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POM-V Prescription Required Companion Animal

Eradia 125 mg/ml Oral Suspension for Dogs

Active ingredient: Metronidazole

Form

Liquid

Species

Dogs

Manufacturer

VIRBAC

VMD MA No.

05653/5044

What it's used for

Treatment of infections of the gastrointestinal tract caused by Giardia spp. and Clostridium spp. (i.e. C. perfringens or C. difficile). Treatment of infec...

Full indications, dosage and side effects ↓
View official SPC (PDF)

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Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Eradia 125 mg/ml Oral Suspension for Dogs — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 26 Mar 2026.

Treatment of infections of the gastrointestinal tract caused by Giardia spp. and
Clostridium spp. (i.e. C. perfringens or C. difficile).
Treatment of infections of the urogenital tract, oral cavity, throat and skin caused by
obligate anaerobic bacteria (e.g. Clostridium spp.) susceptible to metronidazole.
Oral use.
The recommended dose is 50 mg metronidazole per kg bodyweight per day (i.e. 0.4
mL per kg bodyweight), preferably given in two equally divided doses (i.e. 25 mg
equivalent to 0.2 mL per kg bodyweight twice daily) for 5-7 days.
To ensure a correct dosage body weight should be determined as accurately as
possible to avoid underdosing and overdosing.
The following table is intended as a guide to dispensing the product at the volume
corresponding to either 25 mg/kg for administration twice daily or 50 mg/kg for
administration once daily.

Revised: April 2024
Divergence from NI MA following AN:03958/2022
Examples of
bodyweight (kg)
Volume to administer twice
daily for 25mg/kg
Volume to administer once
daily for 50mg/kg
10.4mL20.4mL0.8mL30.6mL1.2mL40.8mL1.6mL51.0mL2.0mL102.0mL4.0mL153.0mL6.0mL204.0mL8.0mL255.0mL10.0mL306.0mL12.0mL357.0mL14.0mL408.0mL16.0mL
For doses requiring more than two filled syringes, the dosing should be twice daily in
order to minimize counting and dosing errors.
The oral suspension is delivered through the package described below:
[Snap cap packaging]
A - Shake the bottle vigorously before use.
B - Unscrew the protective overcap.
C - Insert the syringe into the upper white part of the cap (finger-grip) by pushing
firmly, then, while pushing, turn the syringe to the right (clockwise) until the green
smile appears.
D - Turn the bottle upside down and withdraw the prescribed volume of the product,
in the upside down position.
E - Once the correct volume of the product has been drawn into the syringe, unscrew
the syringe from the cap without pushing by turning it to the left (counterclockwise)
until the red smile appears again, then continue to turn in order to unfasten the
syringe.
The system can also be closed by turning the finger-grip manually.
F - Screw the protective overcap back on.
Administer the product by pouring it over a part of the feed or by direct administration
into the animal's mouth. Wear impervious gloves when handling the product and/or
administering the product into the animal's mouth.
When administered over the feed, wait until the animal has completely consumed the
medicated feed, then administer the rest of the feed.

Revised: April 2024
Divergence from NI MA following AN:03958/2022
[Screw cap packaging]
A-Shake vigorously the bottle before use.
B-Push down strongly and turn right the colored part of the cap until it is locked.
C-Open the hindge flap.
D-Plug the syringe on the bottle in upright position.
E-Turn over the bottle and sample the prescribed volume of the product in upside
down position.
F-Once filled, turn over the bottle. Unplug the syringe in upright position.
G-Close the hindge flap.
H-Turn left and pull up the colored part of the cap.
Administer the product by pouring it over a part of the feed or by direct administration
into the animal's mouth. Wear impervious gloves when handling the product and/or
administering the product into the animal's mouth.
When administered over the feed, wait until the animal has completely consumed the
medicated feed, then administer the rest of the feed.

Revised: April 2024
Divergence from NI MA following AN:03958/2022
Do not use in case of hepatic disorders.
Do not use in case of hypersensitivity to the active substance or to any of the
excipients.
The following adverse reactions may occur after administration of metronidazole:
vomiting, hepatotoxicity and neutropenia.
In very rare cases, neurological signs may occur especially after prolonged treatment
with metronidazole.
The frequency of adverse reactions is defined using the following convention:
- very common (more than 1 in 10 animals treated displaying adverse reaction(s))
- common (more than 1 but less than 10 animals in 100 animals treated)
- uncommon (more than 1 but less than 10 animals in 1,000 animals treated)
- rare (more than 1 but less than 10 animals in 10,000 animals treated)
- very rare (less than 1 animal in 10,000 animals treated, including isolated reports).
None.

