POM-V
Prescription Required
Companion Animal
Enrotron 50 mg/ml Solution for Injection for Cattle, Sheep, Goats, Pigs, Dogs and Cats
Active ingredient: Enrofloxacin
Form
Injection
Species
Cats
Cattle
Dogs
Goats
Pigs
Sheep
Manufacturer
aniMedica GmbH
VMD MA No.
24745/4030
What it's used for
Treatment of infections of the alimentary tract caused by enrofloxacin susceptible strains of Escherichia coli. Treatment of septicaemia caused by enroflox...
Full indications, dosage and side effects ↓The prescription itself has a price. See what practices near you charge for a consultation and the written prescription fee.
Paying less for Enrofloxacin
-
1
Ask your vet for a written prescription
They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.
-
2
Fill it at a registered online retailer
The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.
Done — we'll email you when prices land.
Prescription required
Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.
Clinical information
Enrotron 50 mg/ml Solution for Injection for Cattle, Sheep, Goats, Pigs, Dogs and Cats — SPC Details
Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.
Treatment of infections of the alimentary tract caused by enrofloxacin susceptible
strains of Escherichia coli.
Treatment of septicaemia caused by enrofloxacin susceptible strains of Escherichia
coli
Treatment of acute mycoplasma-associated arthritis due to enrofloxacin susceptible
strains of
Mycoplasma bovis.
Sheep
Treatment of infections of the alimentary tract caused by enrofloxacin susceptible
strains of
AN: 02463/2024 & 02464/2024 Page 2 of 8
Treatment of septicaemia caused by enrofloxacin susceptible strains of
coli.
Treatment of mastitis caused by enrofloxacin susceptible strains of
aureus
Goats
Treatment of infections of the respiratory tract caused by enrofloxacin susceptible
strains of .
Treatment of infections of the alimentary tract caused by enrofloxacin susceptible
strains of
Treatment of septicaemia caused by enrofloxacin susceptible strains of
coli
Treatment of mastitis caused by enrofloxacin susceptible strains of
aureus
Pigs
Treatment of infections of the respiratory tract caused by enrofloxacin susceptible
strains of Pasteurella multocidaMycoplasma spp. and Actinobacillus
pleuropneumoniae.
Treatment of infections of the alimentary tract caused by enrofloxacin susceptible
strains of Escherichia coli.
Treatment of septicaemia caused by enrofloxacin susceptible strains of Escherichia
coli
Dogs
Treatment of infections of the alimentary, respiratory and urogenital tracts (including
prostatitis, adjunctive antibiotic therapy for pyometra), skin and wound infections, otitis
(externa/media) caused by enrofloxacin susceptible strains of Staphylococcus spp.,
Escherichia coli, Pasteurella spp., Klebsiella spp., Bordetella spp., Pseudomonas spp.
and Proteus spp.
Cats
Treatment of infections of the alimentary, respiratory and urogenital tracts (as
adjunctive antibiotic therapy for pyometra), skin and wound infections, caused by
enrofloxacin susceptible strains of, e.g.: Staphylococcus spp., Escherichia coli,
Pasteurella spp., Klebsiella spp., Bordetella spp.spp. and Proteus
strains of Escherichia coli.
Treatment of septicaemia caused by enrofloxacin susceptible strains of Escherichia
coli
Treatment of acute mycoplasma-associated arthritis due to enrofloxacin susceptible
strains of
Mycoplasma bovis.
Sheep
Treatment of infections of the alimentary tract caused by enrofloxacin susceptible
strains of
AN: 02463/2024 & 02464/2024 Page 2 of 8
Treatment of septicaemia caused by enrofloxacin susceptible strains of
coli.
Treatment of mastitis caused by enrofloxacin susceptible strains of
aureus
Goats
Treatment of infections of the respiratory tract caused by enrofloxacin susceptible
strains of .
