Baytril 100 mg/ml Solution for Injection
Active ingredient: Enrofloxacin
Form
Injection
Species
Manufacturer
Elanco GmbH
VMD MA No.
52127/3046
What it's used for
Cattle Treatment of infections of the respiratory tract caused by enrofloxacin susceptible strains of Mycoplasma spp. Treatment of acute severe mastitis ca...
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Baytril 100 mg/ml Solution for Injection — SPC Details
Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.
Treatment of infections of the respiratory tract caused by enrofloxacin
susceptible strains of
Mycoplasma spp.
Treatment of acute severe mastitis caused by enrofloxacin susceptible strains
of Escherichia coli.
Treatment of infections of the alimentary tract caused by enrofloxacin
susceptible strains of Escherichia coli.
Treatment of septicaemia caused by enrofloxacin susceptible strains of
Escherichia coli
Treatment of acute mycoplasma-associated arthritis due to enrofloxacin
susceptible strains of Mycoplasma bovis in cattle less than 2 years old.
Sheep
Treatment of infections of the alimentary tract caused by enrofloxacin
susceptible strains of Escherichia coli.
Treatment of septicaemia caused by enrofloxacin susceptible strains of
Escherichia coli
Revised: September 2025
AN: 01467/2025
Treatment
of
mastitis
caused
by
enrofloxacin
susceptible
strains
of
Staphylococcus aureus
Goats
Treatment of infections of the respiratory tract caused by enrofloxacin
susceptible strains of Pasteurella multocida and Mannheimia haemolytica.
Treatment of infections of the alimentary tract caused by enrofloxacin
susceptible strains of Escherichia coli.
Treatment of septicaemia caused by enrofloxacin susceptible strains of
Escherichia coli
Treatment
of
mastitis
caused
by
enrofloxacin
susceptible
strains
of
Staphylococcus aureus
Pigs
Treatment of infections of the respiratory tract caused by enrofloxacin
susceptible strains of
Actinobacillus pleuropneumoniae.
Treatment of infections of the urinary tract caused by enrofloxacin susceptible
strains of Escherichia coli.
Treatment of post-partum dysgalactiae syndrome, PDS (MMA syndrome)
caused by enrofloxacin susceptible strains of
spp.
Treatment of infections of the alimentary tract caused by enrofloxacin
susceptible strains of Escherichia coli.
Treatment of septicaemia caused by enrofloxacin susceptible strains of
Escherichia coli
Repeated injections should be made at different injection sites.
To ensure a correct dosage, body weight (bw) should be determined as accurately
as possible to avoid underdosing.
Revised: September 2025
AN: 01467/2025
Cattle
5 mg of enrofloxacin/kg bw, corresponding to 1 ml/20 kg bw, once daily for 3–5
days.
Acute mycoplasma-associated arthritis due to enrofloxacin susceptible strains
of
bw, corresponding to 1 ml/20 kg bw, once daily for 5 days.
The product can be administered by slow intravenous or subcutaneous
administration.
Acute mastitis caused by : 5 mg enrofloxacin/kg bw,
corresponding to 1 ml/20 kg bw, by slow intravenous injection once daily for
two consecutive days.
The second dose may be administered by the subcutaneous route. In this
case, the withdrawal period following subcutaneous injection applies.
Not more than 10 ml should be administered at one subcutaneous injection
site.
Sheep and goats
5 mg of enrofloxacin/kg bw, corresponding to 1 ml/20 kg bw, once daily by
subcutaneous injection for 3 days.
Not more than 6 ml should be administered at one subcutaneous injection
site.
Pigs
2.5 mg of enrofloxacin/kg bw, corresponding to 0.5 ml/20 kg bw, once daily
by intramuscular injection for 3 days.
Alimentary tract infection, or septicaemia caused by : 5 mg of
enrofloxacin/kg bw, corresponding to 1 ml/20 kg bw, once daily by
intramuscular injection for 3 days.
In pigs, the injection should be made in the neck at the ear base.
Not more than 3 ml should be administered at one intramuscular injection site.
fluoroquinolones or to any of the excipients.
Do not use in growing horses because of possible deleterious damage on
articular cartilage.
signs are generally mild and transient.
In very rare cases intravenous treatment of cattle can cause shock reactions,
presumably as a result of circulatory impairment.
