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POM-V Prescription Required Companion Animal

Eradia 125 mg/ml Oral Suspension for Dogs

Active ingredient: Metronidazole

Form

Liquid

Species

Dogs

Manufacturer

Virbac

VMD MA No.

05653/3014

What it's used for

Clostridium spp. (i.e. C. perfringens or C. difficile). Treatment of infections of the urogenital tract, oral cavity, throat and skin caused by obligate an...

Full indications, dosage and side effects ↓
View official SPC (PDF)

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Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Eradia 125 mg/ml Oral Suspension for Dogs — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

Clostridium spp. (i.e. C. perfringens or C. difficile).
Treatment of infections of the urogenital tract, oral cavity, throat and skin caused by
obligate anaerobic bacteria (e.g. Clostridium spp.) susceptible to metronidazole.
The recommended dose is 50 mg metronidazole per kg bodyweight per day (i.e. 0.4
mL per kg bodyweight), preferably given in two equally divided doses (i.e. 25 mg

Amended pages: April 2024
equivalent to 0.2 mL per kg bodyweight twice daily) for 5-7 days.
To ensure a correct dosage body weight should be determined as accurately as
possible to avoid underdosing and overdosing.
The following table is intended as a guide to dispensing the veterinary medicinal
product at the volume corresponding to either 25 mg/kg for administration twice daily
or 50 mg/kg for administration once daily.
Examples of bodyweight
(kg)
Volume to administer twice
daily for 25mg/kg
Volume to administer
once daily for 50mg/kg
10.4mL20.4mL0.8mL30.6mL1.2mL40.8mL1.6mL51.0mL2.0mL102.0mL4.0mL153.0mL6.0mL204.0mL8.0mL255.0mL10.0mL306.0mL12.0mL357.0mL14.0mL408.0mL16.0mL
For doses requiring more than two filled syringes, the dosing should be twice daily in
order to minimize counting and dosing errors.
The oral suspension is delivered through the package described below:
[Snap cap packaging]
A - Shake the bottle vigorously before use.
B - Unscrew the protective overcap.
C - Firmly push the valve with the tip of the syringe
D - While pushing, turn the syringe to the right (clockwise) until
the green smile appears.
E - Turn the bottle upside down and withdraw the prescribed volume of the veterinary
medicinal product, in the upside down position.
F - Once the correct volume of the veterinary medicinal product has been drawn into
the syringe, unscrew the syringe from the cap by turning it to the
left (counterclockwise) until the red smile appears again, then continue to turn in
order to unfasten the syringe.
The system can also be closed by turning the finger-grip manually.
G - Screw the protective overcap back on.
Administer the veterinary medicinal product by pouring it over a part of the feed or by
direct administration into the animal's mouth. Wear impervious gloves when handling
the veterinary medicinal product and/or administering the veterinary medicinal
product into the animal's mouth.

Amended pages: April 2024
When administered over the feed, wait until the animal has completely consumed the
medicated feed, then administer the rest of the feed.

Amended pages: April 2024
[Screw cap packaging]
A-Shake vigorously the bottle before use.
B-Push down strongly and turn right the colored part of the cap until it is locked.
C-Open the hindge flap.
D-Plug the syringe on the bottle in upright position.
E-Turn over the bottle and sample the prescribed volume of the veterinary medicinal
product in upside down position.
F-Once filled, turn over the bottle. Unplug the syringe in upright position.
G-Close the hindge flap.
H-Turn left and pull up the colored part of the cap.
Administer the veterinary medicinal product by pouring it over a part of the feed or by
direct administration into the animal's mouth. Wear impervious gloves when handling
the veterinary medicinal product and/or administering the veterinary medicinal
product into the animal's mouth.
When administered over the feed, wait until the animal has completely consumed the
medicated feed, then administer the rest of the feed.
Do not use in cases of hepatic disorders.
Do not use in cases of hypersensitivity to the active substance or to any of the
excipients.
Dogs:
Very rare
(<1 animal / 10,000 animals treated,
including isolated reports):
Neurological signs*
Undetermined frequency (cannot be
estimated from the available data)
Vomiting
Hepatic toxicosis (liver toxicosis)
Neutropenia
*Especially after prolonged treatment with metronidazole.
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder or its local representative or the national
competent authority via the national reporting system. See the package leaflet for
respective contact details.
None.

Amended pages: April 2024

Special precautions for safe use in the target species:
Due to the likely variability (time, geographical) in the occurrence of metronidazole
resistant bacteria, bacteriological sampling and susceptibility testing are
recommended.
Whenever possible, the veterinary medicinal product should only be used based on
susceptibility testing.
Official, national and regional antimicrobial policies should be taken into account
when the veterinary medicinal product is used.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals:
Metronidazole has confirmed mutagenic and genotoxic properties in laboratory
animals as well as in humans. Metronidazole is a confirmed carcinogen in laboratory
animals and thus may have carcinogenic effects in humans as well. However, there
is inadequate evidence in humans for the carcinogenicity of metronidazole.
The veterinary medicinal product can cause skin sensitisation. In case of known
hypersensitivity to metronidazole or other nitroimidazole derivatives or one of the
components of the veterinary medicinal product, avoid contact with the veterinary
medicinal product.
Avoid contact with the skin or mucous membranes including hand-to-mouth contact.
To avoid such contact wear impervious gloves when handling the veterinary
medicinal product and/or for direct administration into the animal's mouth.
Do not allow treated dogs to lick persons immediately after intake of the medication.
Wash hands after use.
In case of skin contact, wash thoroughly the affected area.
Metronidazole may cause adverse (neurological) effects.
Avoid accidental ingestion.
Do not drink, eat or smoke when administering the veterinary medicinal product.
Close the bottle immediately after use to avoid the child gaining access to the
contents. Do not leave a syringe containing suspension in the sight or reach of
children. In order to prevent children from getting access to used syringes, keep the
syringes in the original packaging after use.
In case of accidental ingestion, seek medical advice immediately and show the
package leaflet or the label to the physician.
Additional warnings when administering the veterinary medicinal product into the
feed: Avoid the access of children to the dog’s medicated food. In order to prevent
children from getting access to the dog’s medicated food, pour it over a part of the
feed and wait until the animal has completely consumed the medicated feed, then
administer the rest of the feed. Give the treatment out of the sight and reach of
children. Any uneaten medicated food must be removed immediately and the bowl
washed thoroughly; wear gloves and wash hands when handling the veterinary
medicinal product and cleaning the contaminated food bowl.

Amended pages: April 2024
Special precautions for the protection of the environment:
Not applicable.
Metronidazole may have an inhibitory effect on the degradation of other drugs in the
liver, such as phenytoin, cyclosporine and warfarin.
Cimetidine may decrease the hepatic metabolism of metronidazole resulting in
increased serum concentration of metronidazole.
Phenobarbital may increase hepatic metabolism of metronidazole resulting in
decreased serum concentration of metronidazole.
Store below 30° C.
Not applicable.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.

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