Treatment of infections of the alimentary tract caused by enrofloxacin susceptible
strains of
Treatment of septicaemia caused by enrofloxacin susceptible strains of
coli
Treatment of mastitis caused by enrofloxacin susceptible strains of
aureus
Pigs
Treatment of infections of the respiratory tract caused by enrofloxacin susceptible
strains of Pasteurella multocidaMycoplasma spp. and Actinobacillus
pleuropneumoniae.
Treatment of infections of the alimentary tract caused by enrofloxacin susceptible
strains of Escherichia coli.
Treatment of septicaemia caused by enrofloxacin susceptible strains of Escherichia
coli
Dogs
Treatment of infections of the alimentary, respiratory and urogenital tracts (including
prostatitis, adjunctive antibiotic therapy for pyometra), skin and wound infections, otitis
(externa/media) caused by enrofloxacin susceptible strains of Staphylococcus spp.,
Escherichia coli, Pasteurella spp., Klebsiella spp., Bordetella spp., Pseudomonas spp.
and Proteus spp.
Cats
Treatment of infections of the alimentary, respiratory and urogenital tracts (as
adjunctive antibiotic therapy for pyometra), skin and wound infections, caused by
enrofloxacin susceptible strains of, e.g.: Staphylococcus spp., Escherichia coli,
Pasteurella spp., Klebsiella spp., Bordetella spp.spp. and Proteus
Repeated injections should be made at different injection sites.
AN: 02463/2024 & 02464/2024 Page 5 of 8
To ensure a correct dosage, body weight (bw) should be determined as accurately as
possible.
Cattle (calves):
5 mg of enrofloxacin/kg bw, corresponding to 1 ml/10 kg bw, once daily for 3-5 days.
Acute mycoplasma-associated arthritis due to enrofloxacin susceptible strains of
Mycoplasma bovis: 5 mg of enrofloxacin/kg bw, corresponding to 1 ml/10 kg bw, once
daily for 5 days.
The veterinary medicinal product can be administered by slow intravenous or
subcutaneous administration.
Not more than 10 ml should be administered at one subcutaneous injection site.
Sheep and goats:
5 mg of enrofloxacin/kg bw, corresponding to 1 ml/10 kg bw, once daily by
subcutaneous injection for 3 days. Not more than 6 ml should be administered at one
subcutaneous injection site.
Pigs:
2.5 mg of enrofloxacin/kg bw, corresponding to 0.5 ml/10 kg bw, once daily by
intramuscular injection for 3 days.
Alimentary tract infection or septicaemia caused by Escherichia coli: 5 mg of
enrofloxacin/kg bw, corresponding to 1 ml/10 kg bw, once daily by intramuscular
injection for 3 days.
In pigs, the injection should be made in the neck at the ear base.
Not more than 3 ml should be administered at one intramuscular injection site.
Dogs and cats:
5 mg of enrofloxacin/kg bw, corresponding to 1 ml/10 kg bw, daily by subcutaneous
injection for up to 5 days.
Treatment may be initiated with injectable veterinary medicinal product and maintained
with enrofloxacin tablets. Duration of treatment should be based on the duration of
treatment approved for the appropriate indication in the SPC of the tablet veterinary
medicinal product.
AN: 02463/2024 & 02464/2024 Page 5 of 8
To ensure a correct dosage, body weight (bw) should be determined as accurately as
possible.
Cattle (calves):
5 mg of enrofloxacin/kg bw, corresponding to 1 ml/10 kg bw, once daily for 3-5 days.
Acute mycoplasma-associated arthritis due to enrofloxacin susceptible strains of
Mycoplasma bovis: 5 mg of enrofloxacin/kg bw, corresponding to 1 ml/10 kg bw, once
daily for 5 days.
The veterinary medicinal product can be administered by slow intravenous or
subcutaneous administration.
Not more than 10 ml should be administered at one subcutaneous injection site.
Sheep and goats:
5 mg of enrofloxacin/kg bw, corresponding to 1 ml/10 kg bw, once daily by
subcutaneous injection for 3 days. Not more than 6 ml should be administered at one
subcutaneous injection site.
