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POM-V Prescription Required

Enroxil 100 mg/ml Oral Solution for Chickens and Turkeys

Active ingredient: Enrofloxacin

Form

Liquid

Species

Chickens Turkeys

Manufacturer

KRKA, d.d., Novo mesto

VMD MA No.

01656/4021

What it's used for

Treatment of infections caused by the following bacteria susceptible to enrofloxacin: Chickens Mycoplasma gallisepticum, Mycoplasma synoviae, Avibacterium...

Full indications, dosage and side effects ↓
View official SPC (PDF)

The prescription itself has a price. See what practices near you charge for a consultation and the written prescription fee.

Paying less for Enrofloxacin

  1. 1

    Ask your vet for a written prescription

    They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.

  2. 2

    Fill it at a registered online retailer

    The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Enroxil 100 mg/ml Oral Solution for Chickens and Turkeys — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 26 Mar 2026.

Treatment of infections caused by the following bacteria susceptible to enrofloxacin:
Chickens
Mycoplasma gallisepticum,
Mycoplasma synoviae,
Avibacterium paragallinarum,
Pasteurella multocida.
Turkey
Mycoplasma gallisepticum,
Mycoplasma synoviae,
Pasteurella multocida.
Dosage:
Chickens and turkeys
10 mg enrofloxacin/kg bodyweight per day for 3–5 consecutive days.
Treatment for 3–5 consecutive days; for 5 consecutive days in mixed infections and
chronic progressive forms. If no clinical improvement is achieved within 2–3 days,
alternative antimicrobial therapy should be considered based on susceptibility testing.
The uptake of medicated water depends on the clinical condition of the animals. In
order to obtain the correct dosage the concentration of Enroxil should be adjusted
accordingly. Taking into consideration that 10 mg enrofloxacin per kg body weight
corresponds to 0.1 ml of Enroxil per kg body weight; the following calculation should
be made to provide the required amount of Enroxil per litre of drinking water:
ml Enroxil per average bodyweight (kg) number of
kg bodyweight X of the animals to be X animals
daily treated
-------------------------------------------------------------------------------------- = ml Enroxil per litre
Total water consumption (l) of the flock at the previous day drinking water
Care should be taken that the intended dose is completely ingested.
The product may be put directly into the header tank or introduced via a water
proportioner pump. For the preparation of the medicated water for small groups of
animals the measuring cup included with the packaging should be used. During
preparation of medicated water, the product should be admixed into water and not
the other way round.
Only sufficient medicated drinking water should be prepared to cover the daily
requirements. Medicated water should be prepared every day, immediately prior to
provision. Medication of the water supply should be continuous during the treatment

Revised: March 2026
AN: 03567/2025Page 4 of 6
period and no other source of water should be available.
Medicated drinking water should be replaced every 24 hours.
Do not use for prophylaxis.
Do not use when resistance / cross-resistance to (fluoro)quinolones is known to
occur in the flock intended for treatment.
Infections caused by Streptococcus spp., because of only marginal susceptibility to
enrofloxacin.
Do not use in other animals.
.

Revised: March 2026
AN: 03567/2025Page 2 of 6
Do not use in case of hypersensitivity to the active substance, or to any of the
excipients.
Locomotion disturbances as a result of damage of joint cartilage could not be
excluded in case that fluoroquinolones are used during the growing period,
particularly at higher temperatures, when consumption of medicated water is
drastically increased for longer period.

Revised: March 2026
AN: 03567/2025Page 3 of 6
Treatment of Mycoplasma

Special precautions for use in animals
Official and local antimicrobial policies should be taken into account when the
product is used.
Fluoroquinolones should be reserved for the treatment of clinical conditions which
have responded poorly, or are expected to respond poorly, to other classes of
antimicrobials.
Whenever possible, fluoroquinolones should only be used based on susceptibility
testing.
Use of the product deviating from the instructions given in the SPC may increase the
prevalence of bacteria resistant to the fluoroquinolones and may decrease the
effectiveness of treatment with other quinolones due to the potential for cross
resistance.
Since enrofloxacin was first authorised for use in poultry, there has been widespread
reduction in susceptibility of
organisms. Resistance has also been reported in Mycoplasma synoviae in the EU.
As enrofloxacin will be partly excreted via kidneys, elimination will be delayed in
cases with kidney disorders.
Special precautions to be taken by the person administering the veterinary
medicinal product to animals
Personal protective equipment consisting of impervious gloves should be worn when
handling the veterinary medicinal product.
Wash any splashes from skin or eyes immediately with water.
Wash hands and exposed skin after use.
Do not eat, drink or smoke while using the product.
Other precautions:
After the end of treatment, the watering system should be cleaned appropriately to
prevent the intake of remaining subtherapeutic doses of the drug, which may lead to
resistance.
When combined with tetracyclines and macrolide antibiotics, enrofloxacin may
produce an antagonistic effect.
Resorption of enrofloxacin may be reduced, when it is combined with substances
containing magnesium or aluminium.
The serum level of theophylline may increase when it is combined with enrofloxacin.
Do not combine enrofloxacin with non steroidal antiphlogistics.
Increased influx of the air (admixing CO2 from the air) into medicated drinking water
may result in precipitation of enrofloxacin.
Precipitation of the salt of enrofloxacin and alkalis may occur at higher concentration
of calcium and magnesium in the water system during intermediate dilution in the
dosage devices.
Store in the original package in order to protect from light.
Chickens: Meat and offal: 7 days
Turkeys: Meat and offal: 13 days
Not authorised for use in laying birds producing eggs for human consumption.
Do not administer to layer replacement birds within 14 days of coming into lay.
5.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.

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