Revised: April 2024
Divergence from NI MA following AN:03958/2022

Special precautions for use in animals
Due to the likely variability (time, geographical) in the occurrence of metronidazole
resistant bacteria, bacteriological sampling and susceptibility testing are
recommended.
Whenever possible, the product should only be used based on susceptibility testing.
Official, national and regional antimicrobial policies should be taken into account
when the veterinary medicinal product is used.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals
Metronidazole has confirmed mutagenic and genotoxic properties in laboratory
animals as well as in humans. Metronidazole is a confirmed carcinogen in laboratory
animals and thus may have carcinogenic effects in humans as well. However, there
is inadequate evidence in humans for the carcinogenicity of metronidazole.
The product can cause skin sensitisation. In case of known hypersensitivity to
metronidazole or other nitroimidazole derivatives or one of the components of the
product, avoid contact with the veterinary medicinal product.
Avoid contact with the skin or mucous membranes including hand-to-mouth contact.
To avoid such contact wear impervious gloves when handling the product and/or for
direct administration into the animal's mouth.
Do not allow treated dogs to lick persons immediately after intake of the medication.
Wash hands after use.
In case of skin contact, wash thoroughly the affected area.
Metronidazole may cause adverse (neurological) effects.
Avoid accidental ingestion.
Do not drink, eat or smoke when administering the product.
Close the bottle immediately after use to avoid the child gaining access to the
contents. Do not leave a syringe containing solution in the sight or reach of children.
In order to prevent children from getting access to used syringes, keep the syringes
in the original packaging after use.
In case of accidental ingestion, seek-medical advice immediately and show the
package leaflet or the label to physician.
Additional warnings when administering the product into the feed:
Avoid the access of children to the dog’s medicated food. In order to prevent children
from getting access to the dog’s medicated food, pour it over a part of the feed and
wait until the animal has completely consumed the medicated feed, then administer
the rest of the feed. Give the treatment out of the sight and reach of children. Any
uneaten medicated food must be removed immediately and the bowl washed
thoroughly; wear gloves and wash hands when handling the product and cleaning the
contaminated food bowl.

Revised: April 2024
Divergence from NI MA following AN:03958/2022
Metronidazole may have an inhibitory effect on the degradation of other drugs in the
liver, such as phenytoin, cyclosporine and warfarin.
Cimetidine may decrease the hepatic metabolism of metronidazole resulting in
increased serum concentration of metronidazole.
Phenobarbital may increase hepatic metabolism of metronidazole resulting in
decreased serum concentration of metronidazole.
Store below 30° C.
For doses requiring more than two filled syringes, the dosing should be twice daily in
order to minimize counting and dosing errors.
The oral suspension is delivered through the package described below:
[Snap cap packaging]
A - Shake the bottle vigorously before use.
B - Unscrew the protective overcap.
C - Insert the syringe into the upper white part of the cap (finger-grip) by pushing
firmly, then, while pushing, turn the syringe to the right (clockwise) until the green
smile appears.
D - Turn the bottle upside down and withdraw the prescribed volume of the product,
in the upside down position.
E - Once the correct volume of the product has been drawn into the syringe, unscrew
the syringe from the cap without pushing by turning it to the left (counterclockwise)
until the red smile appears again, then continue to turn in order to unfasten the
syringe.
The system can also be closed by turning the finger-grip manually.
F - Screw the protective overcap back on.
Administer the product by pouring it over a part of the feed or by direct administration
into the animal's mouth. Wear impervious gloves when handling the product and/or
administering the product into the animal's mouth.
When administered over the feed, wait until the animal has completely consumed the
medicated feed, then administer the rest of the feed.

Revised: April 2024
Divergence from NI MA following AN:03958/2022
[Screw cap packaging]
A-Shake vigorously the bottle before use.
B-Push down strongly and turn right the colored part of the cap until it is locked.
C-Open the hindge flap.
D-Plug the syringe on the bottle in upright position.
E-Turn over the bottle and sample the prescribed volume of the product in upside
down position.
F-Once filled, turn over the bottle. Unplug the syringe in upright position.
G-Close the hindge flap.
H-Turn left and pull up the colored part of the cap.
Administer the product by pouring it over a part of the feed or by direct administration
into the animal's mouth. Wear impervious gloves when handling the product and/or
administering the product into the animal's mouth.
When administered over the feed, wait until the animal has completely consumed the
medicated feed, then administer the rest of the feed.

Revised: April 2024
Divergence from NI MA following AN:03958/2022
4.10 Overdose (symptoms, emergency procedures, antidotes), if necessary
Adverse events are more likely to occur at doses and treatment durations in excess
of the recommended treatment regimen. If neurological signs occur, treatment should
be discontinued and the patient should be treated symptomatically.
4.11 Withdrawal period(s)
Not applicable.
5.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.

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