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AVM-GSL Over the Counter Companion Animal

Capstar 57 mg Tablets for Large Dogs

Active ingredient: Nitenpyram

Form

Tablet

Species

Dogs

Manufacturer

Elanco GmbH

VMD MA No.

52127/3023

What it's used for

Treatment of flea infestations (C. felis).

Full indications, dosage and side effects ↓
View official SPC (PDF)

The prescription itself has a price. See what practices near you charge for a consultation and the written prescription fee.

Paying less for Nitenpyram

  1. 1

    Ask your vet for a written prescription

    They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.

  2. 2

    Fill it at a registered online retailer

    The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

Clinical information

Capstar 57 mg Tablets for Large Dogs — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

Treatment of flea infestations (C. felis).
The minimum effective recommended dose is 1 mg/kg, with the following
recommendations:
One tablet should be given to dogs weighing 11.1 kg to 57.0 kg and two tablets for
dogs weighing over 57 kg when a flea infestation is detected. The frequency of
treatment depends on the degree of infestation. In the case of a severe flea
infestation, it may be necessary to treat the animals every day or every other day,
until the flea infestation is controlled. Treatment may be resumed if fleas reappear.
No more than one treatment should be given per day.
Tablets should be given orally, with or without food. In order to improve palatability,
tablets can be disguised in a small quantity of food immediately prior to
administration.
The veterinary medicinal product does not have persistent activity. To prevent re-
infestation, a suitable treatment to control immature stages of the flea life cycle is
recommended. The veterinary surgeon should establish an appropriate treatment
regime.
None.
Dogs:
Very rare
(<1 animal / 10 000 animals
treated, including isolated
reports):
Excessive chewing, licking and/or grooming
,
Hyperactivity, Vocalisation
Neurological signs (e.g., muscle tremor, ataxia,
convulsion)
Panting
Increased scratching
1
Transient
For the first hour following administration; presumably caused by flea response to
the veterinary medicinal product.
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder or its local representative or the national
competent authority via the national reporting system. See the package leaflet for
respective contact details.
None.

Special precautions for safe use in the target species:
Do not use on dogs weighing less than 11 kg.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals:
None.
Special precautions for the protection of the environment:
Not applicable.
None known.
No adverse drug reactions were seen in clinical studies when nitenpyram was
administered with other veterinary medicinal products including commonly used flea
products, anthelmintics, vaccines or antibiotics.
Do not store above 25 C.
Not applicable.
4.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.

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