Pigs:
2.5 mg of enrofloxacin/kg bw, corresponding to 0.5 ml/10 kg bw, once daily by
intramuscular injection for 3 days.
Alimentary tract infection or septicaemia caused by Escherichia coli: 5 mg of
enrofloxacin/kg bw, corresponding to 1 ml/10 kg bw, once daily by intramuscular
injection for 3 days.
In pigs, the injection should be made in the neck at the ear base.
Not more than 3 ml should be administered at one intramuscular injection site.
Dogs and cats:
5 mg of enrofloxacin/kg bw, corresponding to 1 ml/10 kg bw, daily by subcutaneous
injection for up to 5 days.
Treatment may be initiated with injectable veterinary medicinal product and maintained
with enrofloxacin tablets. Duration of treatment should be based on the duration of
treatment approved for the appropriate indication in the SPC of the tablet veterinary
medicinal product.
Do not treat dogs under 1 year of age with the veterinary medicinal product as damage
to the articular cartilage may occur during the period of rapid growth, specifically in
large breeds of dogs. As a precaution do not treat very large breeds of dog with the
veterinary medicinal product until they are 18 months of age because of their longer
growth period.
Do not use in cats less than 8 weeks of age.
Do not use for prophylaxis.
Do not use in animals that are epileptic or suffer from seizures since enrofloxacin may
cause CNS stimulation. Do not use in cases of hypersensitivity to the active substance
or to any of the excipients.
Do not use when resistance / cross resistance to (fluoro)quinolones is known to occur.
Refer to section 3.5.
AN: 02463/2024 & 02464/2024 Page 3 of 8
Do not use in growing horses because of possible deleterious damage on articular
cartilage.
to the articular cartilage may occur during the period of rapid growth, specifically in
large breeds of dogs. As a precaution do not treat very large breeds of dog with the
veterinary medicinal product until they are 18 months of age because of their longer
growth period.
Do not use in cats less than 8 weeks of age.
Do not use for prophylaxis.
Do not use in animals that are epileptic or suffer from seizures since enrofloxacin may
cause CNS stimulation. Do not use in cases of hypersensitivity to the active substance
or to any of the excipients.
Do not use when resistance / cross resistance to (fluoro)quinolones is known to occur.
Refer to section 3.5.
AN: 02463/2024 & 02464/2024 Page 3 of 8
Do not use in growing horses because of possible deleterious damage on articular
cartilage.
Cattle (calves), Sheep, Goats, Pigs, Dogs, Cats
Very rare
(<1 animal / 10,000 animals
treated, including isolated
reports):
Injection site reaction
Digestive tract disorder (e.g. Diarrhoea)
Undetermined frequency,
(cannot be estimated from the
available data):
Injection site inflammation
, injection site reaction
(e.g. Oedema)
1
In calves; transient local tissue reactions may be observed up to 14 days.
Generally mild and transient.
In pigs; after intramuscular administration; may persist up to 28 days after the
injection.
In dogs; moderate and transient.
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder or its local representative or the national
competent authority via the national reporting system. See the package leaflet for
respective contact details.
Very rare
(<1 animal / 10,000 animals
treated, including isolated
reports):
Injection site reaction
Digestive tract disorder (e.g. Diarrhoea)
Undetermined frequency,
(cannot be estimated from the
available data):
Injection site inflammation
, injection site reaction
(e.g. Oedema)
1
In calves; transient local tissue reactions may be observed up to 14 days.
Generally mild and transient.
In pigs; after intramuscular administration; may persist up to 28 days after the
injection.
In dogs; moderate and transient.
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder or its local representative or the national
competent authority via the national reporting system. See the package leaflet for
respective contact details.
In dogs enrofloxacin may affect articular cartilage during the period of rapid growth.
Special precautions for safe use in the target species:
Enrofloxacin should be used with caution in epileptic animals or animals affected by
renal dysfunction.
