Enroxil 100 mg/ml Solution for Injection for Cattle and Pigs
Active ingredient: Enrofloxacin
Form
Injection
Species
Manufacturer
KRKA, d.d., Novo mesto
VMD MA No.
01656/5067
What it's used for
Cattle: Treatment of infections of the respiratory tract caused by enrofloxacin susceptible strains of Pasteurella multocida, Mannheimia haemolytica and My...
Full indications, dosage and side effects ↓The prescription itself has a price. See what practices near you charge for a consultation and the written prescription fee.
Paying less for Enrofloxacin
-
1
Ask your vet for a written prescription
They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.
-
2
Fill it at a registered online retailer
The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.
Done — we'll email you when prices land.
Prescription required
Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.
Enroxil 100 mg/ml Solution for Injection for Cattle and Pigs — SPC Details
Source: VMD Summary of Product Characteristics (SPC). Last updated 26 Mar 2026.
Treatment of infections of the respiratory tract caused by enrofloxacin susceptible strains
of Pasteurella multocida, Mannheimia haemolytica and Mycoplasma spp.
Treatment of acute severe mastitis caused by enrofloxacin susceptible strains of
Escherichia coli.
Treatment of infections of the alimentary tract caused by enrofloxacin susceptible strains
of Escherichia coli.
Treatment of septicaemia caused by enrofloxacin susceptible strains of Escherichia coli.
Treatment of acute mycoplasma-associated arthritis due to enrofloxacin susceptible
strains of Mycoplasma bovis in cattle less than 2 years old.
Pigs:
Treatment of infections of the respiratory tract caused by enrofloxacin susceptible strains
of Pasteurella multocida, Mycoplasma spp. and Actinobacillus pleuropneumoniae.
Treatment of infections of the urinary tract caused by enrofloxacin susceptible strains of
Escherichia coli.
Revised: May 2024
AN: 00448/2023Page 2 of 8
Treatment of post-partum dysgalactiae syndrome, PDS (MMA syndrome) caused by
enrofloxacin susceptible strains of Escherichia coli and Klebsiella spp.
Treatment of infections of the alimentary tract caused by enrofloxacin susceptible strains
of Escherichia coli.
Treatment of septicaemia caused by enrofloxacin susceptible strains of Escherichia coli.
Repeated injections should be made at different injection sites.
To ensure a correct dosage, body weight should be determined as accurately as possible.
Cattle:
5 mg of enrofloxacin/kg bw, corresponding to 1 ml/20 kg bw, once daily for 3-5 days.
Acute mycoplasma-associated arthritis due to enrofloxacin susceptible strains of
Mycoplasma bovis in cattle less than 2 years old: 5 mg of enrofloxacin/kg bw,
corresponding to 1 ml/20 kg bw, once daily for 5 days.
The veterinary medicinal product can be administered by slow intravenous or
subcutaneous administration.
Acute mastitis caused by
ml/20 kg bw, by slow intravenous injection once daily for two consecutive days.
The second dose may be administered by the subcutaneous route. In this case, the
withdrawal period following subcutaneous injection applies.
Cattle: Not more than 10 ml should be administered at one subcutaneous injection site.
Calves: Not more than 5 ml should be administered at one subcutaneous injection site.
Pigs:
2.5 mg of enrofloxacin/kg bw, corresponding to 0.5 ml/20 kg bw, once daily by
intramuscular injection for 3 days.
Alimentary tract infection or septicaemia caused by Escherichia coli: 5 mg of
enrofloxacin/kg bw, corresponding to 1 ml/20 kg bw, once daily by intramuscular injection
for 3 days.
In pigs, the injection should be made in the neck at the ear base.
Not more than 3 ml should be administered at one intramuscular injection site.
If there is no clinical improvement within two to three days, further susceptibility testing and
possibly a change in antimicrobial therapy should be considered.
Do not exceed the recommended dose.
Revised: May 2024
AN: 00448/2023Page 5 of 8
Normal sterile precautions should be taken.
Do not use in cases of resistance against quinolones.
Do not use in cases of disturbances in growth of cartilages and/or during injury of
locomotory system particularly on functionally loaded joints or due to body weight loaded
joints.
Do not use in growing horses because of possible deleterious damage on articular
cartilage.
Do not use in cases of hypersensitivity to the active substance or to any of the excipients.
Very rare
(<1 animal / 10,000 animals
treated, including isolated
reports):
Digestive tract disorders (e.g. diarrhoea)
Circulatory shock
Injection site reaction
Generally mild and transient.
Following intravenous administration.
Pigs:
Very rare
(<1 animal / 10,000 animals
treated, including isolated
reports):
Digestive tract disorders (e.g., diarrhoea)
Undetermined frequency
(cannot be estimated from the
available data):
Injection site inflammation
1
Generally mild and transient.
May persist up to 28 days.
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder or its local representative or the national
competent authority via the national reporting system. See also section 16 of the package
leaflet for contact details.
Special precautions for use in animals
Official and local antimicrobial policies should be taken into account when the veterinary
medicinal product is used.
Fluoroquinolones should be reserved for the treatment of clinical conditions which have
responded poorly, or are expected to respond poorly, to other classes of antimicrobials.
Whenever possible fluoroquinolones should only be used based on susceptibility testing.
Use of the veterinary medicinal product including use deviating from the instructions given
in the SPC may increase the prevalence of bacteria resistant to enrofloxacin and may
decrease the effectiveness of treatment with all fluoroquinolones due to the potential for
cross-resistance.
