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AVM-GSL Over the Counter Companion Animal

Eziflea 40 mg Spot-on Solution for Small Cats, Small Pet Rabbits & Small Dogs

Active ingredient: Imidacloprid

Form

Spot-on

Species

Cats Dogs Rabbits

Manufacturer

Chanelle Pharmaceuticals Manufacturing Ltd

VMD MA No.

08749/3133

What it's used for

Treatment of flea infestations in rabbits of less than 4 kg body weight. Fleas are killed within one day following treatment. One treatment prevents furthe...

Full indications, dosage and side effects ↓
View official SPC (PDF)

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Paying less for Imidacloprid

  1. 1

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    They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.

  2. 2

    Fill it at a registered online retailer

    The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

Clinical information

Eziflea 40 mg Spot-on Solution for Small Cats, Small Pet Rabbits & Small Dogs — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

Treatment of flea infestations in rabbits of less than 4 kg body weight.
Fleas are killed within one day following treatment. One treatment prevents further
flea infestation for three to four weeks on cats and up to one week on pet rabbits.
Dogs
For the prevention and treatment of flea infestations and for the treatment of biting
lice on dogs of less than 4 kg body weight.
Fleas on dogs are killed within one day following treatment. One treatment prevents
further flea infestation for four weeks.
should be weighed accurately prior to treatment.
Dosage and Treatment Schedule
Cat/Rabbit/Dog (kg
body weight)
ProductNumber of
Pipettes
Eziflea
(mg/kg body
weight)
Less than 4 kg Eziflea 40 for Small
Cats and Small Pet
Rabbits and Dogs
1 x 0.4 mlminimum of 10
In cases of biting louse infestation, a further veterinary examination 30 days after
treatment is recommended as some animals may require a second treatment.
Method of administration:
Cat and rabbits
Hold the pipette upright. Tap the narrow part of the pipette to ensure the contents
remain within the main body of the pipette. Snap back the tip. Part the hair on the
animal’s neck at the base of the skull until the skin is visible.
Place the tip of the pipette on the skin and squeeze the pipette several times to
empty its contents completely and directly onto the skin in one spot. Correct
application will minimise the opportunity for the animal to lick the product.
Dogs
Hold the pipette upright. Tap the narrow part of the pipette to ensure the contents
remain within the main body of the pipette. Snap back the tip. With the dog in the
standing position, part the coat between the shoulder blades until the skin is visible.
Place the tip of the pipette on the skin and squeeze the pipette several times to
empty its contents completely and directly onto the skin in one spot. Correct
application will minimise the opportunity for the animal to lick the product.
Cats & Pet Rabbits
Do not treat unweaned kittens of less than 8 weeks of age.
Do not use on pet rabbits of less than 10 weeks of age.
Do not use in case of hypersensitivity to the active substance or to any of the
excipients.
Dogs
Do not treat unweaned puppies of less than 8 weeks of age.
Do not use in case of hypersensitivity to the active substance or to any of the
excipients.
Cats:
Very rare
(<1 animal / 10 000 animals treated,
including isolated reports):
Agitation
Diarrhoea
, Hypersalivation
, Vomiting
Neurological signs (e.g. Depression,
Incoordination, Tremor)
Application site reaction (e.g. Hair loss,
Itching, Reddening of the skin, Skin
lesion)
May occur after oral ingestion.
May occur if the cat licks the application site immediately after treatment due to the
bitter taste. This is not a sign of intoxication and disappears within some minutes
without treatment.
Rabbits:
Very rare
(<1 animal / 10 000 animals treated,
including isolated reports):
Agitation
Diarrhoea
, Hypersalivation
Application site reaction (e.g. Hair loss,
Itching, Reddening of the skin, Skin
lesion)
May occur after oral ingestion.
May occur if the cat licks the application site immediately after treatment due to the
bitter taste. This is not a sign of intoxication and disappears within some minutes
without treatment.
Dogs:
Very rare
(<1 animal / 10 000 animals treated,
including isolated reports):
Agitation
Hypersalivation
Disorientation, Neurological signs (e.g.
Depression, Incoordination, Tremor)
Application site reaction (e.g. Hair loss,
Itching, Reddening of the skin, Skin
lesion)
May occur if the dog licks the application site immediately after treatment due to the
bitter taste. This is not a sign of intoxication and disappears within some minutes
without treatment.
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product.
Reports should be sent, preferably via a veterinarian, to either the marketing
authorisation holder or the national competent authority via the national reporting
system. See the package leaflet for respective contact details.
This product is for topical use and should not be administered orally.
Apply only to undamaged skin
Care should be taken to avoid the contents of the pipette coming into contact with the
eyes or mouth of the recipient animal.
Do not allow recently treated animals to groom each other.

Special precautions for safe use in the target species:
If signs of disease persist or appear, consult a veterinary surgeon.
Re-infestation from emergence of new fleas in the environment may continue to
occur for six weeks or longer after treatment is initiated. More than one treatment
may therefore be required, depending on the level of fleas in the environment. To aid
reduction in environmental challenge, the additional use of a suitable environmental
treatment against adult fleas and their developing stages is recommended. In order
to reduce further the environmental challenge, it is recommended that all cats, dogs
and rabbits in the household are treated.
The product remains effective if the animal becomes wet, for example after exposure
to heavy rain.
However, re-treatment may become necessary, depending on the presence of fleas
in the environment. In these cases do not treat more frequently than once weekly.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals:
This product can cause mucous membrane, skin and eye irritation.
Therefore, contact of the product with mouth, skin and eyes should be avoided.
This product contains benzyl alcohol and may cause skin sensitisation or transient
skin reactions in rare cases (for example, irritation, tingling).
People with a known hypersensitivity (allergy) to insecticides or alcohol should avoid
contact with the product.
Do not smoke, drink or eat during application.
If contact with the skin occurs, wash hands with soap and water.
If the product gets into eyes, the eyes should be thoroughly rinsed with clean water. If
skin or eye irritation persists, or the product is accidentally swallowed, seek medical
advice.
Do not stroke, groom or play with treated animals until the application site is dry. It is
therefore recommended that animals are not treated during the day, but should be
treated during the early evening, and that recently treated animals are not allowed to
sleep with owners, especially children.
Dispose of used pipettes immediately.
Wash hands after use.
Special precautions for the protection of the environment:
Imidacloprid is toxic to aquatic organisms. To avoid adverse effects on aquatic
organisms, treated dogs should not be allowed to enter surface water for 48 hours
after treatment.
Other precautions:
The solvent in this product may stain certain materials including leather, fabrics,
plastics and finished surfaces. Allow the application site to dry before permitting
contact with such materials.
Do not use simultaneously with other flea products which are applied directly onto the
animal.
This veterinary medicinal product does not require any special storage conditions.
Do not use on rabbits intended for human consumption.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.

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