POM-V Prescription Required

Enteroporc COLI AC Lyophilisate and Suspension for Suspension for Injection for Pigs

Active ingredients: Clostridium perfringens, Escherichia coli

Form

Injection

Species

Pigs

Manufacturer

Ceva Animal Health Ltd

VMD MA No.

15052/5002

What it's used for

For the passive immunisation of progeny by active immunisation of pregnant sows and gilts to reduce: -Escherichia coli strains expressing the fimbrial adhe...

Full indications, dosage and side effects ↓

View official SPC (PDF)

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Clinical information

Enteroporc COLI AC Lyophilisate and Suspension for Suspension for Injection for Pigs — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 26 Mar 2026.

For the passive immunisation of progeny by active immunisation of pregnant sows and
gilts to reduce:
-Escherichia coli strains
expressing the fimbrial adhesins F4ab, F4ac, F5 and F6
-Clostridium
perfringens type A expressing alpha and beta2 toxins
-
caused by type C expressing beta1 toxin
Onset of immunity (after uptake of colostrum):
E. coli F4ab, F4ac, F5, F6: within 12 hours after birth
C. perfringens type A and C: First day of life
Duration of immunity (after uptake of colostrum):
E. coli F4ab, F4ac, F5, F6: first days of life
C. perfringens type A: 14 days of life
C. perfringens types C: 21 days of life

Intramuscular use.
Inject one dose (2 ml) of vaccine into the neck muscles in the area behind the ear of
each pig.
Vaccination scheme:
Primary vaccination:
First vaccination: one dose 5 weeks before the expected date of farrowing.
Second vaccination: one dose 2 weeks before the expected date of farrowing.
Revaccination (before each subsequent farrowing): one dose 2 weeks before the
expected date of farrowing.
Preparation of the vaccine:
1. To reconstitute the vaccine, use an appropriately sized sterile syringe to withdraw
approximately 5 ml of the suspension and transfer it into the vial containing the
lyophilisate.
2. Shake gently until the lyophilisate is completely dispersed in the suspension.
3. Then withdraw all the contents of the lyophilisate vial into the same syringe and
transfer them back into the suspension vial.
4. Shake well until thoroughly mixed.
5. Withdraw approximately 5 ml of the reconstituted vaccine suspension and transfer it
into lyophilisate vial. Shake the vial. Then withdraw the contents and transfer them back
into the vaccine suspension vial.
The vaccine is ready to use.

Revised: March 2025
AN: 01848/2024
The reconstituted vaccine is a yellowish brown to reddish brown suspension.

None.

A transient increase in body temperature (mean 0.5 °C, in individual pigs up to 2 °C)
occurred very commonly on the day of vaccination which returned to normal within 24
hours.
A transient swelling and redness at the injection site (mean 2.8 cm, in individual pigs up
to 8 cm) was very commonly observed which disappeared without treatment within 7
days.
A slightly depressed behaviour was commonly observed on the days of vaccination.

Revised: March 2025
AN: 01848/2024
The frequency of adverse reactions is defined using the following convention:
- very common (more than 1 in 10 animals treated displaying adverse reaction(s))
- common (more than 1 but less than 10 animals in 100 animals treated)
- uncommon (more than 1 but less than 10 animals in 1,000 animals treated)
- rare (more than 1 but less than 10 animals in 10,000 animals treated)
- very rare (less than 1 animal in 10,000 animals treated, including isolated reports).

Vaccinate healthy animals only.

Special precautions for use in animals
Not applicable.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals
None.

No information is available on the safety and efficacy of this vaccine when used with
any other veterinary medicinal product. A decision to use this vaccine before or after
any other veterinary medicinal product therefore needs to be made on a case by case
basis.

Store and transport refrigerated (2 C – 8 C).
Protect from light.
Do not freeze.

into lyophilisate vial. Shake the vial. Then withdraw the contents and transfer them back
into the vaccine suspension vial.
The vaccine is ready to use.

Revised: March 2025
AN: 01848/2024
The reconstituted vaccine is a yellowish brown to reddish brown suspension.
4.10 Overdose (symptoms, emergency procedures, antidotes), if necessary
Not applicable.
4.11 Withdrawal period(s)
Zero days.
5. IMMUNOLOGICAL PROPERTIES
Pharmacotherapeutic group: Immunologicals for Suidae, inactivated bacterial vaccines.
ATC vet code: QI09AB08.
The active immunisation of pregnant sows and gilts induces the formation of antibodies
against the alpha, beta1 and beta2 toxins of C. perfringens types A and C and against
E. coli fimbrial adhesins F4ab, F4ac, F5 and F

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.