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POM-V Prescription Required Companion Animal

Butasal 100 mg/ml + 0.05 mg/ml Solution for Injection for Horses, Cattle, Dogs and Cats

Active ingredients: Butafosfan, Cyanocobalamin

Form

Injection

Species

Cats Cattle Dogs Horses

Manufacturer

Interchemie Werken De Adelaar Eesti AS

VMD MA No.

51467/4002

What it's used for

AN: 02166/2024 & 02168/2024 Cattle: - Supportive treatment to restore rumination following surgical treatment of displaced abomasum associated with seconda...

Full indications, dosage and side effects ↓
View official SPC (PDF)

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Paying less for Butafosfan + Cyanocobalamin

  1. 1

    Ask your vet for a written prescription

    They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.

  2. 2

    Fill it at a registered online retailer

    The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Butasal 100 mg/ml + 0.05 mg/ml Solution for Injection for Horses, Cattle, Dogs and Cats — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

AN: 02166/2024 & 02168/2024
Cattle:
- Supportive treatment to restore rumination following surgical treatment of displaced
abomasum associated with secondary ketosis.
- Complementary treatment of parturient paresis in addition to Ca/Mg therapy.
- Prevention of ketosis development, if administered before calving.
Horses:
- Adjunctive therapy in horses suffering from muscular exhaustion.
Dogs: for intravenous (i.v.), intramuscular (i.m.), subcutaneous (s.c.) use.
It is recommended that the solution is warmed to body temperature before
administration.
The dose depends on the animal’s body weight (bw) and condition.
Species
Dose butafosfan
(mg/kg bw)
Dose
cyanocobalamin
(mg/kg bw)
Dose volume of
the veterinary
medicinal
product
Route of
administration
Cattle
Horses
5–100.0025–0.0055–10 ml/100 kgi.v.
Dogs10–150.005–0.00750.1–0.15 ml/kgi.v., i.m., s.c.
AN: 02166/2024 & 02168/2024
For the supportive treatment of secondary ketosis in cows, the recommended dose
should be administered on three consecutive days.
For the prevention of ketosis in cows, the recommended dose should be
administered on three consecutive days within the period of 10 days before expected
calving.
For other indications, treatment should be repeated as necessary.
The cap may be safely punctured up to 15 times.
Do not use in cases of hypersensitivity to the active substance(s) or to any of the
excipient(s).
Horses, cattle and dogs:
Rare
(1 to 10 animals / 10,000 animals treated):
Injection site pain
Very rare
(<1 animal / 10,000 animals treated,
including isolated reports):
Circulatory shock
1
Has been reported following subcutaneous administration in dogs.
In cases where rapid intravenous infusion has occurred.
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder or the national competent authority via the
national reporting system. See the package leaflet for respective contact details.
It is recommended to determine the cause(s) of the metabolic or reproductive
disorders to define the most appropriate measures of prevention and treatment and
the need for a therapy with supplemental phosphorus and vitamin B12.

Special precautions for safe use in the target species:
Intravenous administration should be done very slowly since cases of circulatory
shock may be associated with too rapid injection.
In dogs suffering from chronic renal insufficiency the veterinary medicinal product
should only be used according to the benefit-risk assessment by the responsible
veterinarian.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals:
Benzyl alcohol may cause hypersensitivity (allergic reactions). People with known
hypersensitivity to benzyl alcohol or any of the excipients should avoid contact with
the veterinary medicinal product.
This veterinary medicinal product may cause skin and eye irritation. Avoid contact
with skin and eyes. In case of accidental exposure, rinse the affected area thoroughly
with water.
Self-injection should be avoided. In case of accidental self-injection, seek medical
advice immediately and show the package leaflet or the label to the physician.
Wash hands after use.
AN: 02166/2024 & 02168/2024
Special precautions for the protection of the environment:
Not applicable
None known.
Do not store above 25 °C.
Keep the vial in the outer carton in order to protect from light.
Cattle, horses:
Meat and offal: zero days
Milk: zero hours

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.

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