Enrodexil 100 mg/ml Solution for Injection for Cattle and Pigs
Active ingredient: Enrofloxacin
Form
Injection
Species
Manufacturer
Industrial Veterinaria, S.A.
VMD MA No.
36547/4003
What it's used for
TreatmentTreatment ofof infectionsinfections ofof thethe alimentaryalimentary tracttract causedcaused byby enrofloxacinenrofloxacin susceptiblesusceptible...
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Enrodexil 100 mg/ml Solution for Injection for Cattle and Pigs — SPC Details
Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.
EscherichiaEscherichia colicoli..
TreatmentTreatment ofof septicaemiasepticaemia causedcaused byby enrofloxacinenrofloxacin susceptiblesusceptible strainsstrains ofof EscherichiaEscherichia colicoli..
TreatmentTreatment ofof acuteacute mycoplasma-associatedmycoplasma-associated arthritisarthritis duedue toto enrofloxacinenrofloxacin susceptiblesusceptible strainsstrains ofof
MycoplasmaMycoplasma bovisbovis inin cattlecattle lessless thanthan 22 yearsyears old.old.
Pigs
Treatment of infections of the respiratory tract caused by enrofloxacin susceptible strains of
Pasteurella multocida, Mycoplasma spp. and Actinobacillus pleuropneumoniae.
Treatment of infections of the urinary tract caused by enrofloxacin susceptible strains of
Escherichia coli.
Treatment of post-partum dysgalactiae syndrome, PDS (MMA syndrome) caused by
enrofloxacin susceptible strains of Escherichia coli and Klebsiella spp.
Treatment of infections of the alimentary tract caused by enrofloxacin susceptible strains of
Escherichia coli.
Treatment of septicaemia caused by enrofloxacin susceptible strains of Escherichia coli.
Enrofloxacin should be used where clinical experience, supported where possible by
sensitivity testing of the causal organism, indicates enrofloxacin as the drug of choice.
To ensure a correct dosage, body weight (bw) should be determined as accurately as
possible to avoid underdosing.
Cattle:
5 mg of enrofloxacin/kg bw, corresponding to 1 ml/20 kg bw, once daily for 3-5 days.
Acute mycoplasma-associated arthritis due to enrofloxacin susceptible strains of
bovis
bw, once daily for 5 days.
The product can be administered by slow intravenous or subcutaneous administration.
Not more than 10 ml should be administered at one subcutaneous injection site.
Pigs:
2.5 mg of enrofloxacin/kg bw, corresponding to 0.5 ml/20 kg bw, once daily by intramuscular
injection for 3 days.
Alimentary tract infection or septicaemia caused by : 5 mg of enrofloxacin/kg
bw, corresponding to 1 ml/20 kg bw, once daily by intramuscular injection for 3 days.
In pigs, the injection should be made in the neck at the ear base.
Not more than 3 ml should be administered at one intramuscular injection site.
The stopper should not be punctured more than 20 times.
Do not use when resistance / cross resistance to (Fluoro)quinolones is known to occur.
Refer to section 4.5.
Do not use in case of known hypersensitivity to fluoroquinolones or to any of the excipients.
Do not use in growing horses because of possible deleterious damage on articular cartilage.
should be taken.
In cattle, gastrointestinal disturbances may occasionally occur.
Special precautions for use in animals
Do not exceed the recommended dose.
Repeat injections should be administered at different sites.
Enrofloxacin should be used with caution in epileptic animals or animals affected by renal
dysfunction.
Degenerative changes of articular cartilage were observed in calves treated orally with 30 mg
enrofloxacin/kg bw during 14 days.
The use of enrofloxacin in growing lambs at the recommended dose for 15 days caused
histological changes in the articular cartilage, not associated with clinical signs.
Official and local antimicrobial policies should be taken into account when the product is used.
Fluoroquinolones should be reserved for the treatment of clinical conditions which have
responded poorly, or are expected to respond poorly, to other classes of antimicrobials.
Whenever possible, fluoroquinolones should only be used based on susceptibility testing.
Use of the product deviating from the instructions given in the SPC may increase the
prevalence of bacteria resistant to the fluoroquinolones and may decrease the effectiveness
of treatment with other quinolones due to the potential for cross resistance.
Special precautions to be taken by the person administering the veterinary medicinal product
to animals
The product is an alkaline solution. Wash any splashes from skin or eyes immediately with
water.
Do not eat, drink or smoke whilst using the product.
Care should be taken to avoid accidental self-injection. If accidental self injection occurs seek
medical advice immediately.
Direct contact with the skin should be avoided because of sensitisation, contact dermatitis
and possible hypersensitivity reactions. Wear gloves.
occur Enrofloxacin may interfere with the metabolism of theophylline, decreasing theophylline
clearance resulting in increased plasma levels of theophylline.
Do not freeze.
Do not use in growing horses because of possible deleterious damage on articular cartilage.
4.4. Special warnings, for each target species
None
4.5. Special precautions for use
Special precautions for use in animals
Do not exceed the recommended dose.
Repeat injections should be administered at different sites.
Enrofloxacin should be used with caution in epileptic animals or animals affected by renal
dysfunction.
Degenerative changes of articular cartilage were observed in calves treated orally with 30 mg
enrofloxacin/kg bw during 14 days.
The use of enrofloxacin in growing lambs at the recommended dose for 15 days caused
histological changes in the articular cartilage, not associated with clinical signs.
Official and local antimicrobial policies should be taken into account when the product is used.
Fluoroquinolones should be reserved for the treatment of clinical conditions which have
responded poorly, or are expected to respond poorly, to other classes of antimicrobials.
Whenever possible, fluoroquinolones should only be used based on susceptibility testing.
Use of the product deviating from the instructions given in the SPC may increase the
prevalence of bacteria resistant to the fluoroquinolones and may decrease the effectiveness
of treatment with other quinolones due to the potential for cross resistance.
Special precautions to be taken by the person administering the veterinary medicinal product
to animals
The product is an alkaline solution. Wash any splashes from skin or eyes immediately with
water.
Do not eat, drink or smoke whilst using the product.
Care should be taken to avoid accidental self-injection. If accidental self injection occurs seek
medical advice immediately.
Direct contact with the skin should be avoided because of sensitisation, contact dermatitis
and possible hypersensitivity reactions. Wear gloves.
4.
This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.
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