In very rare cases, neurological signs (seizures, tremors, ataxia, excitation) and
anaphylactic reactions can also occur.
Local reactions at injection site
In pigs, after intramuscular administration of the product, inflammatory
reactions may occur. They may persist up to 28 days after the injection.
Revised: September 2025
AN: 01467/2025
The frequency of adverse reactions is defined using the following
convention:
- very common (more than 1 in 10 animals displaying adverse reactions
during the course of one treatment)
- common (more than 1 but less than 10 animals in 100 animals)
- uncommon (more than 1 but less than 10 animals in 1,000 animals)
- rare (more than 1 but less than 10 animals in 10,000 animals)
- very rare (less than 1 animal in 10,000 animals, including isolated
reports).
i) Special precautions for use in animals
Official and local antimicrobial policies should be taken into account when the
product is used.
Fluoroquinolones should be reserved for the treatment of clinical conditions
which have responded poorly, or are expected to respond poorly, to other
classes of antimicrobials.
Revised: September 2025
AN: 01467/2025
Whenever possible fluoroquinolones should only be used based on
susceptibility testing.
Use of the product including use deviating from the instructions given in the
SPC may increase the prevalence of bacteria resistant to enrofloxacin and may
decrease the effectiveness of treatment with all fluoroquinolones due to the
potential for cross-resistance.
Degenerative changes of articular cartilage were observed in calves treated
orally with 30 mg enrofloxacin/kg body weight during 14 days.
The use of enrofloxacin in growing lambs at the recommended dose for 15
days caused histological changes in the articular cartilage, not associated to
clinical signs.
ii) Special precautions to be taken by the person administering the
veterinary medicinal product to animals
Enrofloxacin may cause hypersensitivity (allergic reactions). People with
known hypersensitivity to fluoroquinolones (e.g., enrofloxacin or ciprofloxacin)
should avoid any contact with the product.
The product may be irritating to skin and eyes. In case of contact with skin or
eyes, wash the affected area with clear running water.
Wash hands after use. Do not eat, drink or smoke whilst handling the product.
Care should be taken to avoid accidental self-injection. If accidental self-injection
occurs seek medical advice immediately.
iii) Other precautions
In countries where feeding of fallen stock to scavenger bird populations is
permitted as a conservation measure (see Commission Decision
2003/322/EC), the possible risk to hatching success should be considered
before feeding carcasses of livestock recently treated with this product.
Do not use enrofloxacin concomitantly with antimicrobial substances acting
antagonistically to quinolones (e.g. macrolides, tetracyclines or phenicols).
Do not use concurrently with theophylline as the elimination of theophylline
may be delayed.
conditions.
site.
Sheep and goats
5 mg of enrofloxacin/kg bw, corresponding to 1 ml/20 kg bw, once daily by
subcutaneous injection for 3 days.
Not more than 6 ml should be administered at one subcutaneous injection
site.
Pigs
2.5 mg of enrofloxacin/kg bw, corresponding to 0.5 ml/20 kg bw, once daily
by intramuscular injection for 3 days.
Alimentary tract infection, or septicaemia caused by : 5 mg of
enrofloxacin/kg bw, corresponding to 1 ml/20 kg bw, once daily by
intramuscular injection for 3 days.
In pigs, the injection should be made in the neck at the ear base.
Not more than 3 ml should be administered at one intramuscular injection site.
4.10 Overdose (symptoms, emergency procedures, antidotes), if
necessary
In cases of accidental overdoses digestive tract disorders (e.g. vomiting,
diarrhoea) and neurological disorders may occur.
In pigs, no adverse effects were reported after the administration of 5 times the
recommended dose.
In cattle, sheep and goat, overdose has not been documented.
Revised: September 2020
AN: 00778/2020
In accidental overdose there is no antidote and treatment should be
symptomatic.
4.11 Withdrawal periods
Cattle:
Following intravenous injection:
Meat and offal: 5 days. Milk: 3
days.
Following subcutaneous injection:
Meat and offal: 12 days. Milk:
4 days.
Sheep:
Meat and offal: 4 days. Milk: 3
days.
Goats:
Meat and offal: 6 days. Milk: 4
days.
Pigs:
Meat and offal: 13 days.
5.
This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.
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