Exzolt 10 mg/ml Solution for Use in Drinking Water for Chickens

For use in drinking water.
The dose is 0.5 mg fluralaner per kg body weight (equivalent to 0.05 ml of product)
administered twice, 7 days apart. The complete course of treatment must be
administered for a full therapeutic effect.

Revised: October 2024
AN: 00688/2024
If another course of treatment is indicated, the interval between two courses of
treatment should be at least 3 months.
Determine the duration of time (between 4 and 24 hours) over which to administer
the medicated water on the treatment day. This period of time must be long enough
to allow all the birds to receive the required dose. Estimate how much water birds will
consume during treatment based on the previous day’s water consumption. The
product should be added to a volume of water that the chickens will consume in one
day. No other source of drinking water should be available during the medication
period.
Calculate the volume of product needed based on the total weight of all birds in the
house to be treated. To ensure administration of the correct dose, the body weight
should be determined as accurately as possible, and an accurate measuring device
should be used for measuring the calculated volume of the product to be
administered.
The required volume of product for each treatment day is calculated from the total
body weight (kg) of the entire group of chickens to be treated:
Volume of product (ml) per treatment day = Total body weight (kg) of chickens
to be treated x 0.05 ml/kg
Therefore:
500 ml of product treats 10,000 kg body weight (e.g., 5,000 chickens of 2 kg body
weight each).
or 1 ml of product treats 20 kg body weight (e.g., 10 chickens of 2 kg body weight
each).
The instructions below need to be followed, in the order described, to prepare the
medicated water.
For large poultry farms using 1-litre or 4-litre bottles of the veterinary medicinal
product:
Check the water system to ensure it works properly and is free of leaks; also ensure
that water is available to all nipple or bell drinkers.
For each day of treatment, medicated water must be freshly prepared.
Mix the required volume of the product with water into a large medication tank or
create a stock solution in a small container. The stock solution must be further diluted
with drinking water and administered over time, using a proportioner or dosing pump.
Always add product and water simultaneously in order to avoid foaming. It is
important to rinse the measuring device used to measure the required product
volume during the filling phase in order to ensure that the complete dose is emptied
into the medication tank or the stock solution and that no residues remain in the
measuring device.
Stir the stock solution or the content of the medication tank gently until the medicated
water is homogeneous. Connect the medication tank or the proportioner or dosing
pump to the drinking water system.

Revised: October 2024
AN: 00688/2024
Make sure the dosing pump is properly set to deliver the medicated water during the
predetermined treatment period (hours).
Prime the drinker lines with medicated water and check to see when medicated water
has reached the end of the line. This procedure should be repeated on each day of
administration.
After each treatment administration, fill the stock solution container with clean
(unmedicated) water to rinse the water lines.
For small poultry farms using 4-ml or 50-ml bottles of the veterinary medicinal
product:
Check that the water system functions properly and is free of leaks.
For each day of treatment, medicated water must be freshly prepared.
Mix the required volume of the product with the determined amount of water in a
measuring device.
Add product and water simultaneously in order to avoid foaming.
Stir stock solution gently but thoroughly until the medicated water is homogeneous.
It is important to rinse the measuring device to ensure that the complete dose is
provided to the chickens and that no residues remain. Add the rinse water to the
drinkers.
Ensure that medicated water is evenly divided to all drinkers.
At time of initial use, remove the original cap from the bottle and discard it. Twist on
the in-use cap provided in the carton box. Doing so will permanently insert the
syringe adaptor into the neck of the bottle.
To dose:
Remove the in-use cap.
Attach a 1-ml dosing syringe to the bottle by gently pushing the end of the syringe
into the syringe adapter.
Turn the bottle/syringe upside down. Pull down on the plunger to withdraw the correct
dose volume. If any air bubbles are seen in the syringe, push them out and pull down
again on the plunger until the correct volume is withdrawn.
Turn the bottle/syringe upright. Remove the syringe from the syringe adaptor.
Replace the in-use cap.
Administer the dose in the drinking water.
Rinse the 1-ml dosing syringe and add the rinse water to the drinker.
Store the syringe clean and dry between the uses.