Treatment should not be repeated if an allergic reaction occurs.
Enrofloxacin is partially excreted through the kidney. In case of the kidney’s functional
failure slower excretion should be taken into account.
Degenerative changes of articular cartilage were observed in calves treated orally with 30
mg enrofloxacin/kg bw during 14 days.
The use of enrofloxacin in growing lambs at the recommended dose for 15 days caused
histological changes in the articular cartilage, not associated with clinical signs.
Do not re-inject into the same injection site.
The cap may be safely punctured up to 40 times. When treating groups of animals, use a
draw-off needle.
Only the 50 ml vial should be used to treat small piglets.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals
People with known hypersensitivity to fluoroquinolones should avoid any contact with the
veterinary medicinal product.
Avoid skin and eye contact. Wash any splashes from skin or eyes immediately with water.
Revised: May 2024
AN: 00448/2023Page 3 of 8
Wash hands after use. Do not eat, drink or smoke whilst handling the veterinary medicinal
product.
Care should be taken to avoid accidental self-injection. In case of accidental self-injection,
seek medical advice immediately and show the package leaflet or the label to the
physician.
Special precautions for the protection of the environment:
Not applicable.
Other precautions
In countries where feeding of fallen stock to scavenger bird populations is permitted as a
conservation measure (see Commission Decision 2003/322/EC), the possible risk to
hatching success should be considered before feeding carcasses of livestock recently
treated with this veterinary medicinal product.
antagonistically to quinolones (e. g. macrolides, tetracyclines or phenicols).
Do not use concurrently with theophylline as the elimination of theophylline may be
delayed.
Keep the bottle in the outer carton.
Calves: Not more than 5 ml should be administered at one subcutaneous injection site.
Pigs:
2.5 mg of enrofloxacin/kg bw, corresponding to 0.5 ml/20 kg bw, once daily by
intramuscular injection for 3 days.
Alimentary tract infection or septicaemia caused by Escherichia coli: 5 mg of
enrofloxacin/kg bw, corresponding to 1 ml/20 kg bw, once daily by intramuscular injection
for 3 days.
In pigs, the injection should be made in the neck at the ear base.
Not more than 3 ml should be administered at one intramuscular injection site.
If there is no clinical improvement within two to three days, further susceptibility testing and
possibly a change in antimicrobial therapy should be considered.
Do not exceed the recommended dose.
Revised: May 2024
AN: 00448/2023Page 5 of 8
Normal sterile precautions should be taken.
4.10 Overdose (symptoms, emergency procedures, antidotes), if necessary
In cases of accidental overdoses digestive tract disorders (e.g. vomiting, diarrhoea) and
neurological disorders may occur.
In pigs, no adverse effects were reported after the administration of 5 times the
recommended dose.
In cattle, overdose has not been documented.
In accidental overdose there is no antidote and treatment should be symptomatic.
4.11 Withdrawal period(s)
Cattle
Intravenous use:
Meat and offal: 5 days.
Milk: 3 days.
Subcutaneous use:
Meat and offal: 12 days.
Milk: 4 days.
Pigs:
Meat and offal: 13 days.
5.
This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.
Medication costs adding up?
Pet insurance can cover prescription medications. Find the right policy for your pet.
Related Conditions
Other Products Containing Enrofloxacin
These products share the same active ingredient and may be suitable alternatives. Always consult your vet.
Baytril 100 mg/ml Solution for Injection
POM-VElanco GmbH
Baytril 100 mg/ml Solution for Injection
POM-VElanco GmbH
Baytril 100 mg/ml Solution for use in Drinking Water for Chickens, Turkeys and Rabbits
POM-VElanco GmbH
Baytril 100 mg/ml Solution for use in Drinking Water for Chickens, Turkeys and Rabbits
POM-VElanco GmbH
Baytril 25 mg/ml Oral Solution
POM-VElanco GmbH
Baytril 25 mg/ml Oral Solution
POM-VElanco GmbH
Alternative options to consider
Retailers we earn a commission from. It costs you nothing and never changes what we show.
The Pharm Pet Co. — Pet Pharmacy
UK online pet pharmacy. Flea, worm, prescription medications, supplements and pet food. Save vs vet prices.
Pet Care at Pharmacy2U
The UK's largest online pharmacy. Pet wormers, flea treatments, dental and joint care. Free delivery on orders over £30.
KatKin Fresh Cat Food
The UK's top-rated cat food. 100% fresh, human-quality meat, gently cooked and delivered frozen. Vet-formulated for every life stage.
We may earn a small commission if you purchase through these links, at no extra cost to you.
Related Medications
Actionis 50 mg/ml, Suspension for Injection for Pigs and Cattle
POM-VCeftiofur
Actionis 50 mg/ml, Suspension for Injection for Pigs and Cattle
POM-VCeftiofur
Adaxio Shampoo for Dogs
POM-VChlorhexidine Gluconate + Miconazole Nitrate
Adaxio Shampoo for Dogs
POM-VChlorhexidine Gluconate + Miconazole Nitrate
Advocin 180, 180 mg/ml, Solution for Injection for Cattle
POM-VDanofloxacin
Aivlosin 42.5 mg/g Oral Powder for Pigs
POM-VTylvalosin
Find cheaper vets near you
Compare vet consultation prices in your area. Save on procedures and get a prescription to buy medications online.