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Cytopoint vs Atopica

A detailed comparison of Cytopoint and Atopica for dogs. Which is the better choice? We compare ingredients, dosing, price, and side effects.

Cytopoint

Lokivetmab injection — a monoclonal antibody that targets and neutralises IL-31 (the itch cytokine). Given at the vet every 4–8 weeks.

Ingredient Lokivetmab
Form Injection
Frequency Every 4–8 weeks (vet visit)
Price range £50–£120/injection

Atopica

Ciclosporin capsules — an oral immunosuppressant for long-term control of atopic dermatitis.

Ingredient Ciclosporin
Form Soft capsule
Frequency Daily (can reduce to alternate days)
Price range £2–£5/day
Buy with a vet prescription

Save on Cytopoint or Atopica at a UK pharmacy

UK registered pharmacies dispense the same prescription medications as your vet, often for less. Ask your vet for a written prescription, then fill it online.

Affiliate links to The Pharm Pet Co., a UK registered veterinary pharmacy. We may earn a small commission, at no extra cost to you. Always follow your vet's guidance on medication choice and dosing.

Side-by-Side Comparison

Feature Cytopoint Atopica
Active Ingredient Lokivetmab Ciclosporin
Form Injection Soft capsule
Frequency Every 4–8 weeks (vet visit) Daily (can reduce to alternate days)
Species Dogs Dogs
Price Range £50–£120/injection £2–£5/day

Key Differences

Convenience

Cytopoint is a vet injection (no daily pills); Atopica is daily oral capsules.

Immune safety

Cytopoint does not suppress immunity; Atopica broadly suppresses T-cell function.

Cost

Atopica (especially generic Sporimmune) is cheaper for most dog sizes. Cytopoint is expensive for large dogs.

Time to effect

Cytopoint works in 1–3 days; Atopica takes 4–6 weeks.

Monitoring

Cytopoint needs no blood tests; Atopica requires periodic liver/kidney monitoring.

Pros & Cons

Cytopoint

Pros

  • No daily pills needed
  • Minimal side effects — no immune suppression
  • No blood monitoring needed
  • Very safe long-term profile

Cons

  • Requires vet visit every 4–8 weeks
  • More expensive overall
  • Takes 1–3 days to work
  • Not available from online online retailers

Atopica

Pros

  • Can manage at home — no vet visits for dosing
  • Generic versions (Sporimmune) much cheaper
  • Can reduce to alternate-day dosing
  • Available from online online retailers with prescription

Cons

  • Daily dosing — easy to forget
  • GI side effects common initially
  • Takes 4–6 weeks to work fully
  • Broader immune suppression — blood monitoring needed

Compare Prices & Save

Both Cytopoint and Atopica may be cheaper from a licensed online retailer than from your vet. Ask for a written prescription and compare prices.

Important: This comparison is for informational purposes only and is not veterinary advice. Always consult your vet before starting, stopping, or switching your pet's medication. Prices shown are typical UK ranges and may vary by product size, weight band, and retailer.