate of Mycoplasma
hyopneumoniae strain 2940. This antigen is incorporated in an adjuvant for
stimulation of immunity, based on a combination of light liquid paraffin and cell
free Escherichia coli J5 LPS. The product stimulates the development of active
immunity in pigs against Mycoplasma hyopneumoniae
Under experimental conditions reduction of M. hyopneumoniae colonisation was
demonstrated 44-50 days post vaccination.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.

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