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POM-V Prescription Required Companion Animal

Aqupharm 11 (Hartmann's) Solution for Infusion

Active ingredients: Calcium Chloride Dihydrate, Potassium Chloride, Sodium Chloride, Sodium Lactate

Form

Solution

Species

Cats Cattle Dogs Goats Horses Pigs Rabbits Sheep

Manufacturer

Ecuphar NV

VMD MA No.

32742/4020

What it's used for

Treatment and prevention of perioperative hypovolaemia and haemorrhagic shock. Treatment of mild metabolic acidosis. AN: 00141/2025 & 00142/2025Page 2 of 7

Full indications, dosage and side effects ↓
View official SPC (PDF)

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Prescription required

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Clinical information

Aqupharm 11 (Hartmann's) Solution for Infusion — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

Treatment and prevention of perioperative hypovolaemia and haemorrhagic shock.
Treatment of mild metabolic acidosis.
AN: 00141/2025 & 00142/2025Page 2 of 7
Management of dehydration including patients with mild metabolic acidosis
The amount of fluid and electrolytes to be administered should be calculated by
adding the existing deficits to the ongoing maintenance requirements and any
ongoing fluid losses (e.g. from ongoing vomiting, diarrhoea etc) estimated from the
history of the animal, clinical examination and laboratory findings.
AN: 00141/2025 & 00142/2025Page 4 of 7
To calculate the existing fluid deficit, the following equation should be used;
Fluid deficit (mls) = Percentage dehydration x Bodyweight (kg) x 10
(e.g. for a 10 kg dog with 5 % dehydration the fluid deficit would be 5 x 10 x 10 =
500 ml)
To calculate the ongoing maintenance requirement, the following equation should be
used;
Maintenance for cattle, horses, sheep, goats, pigs, dogs and cats (mls) = 50 ml x
Bodyweight (kg) per day
Maintenance for rabbits (mls) = 75-100 ml x Bodyweight (kg) per day
(e.g. for a 10 kg dog, the daily maintenance fluid requirement is 10 x 50 = 500 ml)
The administration rate should be adjusted to each animal. The objective is to correct
the deficit over 12 – 24 hours.
Prevention of peri-operative hypovolaemia
Administer at a rate of 5 – 10 ml/kg/h during anaesthesia.
Treatment of hypovolaemic and haemorrhagic shock
Cattle, horses, sheep, goats, pigs, dogs, rabbits: up to 90 ml/kg/h
Cats: up to 60 ml/kg/h
High infusion rates should not be continued for longer than 1 hour.
Do not use in cases of:








Cattle, horses, sheep, goats, pigs, dogs, cats and rabbits:
Undetermined frequency (cannot be
estimated from the available data):
Alkalosis
1
In cases of excessive administration or impaired metabolism of lactate.
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder or its local representative or the national
competent authority via the national reporting system. See the package leaflet for
respective contact details.
None.

Special precautions for safe use in the target species:
Maintain aseptic precautions.
Do not use unless the solution is clear, free from visible particles, and the container is
undamaged. A risk of thrombosis with intravenous infusion should be considered.
This veterinary medicinal product does not contain an antimicrobial preservative. It is
intended for single use only and any unused contents should be discarded.
The solution should be warmed to approximately to 37 °C prior to the administration
of large volumes, or if the administration rate is high, in order to avoid hypothermia.
The volume and infusion rate must be adapted to the clinical status of each animal.
This veterinary medicinal product should be used with caution in animals with cardiac
or renal impairment as sodium overload may occur. It should be noted that sodium
excretion may be impaired post-surgery/trauma.
Use of this solution requires monitoring of the clinical and physiological status of the
animal especially in cases of:




Monitor serum potassium and serum calcium in treated animals, particularly
potassium levels in cases at risk of hyperkalaemia, such as during chronic renal
failure.
In animals with hepatic impairment, the veterinary medicinal product may not
produce its alkalising action since lactate metabolism may be altered.
AN: 00141/2025 & 00142/2025Page 3 of 7
Do not inject intramuscularly.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals
Not applicable.
Special precautions for the protection of the environment:
Not applicable.
Interactions linked to calcium.
In case of concomitant blood transfusion, the veterinary medicinal product should not
be administered with the blood in the same infusion set due to the risk of clotting.
This veterinary medicinal product contains calcium. Do not add drugs to this solution
that may bind (chelate) to calcium.
250 ml: Store below 25 °C.
AN: 00141/2025 & 00142/2025Page 6 of 7
500 ml, 1000 ml, 3000 ml, 50000 ml: This veterinary medicinal product does not
require any special storage conditions.
Meat and offal: zero days.
Milk: zero hours.
AN: 00141/2025 & 00142/2025Page 5 of 7

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.

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