API-Bioxal 44.2 mg/ml Bee-Hive Solution

For greatest efficacy, the product should only be used when the quantity of brood in
the colony is non-existent or at its lowest levels. Oxalic acid does not penetrate wax
so will not kill mites within capped brood and therefore the presence of brood may
noticeably reduce the efficacy of the product. As such, the product should be used in
winter or following manipulation of the colony to produce a broodless state in summer
(e.g. by queen caging).
With regard to summer treatments following queen caging, highest levels of efficacy
were achieved when a caging period of at least 25 days was used, at which point the

Issued: July 2023
AN: 02839/2021
colonies were completely broodless. Despite proper treatment, seriously damaged
colonies may not survive due to the effects of varroa infestation.
All colonies in the same apiary should be treated simultaneously to avoid
reinfestations.
Integrated Pest Management Programme
The efficacy may vary between colonies due to the conditions of use (residue presence
of brood, temperature, reinfestations etc.). The product should therefore be used as a
treatment amongst others within an Integrated Pest Management program, and mite
drop regularly monitored.

i). Special precautions for use in animals
Administer the treatment without supers. Avoid disturbance to the hives during the
days after the treatment.
ii). Special precautions to be taken by the person administering the veterinary
medicinal product to animals
This product is a highly acidic solution that may cause severe irritation to the skin and
eyes. Avoid contact with the skin, eyes and mucous membranes. When handling the
product wear protective clothing, chemical-resistant gloves, and safety glasses. After
application, wash hands with soap and water and thoroughly wash any clothing that
comes into contact with the product. In case of accidental spillage onto the skin, wash
the affected areas immediately with running water. In case of accidental eye contacts,
flush the eyes immediately with clear running water for 10 minutes.
Accidental ingestion may cause severe adverse reactions. Children should not come
into contact with this veterinary medicinal product. In case of accidental ingestion,
clean mouth with water and drink plenty of water or milk. Do not induce vomiting. Seek
medical advice immediately.
Do not eat, drink or smoke while handling the product.
Special precautions for the protection of the environment: Not applicable.
iii). Other precautions
None