POM-V Prescription Required

Gabbrovet 140 mg/ml Solution for Use in Drinking Water / Milk for Pre-ruminant Cattle and Pigs

Active ingredient: Paromomycin Sulfate

Form

Solution

Species

Cattle Pigs

Manufacturer

Ceva Sante Animale

VMD MA No.

14966/3092

What it's used for

Treatment of gastro-intestinal infections caused by paromomycin.

Full indications, dosage and side effects ↓

View official SPC (PDF)

The prescription itself has a price. See what practices near you charge for a consultation and the written prescription fee.

Paying less for Paromomycin Sulfate

1

Ask your vet for a written prescription

They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.
2

Fill it at a registered online retailer

The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

Your prescription rights → VMD register of retailers →

Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Gabbrovet 140 mg/ml Solution for Use in Drinking Water / Milk for Pre-ruminant Cattle and Pigs — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 26 Mar 2026.

Treatment of gastro-intestinal infections caused by
paromomycin.

Oral use.
Pre-ruminant cattle: administration in milk/milk replacer.
Pigs: administration in drinking water.
Duration of treatment: 3-5 days.
Pre-ruminant cattle 1.25 – 2.5 ml of product/10 kg BW/day, equivalent to 17500 -
35000 IU of paromomycin per kg BW/day (i.e. approximately 25-50 mg
paromomycin sulfate per kg BW/day).

Pigs: 1.25 – 2 ml of product/10 kg BW/day, equivalent to 17500 - 28000 IU of
paromomycin per kg BW/day (i.e. approximately 25-40 mg paromomycin sulfate
per kg BW/day).
For the administration through the drinking water the exact daily amount of product
should be based on the number of the animals to be treated, and the
recommended dose calculated according to the following formula:
ml product/ kg BW/day x Mean bodyweight (kg)
of animals to be treated ml product per
litre
_ = drinking
water/day/ animal/
Mean daily water consumption (litre) per animal

Revised: November 2025
AN: 01790/2025Page 4 of 6
To ensure a correct dosage bodyweight should be determined as accurately as
possible.
The uptake of medicated water depends on several factors including clinical
conditions of the animals and the local conditions such as ambient temperature
and humidity. In order to obtain the correct dosage, uptake of drinking water has to
be monitored and the concentration of paromomycin has to be adjusted
accordingly.
Medicated drinking water/milk/milk replacer and any stock solutions should be
freshly prepared every 6 hours (in milk/milk replacer) or every 24 hours (in water).

Do not use in animals with known hypersensitivity to paromomycin, other
aminoglycosides or any of the excipients.
Do not use in cases with impaired function of the kidneys or liver.
Do not use in ruminating animals.
Do not use in turkeys due to the risk of selection for antimicrobial resistance in
intestinal bacteria.

In rare occasions soft faeces has been observed.
The frequency of adverse reactions is defined using the following convention:
- very common (more than 1 in 10 animals treated displaying adverse reaction(s))
- common (more than 1 but less than 10 animals in 100 animals treated)
- uncommon (more than 1 but less than 10 animals in 1,000 animals treated)
- rare (more than 1 but less than 10 animals in 10,000 animals treated)
- very rare (less than 1 animal in 10,000 animals treated, including isolated
reports)
Aminoglycoside antibiotics such as paromomycin can cause oto- and
nephrotoxicity.

None.

Revised: November 2025
AN: 01790/2025Page 2 of 6

Special precautions for use in animals
The uptake of medication by animals can be altered as a consequence of illness.
In case of insufficient uptake of water/milk animals should be treated parenterally
using a suitable injectable product following the advice of the veterinarian.
The use of the product should be combined with good management practices e.g.
good hygiene, proper ventilation, no overstocking.
Since the product is potentially ototoxic and nephrotoxic, it is recommended to
assess kidney function. Special care should be taken when considering
administration of the product to newborn animals due to the known higher
gastrointestinal absorption of paromomycin in neonates. This higher absorption
could lead to an increased risk of oto-and nephrotoxicity. The use of the product in
neonates should be based on benefit-risk assessment by the responsible
veterinarian.
Prolonged or repeated use of the product should be avoided by improving
management practices and through cleansing and disinfection. Use of the product
should be based on susceptibility testing of the bacteria isolated from the animal. If
this is not possible, therapy should be based on local (regional, farm level)
epidemiological information about susceptibility of the target bacteria. Official,
national and regional antimicrobial policies should be taken into account when the
product is used.
Use of the product deviating from the given instructions may increase the
prevalence of bacteria resistant to paromomycin and may decrease the
effectiveness of treatment with aminoglycosides due to the potential for cross-
resistance.
Aminoglycosides are considered as critical in human medicine. Consequently,
they should not be used as a first intention treatment in veterinary medicine.
Special precautions to be taken by the person administering the veterinary
medicinal product to animals
-
in some people.
-
other aminoglycosides should avoid contact with the product.
-
-
impervious gloves should be worn when handling the product.
-
of water.
-
should seek medical advice and show the physician this warning.
Swelling of the face, lips and eyes or difficulty in breathing are more
serious symptoms and require urgent medical attention.
-
-
immediately and show the label to the physician.
-

Revised: November 2025
AN: 01790/2025Page 3 of 6

General anaesthetics and muscle relaxing products increase the neuro-blocking
effect of aminoglycosides. This may cause paralysis and apnoea.
Do not use concurrently with strong diuretics and potentially oto- or nephrotoxic
substances.

125 ml and 250 ml bottles:
Do not store above 25°C
500 ml and 1000 ml bottles:
No special storage conditions required
All Presentations:
After first opening, keep the bottle tightly closed.

Cattle:
Meat and offal: 20 days
Pigs:
Meat and offal: 3 days
5.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.