Enrocare 25 mg/ml Concentrate for Oral Solution for Pet Rabbits, Rodents, Ornamental Birds and Reptiles

For administration by gavage or in drinking water.
Dosage
Owing to physiological and pharmacokinetic differences between the wide range of
species for which this product is indicated, the dose rates below are for guidance
only. Depending upon the species of animal and the infection to be treated,
alternative doses may be appropriate using an evidence-based approach. However,
any change in dosing regimen should be based on a benefit:risk assessment by the
responsible veterinarian, as tolerance at higher doses has not been investigated.
Pet rabbits and rodents: 5 mg enrofloxacin per kg bodyweight (0.2 ml per kg
bodyweight) orally diluted in water, twice daily for 7 days.
Reptiles: 5 mg enrofloxacin per kg bodyweight (0.2 ml per kg bodyweight) orally
diluted in water, at 24-48 hour intervals for 6 days.
Reptiles are ectothermic, relying on external heat sources to maintain their body
temperature at the optimum level for correct function of all body systems. Metabolism
of substances and activity of the immune system are, thus, critically dependant on
the body temperature. Therefore, the veterinarian must be aware of correct
temperature requirements of the respective reptile species and the hydration status
of the individual patient. Furthermore, it has to be considered that large differences
exist in the pharmacokinetic behaviour of enrofloxacin among different species,
which additionally will influence the decision about the correct dosage of the
veterinary medicinal product. Therefore, the recommendations made here can only
be used as a starting point for individual dose setting.
Ornamental birds: 10 mg enrofloxacin per kg bodyweight (0.4 ml per kg
bodyweight), orally diluted in water, twice daily for 7 days.

Revised: August 2022
AN: 01024/2022Page 4 of 6
Information on correct administration
The undiluted veterinary medicinal product is strongly alkaline and, therefore, to
avoid caustic effects, it is essential to dilute the product with at least 4 parts water
prior to administration. In the case of smaller animals (weighing less than 500 g), it
may be appropriate to dilute 0.1 ml of the neat product with >4 parts water and
administer a proportion of the total volume.
If the product is to be given via the drinking water, concentrations of between 50 and
200 ppm should be considered as suitable working dilutions; concentrations in
excess of 250 ppm should be avoided as precipitation may occur.
Medicated fluids should be made up immediately prior to provision on a daily basis.
20 ml bottle: A 3 ml syringe is provided with the 20 ml bottle for withdrawal of the
product and facilitation of dilution prior to administration. This syringe has
graduations of 0.1 ml. It is recommended to draw up a minimum of 0.1 ml of product
prior to dilution since it is not possible to accurately measure volumes that are lower
than this.
100 ml bottle: A 10 ml syringe is provided with the 100 ml bottle for withdrawal of the
product and facilitation of dilution prior to administration. This syringe has
graduations of 0.2 ml. It is recommended to draw up a minimum of 0.2 ml of product
prior to dilution since it is not possible to accurately measure volumes that are lower
than this.
To withdraw product, firmly insert the syringe hub into the centre of the self-sealing
syringe adaptor of the bottle and remove the required amount.
To avoid inhalation of the medication, care should be taken with restraint of the
animal and administration of the product.