POM-V Prescription Required Companion Animal

Buscopan Compositum Solution for Injection

Active ingredients: Hyoscine Butylbromide, Metamizole

Form

Injection

Species

Cattle Dogs Horses

Manufacturer

Boehringer Ingelheim Animal Health UK Limited

VMD MA No.

08327/5060

What it's used for

As an aid in the control of pain associated with simple equine colic and as a diagnostic aid in more severe equine colics. For the control of diarrhoea in...

Full indications, dosage and side effects ↓

View official SPC (PDF)

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1

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2

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Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Buscopan Compositum Solution for Injection — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 18 Mar 2026.

As an aid in the control of pain associated with simple equine colic
and as a diagnostic aid in more severe equine colics.
For the control of diarrhoea in cattle, horses and dogs particularly
when pain or abdominal discomfort is present.
For the control of pain associated with urinary obstruction in horses
and dogs.

Use aseptic techniques.
Horses 5 ml Buscopan Compositum per 100 kg body weight by
intravenous injection only.
Adult Cattle 5 ml Buscopan Compositum per 100 kg body weight by
intravenous or intramuscular injection
Dogs 0.1 ml Buscopan Compositum per kg body weight by
intravenous or intramuscular injection

Due to a risk of local reactions do not use the intramuscular route in horses.
Do not use in case of hypersensitivity to the active substance or to any of the
excipients.
Do not use in horses suffering from paralytic ileus.

In horses, a slight transient increase in heart rate may be observed due to
the parasympatholytic activity of butylscopolaminiumbromide (hyoscine
butylbromide). In very rare cases, cardiovascular shock may occur if the
intravenous injection is administered too fast.
In horses, mild tachycardia may be observed occasionally due to the
parasympatholytic activity of hyoscine butylbromide.
In very rare cases, anaphylactic reactions may occur and should be treated
symptomatically.
The frequency of adverse reactions is defined using the following
convention:

reaction(s))

treated)

treated)


isolated reports).

None

Revised: August 2025
MA split from NI MA following AN: 01364/2025Page 2 of 5

(i) Special precautions for use in animals
Due to the risk of anaphylactic shock metamizole-containing solutions should
be administered slowly when given intravenously.
(ii) Special Precautions to be taken by the person administering the
product to animals
Take care to avoid self-injection. In a very small number of people,
metamizole can cause reversible, but potentially serious agranulocytosis and
other reactions such as skin allergy. Avoid use of the product if you are
known to be sensitive to pyrazolones, or are sensitive to aspirin. Wash any
splashes from the skin. If accidental self-injection occurs, seek medical
advice and show the Doctor the product packaging.

interaction.
The effects of metamizole and/or butylscopolamine bromide may be
potentiated by concurrent use of other anticholinergic or analgesic drugs.
Concomitant use of inducers of hepatic microsomal enzymes (e.g.,
barbiturates, phenylbutazone) reduces the half-life period and hence the

Revised: August 2025
MA split from NI MA following AN: 01364/2025Page 3 of 5
duration of action of metamizole. Simultaneous administration of
neuroleptics, especially phenothiazine derivatives, may lead to severe
hypothermia. Furthermore, the risk of gastro-intestinal bleeding is increased
upon concurrent use of glucocorticoids. The diuretic effect of furosemide is
attenuated.
Co-administration of other weak analgesics increases the effects and side-
effects of metamizole.
The anticholinergic action of quinidine and antihistaminic as well as the
tachycardic effects of β sympathomimetics may be enhanced by this
veterinary medicinal product.

Do not store above 25°C.
Protect from light.
Keep the container in the outer carton.

Meat and Offal
Horses – 12 days
Cattle - 9 days after i.v. injection, 28 days after i.m. injection.
Not to be used in cows producing milk for human consumption.
5.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.