Advantage 80 mg Spot-on Solution for Large Cats and Pet Rabbits

Re-infestation from emergence of new fleas in the environment may continue to
occur for six weeks or longer after treatment is initiated. To aid reduction in
environmental challenge, the additional use of a suitable environmental
treatment against adult fleas and their developing stages is recommended. In
order to reduce further the environmental challenge, it is recommended that all
dogs, cats and rabbits in the household are treated, as necessary, with an
appropriate product. Treatment of nursing queens controls flea infestations on
both dam and offspring.
The veterinary medicinal product remains effective if the animal becomes wet,
for example after exposure to heavy rain. However, re-treatment may become
necessary, depending on the presence of fleas in the environment. In these
cases do not treat more frequently than once weekly.
Unnecessary use of antiparasitics or use deviating from the instructions given in
the SPC may increase the resistance selection pressure and lead to reduced
efficacy. The decision to use the product should be based on confirmation of the
parasitic species and burden, or of the risk of infestation based on its
epidemiological features, for each individual animal.

Special precautions for safe use in the target species:
This veterinary medicinal product is for topical use and should not be
administered orally.
Apply only to undamaged skin.
Care should be taken to avoid the contents of the tube coming into contact with
the eyes or mouth of the recipient animal.
Do not allow recently treated animals to groom each other.
Any collar should be removed prior to application of the veterinary medicinal
product. Prior to re-fitting the collar, the treated area should be visually assessed
to ensure it is dry.
Special precautions to be taken by the person administering the veterinary
medicinal product to animals
Keep stored tubes in the original packaging until ready to use. In order to
prevent children from getting access to used tubes, dispose of used tubes
immediately.
People with known hypersensitivity to imidacloprid should avoid contact with the
veterinary medicinal product.
This product contains benzyl alcohol and may cause sensitisation or transient
skin reactions (e.g. irritation, tingling).
Avoid contact between the veterinary medicinal product and skin, eyes or mouth.
Do not massage the application site.
If the veterinary medicinal product gets into eyes, flush thoroughly with water.
If skin or eye irritation persists or the veterinary medicinal product is accidentally
swallowed, seek medical advice immediately and show the package leaflet or
the label to the physician.
Do not eat, drink or smoke during application.
Wash hands thoroughly after use.
Wash off any skin contamination with soap and water.
After application, do not stroke or groom treated animals until the application site
is dry (typically within an hour or so). It is therefore recommended that animals
are not treated during the day, but should be treated during the early evening,
and that recently treated animals are not allowed to sleep with owners,
especially children.
Special precautions for the protection of the environment:
Not applicable
Other precautions:
The solvent in this veterinary medicinal product may stain or damage certain
materials including leather, fabrics, plastics and finished surfaces. Allow the
application site to dry before permitting contact with such materials.