POM-V Prescription Required Companion Animal

Fertigest 4 micrograms/ml Solution for Injection

Active ingredient: Buserelin Acetate

Form

Injection

Species

Cattle Horses Pigs Rabbits

Manufacturer

Vetpharma Animal Health, S.L

VMD MA No.

32509/4023

What it's used for

Cattle: - - - insemination at a fixed time together with prostaglandin F2α administration. Horse: - - Pig: - administering a progestagen (gilts) that can b...

Full indications, dosage and side effects ↓

View official SPC (PDF)

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Paying less for Buserelin Acetate

1

Ask your vet for a written prescription

They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.
2

Fill it at a registered online retailer

The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

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Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Fertigest 4 micrograms/ml Solution for Injection — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 26 Mar 2026.

Cattle:
-
-
-
insemination at a fixed time together with prostaglandin F2α administration.
Horse:
-
-
Pig:
-
administering a progestagen (gilts) that can be used as part of a single fixed
time artificial insemination programme.
Rabbit:
-
-

Revised: November 2024
AN: 00788/2024 & 01300/2024

Intramuscular or subcutaneous use.
In cattle, horses and rabbits, the preferred route of administration is intramuscular
injection, but it may also be injected subcutaneously. In pigs, the preferred route of
administration is intramuscular.
Cattle:
-
acetate) per animal.
-
buserelin acetate) per animal, administered between the start of oestrus up to
and including the time of artificial insemination.
-
medicinal product (0.0105 mg of buserelin acetate) per animal. The following
protocol can be applied: 0.0105 mg of buserelin acetate on Day 0, followed by
a prostaglandin injection 7 days later and a second injection of 0.0105 mg of
buserelin acetate 48 hours after the administration of prostaglandin. Fixed-
time artificial insemination can take place 12 to 24 hours after the second
buserelin acetate injection.
Horse:
animal.
The product should be administered on the first day on which the follicle has reached
its maximum size. The product is best given approximately 6 hours prior to service.
The mare should be served again the next morning if she is still in oestrus.

Revised: November 2024
AN: 00788/2024 & 01300/2024
If ovulation has not occurred within 24 hours after treatment, then the injection should
be repeated.
Rabbit: 0.2 ml of veterinary medicinal product (0.00084 mg of buserelin acetate) per
animal.

carried out directly after administration

mating.
Pig:
animal.
The artificial insemination schedule for pigs is the following:
Gilt:
-
of the synchronisation treatment with a progestagen.
-
veterinary medicinal product.
Sow:
-
-
administering the veterinary medicinal product.
In individual cases, the oestrus may still not be visible 30 to 33 hours after treatment
with the veterinary medicinal product. In these cases, insemination may be carried
out at a later time, when signs of heat are present.
The rubber stopper may be safely puncture up to 20 times.

Do not use in animals with known hypersensitivity to the active ingredient or to the
excipients.

None known

Cattle:
Cattle with a short interval between calving and insemination (< 60 days), a low Body
Condition Score or high parity may display a lower pregnancy rate after a standard
synchronisation protocol (see section 4.9). There is no guarantee that all cows that
were synchronised according to the protocol will be in oestrus at the time of artificial
insemination. The chances of conception may be higher if the cow is in oestrus at the
time of insemination.
To maximise conception rates of cows to be treated, the ovarian status should be
determined and regular cyclic ovarian activity confirmed. Optimal results will be
achieved in healthy normally-cycling cows.
Pig:
The buserelin administration is purely zootechnical in nature. Buserelin is
administered after oestrus synchronisation. Buserelin is administered to gilts after
treatment with a progestagen. The consequence of the progestagen treatment is
that, if it is terminated simultaneously, the fertility cycles of treated animals are
synchronised. Oestrus synchronisation is achieved naturally in sows by weaning.
Insemination may be performed 30 to 33 hours after injection. It is recommended that
a boar is present at the time of artificial insemination and the animal should be
checked for signs of heat prior to insemination.
A negative energy balance during lactation could in some cases be associated with
the mobilisation of bodily reserves, with a significant decrease of the thickness of the
back fat (more than approximately 30%). These animals could suffer from delayed
oestrus and ovulation and should be cared for and bred individually.

Special precautions for use in animals
Use aseptic procedures to inject the product. Infection may occur if anaerobic
bacteria penetrate the tissue at the injection site, in particular following intramuscular
injection.
Pigs:
If the recommended time schedule is not carefully followed, fertility may be impaired.
Progestins and buserelin can only be used in healthy animals.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals
Buserelin has been shown to be foetotoxic in laboratory animals; therefore, pregnant
women should not handle the veterinary medicinal product. Women of child-bearing
age should administer the product with caution.
Avoid eye and skin contact with the product. In case of accidental contact, rinse
thoroughly with water. Should skin contact with the product occur, wash the exposed

Revised: November 2024
AN: 00788/2024 & 01300/2024
area immediately with soap and water, as GnRH analogues may be absorbed
through the skin. Wash hands after use.
When administering the product, care should be taken to avoid accidental self-
injection by ensuring that animals are suitably restrained and the application needle
is shielded until the moment of injection. In case of accidental self-injection, seek
medical advice immediately and show the package leaflet or the label to the
physician.
Do not eat, drink or smoke while handling the product.

None known.

Do not store above 25 °C.
Keep the vial in the outer carton in order to protect from light.

Revised: November 2024
AN: 00788/2024 & 01300/2024

Cattle, horse, pig and rabbit
Meat and offal: Zero days.
Cattle and horse
Milk: Zero hours.
5.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.