Bravecto 1 400 mg Spot-on Solution for Very Large Dogs (>40 – 56 kg)

Parasites need to start feeding on the host to become exposed to fluralaner;
therefore the risk of the transmission of parasite borne diseases cannot be excluded.
Unnecessary use of antiparasitics or use deviating from the instructions given in the
SPC may increase the resistance selection pressure and lead to reduced efficacy.
The decision to use the veterinary medicinal product should be based on
confirmation of the parasitic species and burden, or of the risk of infestation based on
its epidemiological features, for each individual animal.
The possibility that other animals in the same household can be a source of re-
infection with parasites should be considered, and these should be treated as
necessary with an appropriate veterinary medicinal product.

Special precautions for use in animals:
Care should be taken to avoid contact with the eyes of the animal.
Do not use directly on skin lesions.
Do not wash or allow the dog to become immersed in water or swim in water courses
within 3 days after treatment.
In the absence of available data, this veterinary medicinal product should not be used
on puppies less than 8 weeks old and /or dogs weighing less than 2 kg.
The veterinary medicinal product should not be administered at intervals shorter than
8 weeks as the safety at shorter intervals has not been tested.
This veterinary medicinal product is for topical use and should not be administered
orally.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals:
Contact with the veterinary medicinal product should be avoided and disposable
protective gloves obtained with this veterinary medicinal product at the point of sale
must be worn when handling the veterinary medicinal product for the following
reasons:
Hypersensitivity reactions have been reported in a small number of people, which
can potentially be serious.
Persons with a hypersensitivity to fluralaner or to any of the excipients should avoid
any exposure to the veterinary medicinal product.
The veterinary medicinal product binds to skin and may also bind to surfaces after
spillage of the veterinary medicinal product. Skin rashes, tingling or numbness have
been reported in a small number of individuals after skin contact.

Amended Pages: September 2025
AN: 00732/2025
If skin contact does occur, wash the affected area immediately with soap and water.
In some cases, soap and water are not sufficient to remove the veterinary medicinal
product spilled on the fingers.
Contact with the veterinary medicinal product may also occur when handling the
treated animal.
Make sure that your animal’s application site is no longer noticeable before resuming
contact with the site of application. This includes cuddling the animal and sharing a
bed with the animal. It takes up to 48 hours for the application site to become dry but
it will be noticeable for longer.
If skin reactions occur, consult a physician and show them the veterinary medicinal
product packaging.
People with a sensitive skin or known allergy in general e.g. to other veterinary
medicinal products of this type should handle the veterinary medicinal product as well
as treated animals with caution.
This veterinary medicinal product can cause eye irritation. In case of contact with the
eyes, immediately rinse thoroughly with water.
This veterinary medicinal product is harmful after ingestion. Keep the veterinary
medicinal product in the original packaging until use, in order to prevent children from
getting direct access to the veterinary medicinal product. A used pipette should
immediately be disposed of. In case of accidental ingestion, seek medical advice and
show the package leaflet or the label to the physician.
The veterinary medicinal product is highly flammable. Keep away from heat, sparks,
open flame or other sources of ignition.In case of spillage onto, for example table or
floor surfaces, remove excess veterinary medicinal product using paper tissue and
clean the area with detergent.
Special precautions for the protection of the environment:
Treated dogs should not be allowed to enter surface water for 48 hours after
treatment to avoid adverse effects on aquatic organisms.
Other precautions:
Not applicable.