Enrotron 25 mg/ml Solution for Injection for Dogs, Cats, Rodents, Reptiles and Ornamental Birds

Subcutaneous or intramuscular use.
Repeated injections should be made at different injection sites.
To ensure a correct dosage, body weight (bw) should be determined as accurately as
possible to avoid underdosing.
Dogs and cats
5 mg of enrofloxacin/kg bw, corresponding to 1 ml/5 kg bw, daily by subcutaneous
injection for up to 5 days.
Treatment may be initiated with injectable product and maintained with enrofloxacin
tablets. Duration of treatment should be based on the duration of treatment approved
for the appropriate indication in the product information of the tablet product.
Rodents
10 mg/kg bw, corresponding to 0.4 ml/kg bw, once daily by subcutaneous injection
for 5 to 10 consecutive days. If necessary, depending on the severity of clinical signs,
this dosage can be doubled.

Revised: February 2019
AN: 01476/2018
Reptiles
Reptiles are ectothermic, relying on external heat sources to maintain their body
temperature at the optimum level for correct function of all body systems. Metabolism
of substances and activity of the immune system are, thus, critically dependent on
the body temperature. Therefore, the veterinarian must be aware of the correct
temperature requirements of the respective reptile species and the hydration status
of the individual patient. Furthermore, it has to be considered that large differences
exist in the pharmacokinetic behaviour of enrofloxacin among different species, which
additionally will influence the decision about the correct dosage of Enrotron 25 mg/ml
Solution for injection.
Therefore, the recommendations made here can only be used as a starting point for
individual dose setting. 5–10 mg/kg bw, corresponding to 0.2–0.4 ml/kg bw, once
daily by intramuscular injection for 5 consecutive days.
An extension of the treatment interval to 48 hours may be necessary in individual
cases. In complicated infections, higher dosages and longer treatment courses may
be necessary. The presence of the renal portal system in reptiles means it is prudent
to administer substances in the front half of the body wherever possible.
Ornamental birds
20 mg/kg bw, corresponding to 0.8 ml/kg bw, once daily by intramuscular injection for
5 to 10 consecutive days. In case of complicated infections higher doses may be
necessary.
The use of a 0.5 ml (100 unit) insulin syringe should be considered for administration
of the small volumes required by some species of small animals (mice, gerbils etc.)
Treatment may be initiated with the injection and maintained with an enrofloxacin
containing oral solution.