Addimag 160 mg/ml + 84 mg/ml Solution for Infusion for Cattle
Active ingredients: Calcium Gluconate Monohydrate, Magnesium Chloride Hexahydrate
Form
Solution
Species
Manufacturer
Alfasan Nederland B.V.
VMD MA No.
36408/4003
What it's used for
For the treatment of hypocalcaemia in cattle
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Addimag 160 mg/ml + 84 mg/ml Solution for Infusion for Cattle — SPC Details
Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.
individual deficit and actual circulatory conditions.
Administer approximately 15 - 20 mg Ca
2+
(0.37 – 0.49 mmol Ca
2+
) and 10 – 13 mg
Mg
2+
(0.41 - 0.53 mmol Mg
2+
) per kg bodyweight corresponding to approximately 1.0
- 1.4 ml of product per kg bodyweight.
If the animal’s weight cannot be determined accurately, but has to be estimated, the
following approach might be used:
Bottle size (ml)Weight (kg)Ca
2+
(mg/kg)Mg
2+
(mg/kg)500350-47515.1 – 20.4 10.5 – 14.3750500-72514.8 – 21.5 10.3 – 15.0
The intravenous infusion must be executed slowly over a period of 20-30 minutes.
After a minimum of 6 hours after treatment, a second treatment may be administered.
The administration can be repeated twice at 24-hour intervals, if the hypocalcaemic
condition is persisting.
Do not use in cases of calcinosis in cattle.
Do not use following administration of high doses of vitamin D3.
Do not use in cases of chronic kidney insufficiency or in cases of circulatory or
cardiac disorders.
AN: 04352/2024 & 04355/2024Page 2 of 6
Do not use in cases of septicaemic processes in the course of acute mastitis in cattle.
Undetermined frequency
(cannot be estimated from
available data)
Hypercalcaemia
1,2
;
increased respiratory rate
1,2
;
bradycardia
1,2
, tachycardia
1,2,3
, arrhythmia
1,2,4
;
muscle tremor
1,2
;
increased salivation
1,2
.
too rapid administration of the product may cause these effects.
transient.
increase in heart rate following initial bradycardia may indicate that overdosing has
occurred. In this case the administration should be stopped immediately.
especially ectopic ventricular beats.
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder or its local representative or the national
competent authority via the national reporting system. See the package leaflet for
respective contact details.
Special precautions for safe use in the target species:
The medicinal product must be administered slowly, at body temperature.
During infusion, the heart rate, rhythm and circulation must be monitored. In case of
symptoms of overdosing (bradycardia, cardiac arrhythmia, fall in blood pressure,
agitation), the infusion should be stopped immediately.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals:
Not applicable.
Special precautions for the protection of the environment:
Not applicable.
these drugs are given together.
Calcium amplifies the cardiac effects of drugs and methylxanthines.
Glucocorticoids increase the renal excretion of calcium by way of vitamin D
antagonism.
Do not administer inorganic phosphate solutions simultaneously or shortly after the
infusion.
After a minimum of 6 hours after treatment, a second treatment may be administered.
The administration can be repeated twice at 24-hour intervals, if the hypocalcaemic
condition is persisting.
3.10 Symptoms of overdose (and where applicable, emergency procedures and
antidotes)
When the intravenous administration is performed too rapidly, hypercalcaemia and/or
hypermagnesemia with cardiotoxic symptoms such as initial bradycardia with
subsequent tachycardia, cardiac arrhythmia and in severe cases ventricular
fibrillation with cardiac arrest may occur.
Additional symptoms of hypercalcaemia are: motor weakness, muscle tremors,
increased excitability, agitation, sweating, polyuria, fall in blood pressure, depression
and coma.
Symptoms of hypercalcaemia may persist 6 – 10 hours after the infusion and must
not be incorrectly diagnosed as symptoms of hypocalcaemia.
AN: 04352/2024 & 04355/2024Page 4 of 6
3.11 Special restrictions for use and special conditions for use, including
restrictions on the use of antimicrobial and antiparasitic veterinary
medicinal products in order to limit the risk of development of resistance
Not applicable.
3.12 Withdrawal periods
Meat and offal: Zero days
Milk: Zero hours
4.
This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.
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Other Products Containing Calcium Gluconate Monohydrate
These products share the same active ingredient and may be suitable alternatives. Always consult your vet.
Addimag 240 mg/ml + 126 mg/ml Solution for Infusion for Cattle
POM-VAlfasan Nederland B.V.
Calcibel 240/60/60 mg/ml Solution for Infusion for Horses, Cattle, Sheep, Goats and Pigs
POM-VBela-Pharm GmbH & Co. KG
Calcibel Forte, 380/60/50 mg/ml Solution for Infusion for Horses, Cattle, Sheep, Goats and Pigs
POM-VBela-Pharm GmbH & Co. KG
Calmino Vet 380 mg/ml + 60 mg/ml + 50 mg/ml Solution for Infusion for Cattle, Sheep and Pigs
POM-VInterchemie Werken De Adelaar Eesti AS
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