Bravecto vs Frontline Plus
A detailed comparison of Bravecto and Frontline Plus for dogs. Which is the better choice? We compare ingredients, dosing, price, and side effects.
Bravecto
Long-lasting chewable flea and tick tablet for dogs. One dose of fluralaner provides protection for a full 12 weeks.
Frontline Plus
Monthly spot-on flea and tick treatment containing fipronil and (S)-methoprene. One of the most widely used flea treatments in the UK.
Save on Bravecto or Frontline Plus at a UK pharmacy
UK registered pharmacies dispense the same prescription medications as your vet, often for less. Ask your vet for a written prescription, then fill it online.
Affiliate links to The Pharm Pet Co., a UK registered veterinary pharmacy. We may earn a small commission, at no extra cost to you. Always follow your vet's guidance on medication choice and dosing.
Side-by-Side Comparison
| Feature | Bravecto | Frontline Plus |
|---|---|---|
| Active Ingredient | Fluralaner | Fipronil + (S)-Methoprene |
| Form | Chewable tablet | Spot-on pipette |
| Frequency | Every 12 weeks | Monthly |
| Species | Dogs | Dogs |
| Price Range | £18–£40/12 weeks | £4–£10/month |
Key Differences
Duration
Bravecto lasts 12 weeks per dose; Frontline needs monthly application.
Convenience
Bravecto means only 4–5 doses per year versus 12 with Frontline.
Access
Bravecto needs a vet prescription; Frontline is available over the counter.
Effectiveness
Bravecto uses a newer ingredient with no known resistance; Frontline has reported resistance issues.
Annual cost
Bravecto: £72–£160/year. Frontline Plus: £48–£120/year.
Pros & Cons
Bravecto
Pros
- One dose lasts 12 weeks — much less hassle
- Oral tablet — no messy spot-on
- Very fast flea kill within hours
- No bathing restrictions
Cons
- Prescription only (POM-V)
- Cannot stop quickly if side effects occur
- More expensive per dose (though fewer doses needed)
- Does not kill flea eggs or larvae directly
Frontline Plus
Pros
- No prescription needed — buy at any pet shop
- Cheapest option on the market
- Kills flea eggs and larvae (lifecycle control)
- Decades of safe use history
Cons
- Monthly spot-on application needed
- Growing flea resistance to fipronil reported
- Greasy residue on coat for 24–48 hours
- Must avoid bathing for 48 hours
Compare Prices & Save
Both Bravecto and Frontline Plus may be cheaper from a licensed online retailer than from your vet. Ask for a written prescription and compare prices.
Important: This comparison is for informational purposes only and is not veterinary advice. Always consult your vet before starting, stopping, or switching your pet's medication. Prices shown are typical UK ranges and may vary by product size, weight band, and retailer.
Alternative options to consider
Retailers we earn a commission from. It costs you nothing and never changes what we show.
Flea & Tick Treatments for Dogs
Vet-strength flea and tick treatments at pharmacy prices. Frontline, Advocate, Bravecto, Nexgard and more.
Pet Flea Treatments at Pharmacy2U
Frontline, Advantage and own-brand flea treatments at pharmacy prices. Trusted UK pharmacy since 1999.
VetBox Flea & Worm Protection for Dogs
Vet-founded monthly parasite subscription. Flea, tick and worm protection delivered to your door. Founded by Dr Will Woodley, protecting 30,000+ pets.
We may earn a small commission if you purchase through these links, at no extra cost to you.