Official and local antimicrobial policies should be taken into account when the
veterinary medicinal product is used.
Fluoroquinolones should be reserved for the treatment of clinical conditions which
have responded poorly, or are expected to respond poorly, to other classes of
antimicrobials.
Whenever possible, fluoroquinolones should only be used based on susceptibility
testing.
Use of the veterinary medicinal product deviating from the instructions given in the
SPC may increase the prevalence of bacteria resistant to the fluoroquinolones and
may decrease the effectiveness of treatment with other quinolones due to the potential
for cross resistance.
Degenerative changes of articular cartilage were observed in calves treated orally with
30 mg enrofloxacin/kg bw during 14 days.
The use of enrofloxacin in growing lambs at the recommended dose for 15 days
caused histological changes in the articular cartilage, not associated with clinical signs.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals:
The veterinary medicinal product is an alkaline solution. Direct contact with skin should
be avoided due to sensitisation, contact dermatitis and possible hypersensitivity
reactions to (fluoro)quinolones. Wear gloves. In case of eye or skin contact, rinse
immediately with water. Do not eat, drink or smoke whilst handling the veterinary
medicinal product.
Care should be taken to avoid accidental self-injection. If accidental self injection
occurs seek medical advice immediately and show the package leaflet or the label to
the physician.
Special precautions for the protection of the environment:
Not applicable.
AN: 02463/2024 & 02464/2024 Page 4 of 8
Special precautions for safe use in the target species:
Enrofloxacin should be used with caution in epileptic animals or animals affected by
renal dysfunction.
Official and local antimicrobial policies should be taken into account when the
veterinary medicinal product is used.
Fluoroquinolones should be reserved for the treatment of clinical conditions which
have responded poorly, or are expected to respond poorly, to other classes of
antimicrobials.
Whenever possible, fluoroquinolones should only be used based on susceptibility
testing.
Use of the veterinary medicinal product deviating from the instructions given in the
SPC may increase the prevalence of bacteria resistant to the fluoroquinolones and
may decrease the effectiveness of treatment with other quinolones due to the potential
for cross resistance.
Degenerative changes of articular cartilage were observed in calves treated orally with
30 mg enrofloxacin/kg bw during 14 days.
The use of enrofloxacin in growing lambs at the recommended dose for 15 days
caused histological changes in the articular cartilage, not associated with clinical signs.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals:
The veterinary medicinal product is an alkaline solution. Direct contact with skin should
be avoided due to sensitisation, contact dermatitis and possible hypersensitivity
reactions to (fluoro)quinolones. Wear gloves. In case of eye or skin contact, rinse
immediately with water. Do not eat, drink or smoke whilst handling the veterinary
medicinal product.
Care should be taken to avoid accidental self-injection. If accidental self injection
occurs seek medical advice immediately and show the package leaflet or the label to
the physician.
Special precautions for the protection of the environment:
Not applicable.
AN: 02463/2024 & 02464/2024 Page 4 of 8
Antagonistic effects due to concurrent administration of macrolides, tetracyclines and
phenicols may occur. Enrofloxacin may interfere with the metabolism of theophylline,
decreasing theophylline clearance resulting in increased plasma levels of theophylline.
Care should be taken during the concomitant use of flunixin and enrofloxacin in dogs
to avoid adverse drug reactions. The decrease in drug clearances as a result of co-
administration of flunixin and enrofloxacin indicates that these substances interact
during the elimination phase. Thus, in dogs, the co-administration of enrofloxacin and
flunixin increased the AUC and the elimination half-life of flunixin and increased the
elimination half-life and reduced the Cmax of enrofloxacin.
phenicols may occur. Enrofloxacin may interfere with the metabolism of theophylline,
decreasing theophylline clearance resulting in increased plasma levels of theophylline.
Care should be taken during the concomitant use of flunixin and enrofloxacin in dogs
to avoid adverse drug reactions. The decrease in drug clearances as a result of co-
administration of flunixin and enrofloxacin indicates that these substances interact
during the elimination phase. Thus, in dogs, the co-administration of enrofloxacin and
flunixin increased the AUC and the elimination half-life of flunixin and increased the
elimination half-life and reduced the Cmax of enrofloxacin.
Keep the vial in the outer carton in order to protect from light.
Cattle (calves):
Following intravenous injection: Meat and offal: 5 days.
Following subcutaneous injection: Meat and offal: 12 days.
Not authorised for use in animals producing milk for human consumption.
Sheep:
Meat and offal: 4 days.
Milk: 3 days.
Goats:
Meat and offal: 6 days.
Milk: 4 days.
Pigs:
Meat and offal: 13 days.
Following intravenous injection: Meat and offal: 5 days.
Following subcutaneous injection: Meat and offal: 12 days.
Not authorised for use in animals producing milk for human consumption.
Sheep:
Meat and offal: 4 days.
Milk: 3 days.
Goats:
Meat and offal: 6 days.
Milk: 4 days.
Pigs:
Meat and offal: 13 days.
This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.
Medication costs adding up?
Pet insurance can cover prescription medications. Find the right policy for your pet.
Related Conditions
Same active ingredient
Other Products Containing Enrofloxacin
These products share the same active ingredient and may be suitable alternatives. Always consult your vet.
Baytril 100 mg/ml Solution for Injection
POM-VElanco GmbH
injection
Cattle
Goats
Pigs
Baytril 100 mg/ml Solution for Injection
POM-VElanco GmbH
injection
Cattle
Goats
Pigs
Baytril 100 mg/ml Solution for use in Drinking Water for Chickens, Turkeys and Rabbits
POM-VElanco GmbH
solution
Chickens
Rabbits
Turkeys
Baytril 100 mg/ml Solution for use in Drinking Water for Chickens, Turkeys and Rabbits
POM-VElanco GmbH
solution
Chickens
Rabbits
Turkeys
Baytril 25 mg/ml Oral Solution
POM-VElanco GmbH
liquid
Cattle
Exotic Animal
Reptiles
Baytril 25 mg/ml Oral Solution
POM-VElanco GmbH
liquid
Cattle
Exotic Animal
Reptiles
Alternative options to consider
Retailers we earn a commission from. It costs you nothing and never changes what we show.
The Pharm Pet Co.
The Pharm Pet Co. — Pet Pharmacy
UK online pet pharmacy. Flea, worm, prescription medications, supplements and pet food. Save vs vet prices.
Save up to 50%
Shop now
Pharmacy2U
Pet Care at Pharmacy2U
The UK's largest online pharmacy. Pet wormers, flea treatments, dental and joint care. Free delivery on orders over £30.
Free delivery £30+
Shop now
Petlibro
Petlibro Automatic Feeder
Smart automatic pet feeder with app control. Schedule meals, portion control, and feeding history.
From £49.99
Shop now
We may earn a small commission if you purchase through these links, at no extra cost to you.
Also in antibiotic
Related Medications
Actionis 50 mg/ml, Suspension for Injection for Pigs and Cattle
POM-VCeftiofur
injection
Rx
Cattle
Pigs
Actionis 50 mg/ml, Suspension for Injection for Pigs and Cattle
POM-VCeftiofur
injection
Rx
Cattle
Pigs
Adaxio Shampoo for Dogs
POM-VChlorhexidine Gluconate + Miconazole Nitrate
shampoo
Rx
Dogs
Adaxio Shampoo for Dogs
POM-VChlorhexidine Gluconate + Miconazole Nitrate
shampoo
Rx
Dogs
Advocin 180, 180 mg/ml, Solution for Injection for Cattle
POM-VDanofloxacin
injection
Rx
Cattle
Aivlosin 42.5 mg/g Oral Powder for Pigs
POM-VTylvalosin
powder
Rx
Pigs
Find cheaper vets near you
Compare vet consultation prices in your area. Save on procedures and get a prescription to buy medications online.