POM-V Prescription Required

Zactran 150 mg/ml Solution for Injection for cattle, sheep and pigs

Active ingredient: Gamithromycin

Form

Injection

Species

Cattle Pigs Sheep

Manufacturer

Boehringer Ingelheim Vetmedica GmbH

VMD MA No.

EU/2/08/082/001-007

What it's used for

Cattle: Treatment and metaphylaxis of bovine respiratory disease (BRD) associated with Histophilus somni, Mannheimia haemolytica and Pasteurella multocida....

Full indications, dosage and side effects ↓

View official SPC (PDF)

The prescription itself has a price. See what practices near you charge for a consultation and the written prescription fee.

Paying less for Gamithromycin

1

Ask your vet for a written prescription

They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.
2

Fill it at a registered online retailer

The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

Your prescription rights → VMD register of retailers →

Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Zactran 150 mg/ml Solution for Injection for cattle, sheep and pigs — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

Cattle:
Treatment and metaphylaxis of bovine respiratory disease (BRD) associated with
Histophilus somni, Mannheimia haemolytica and Pasteurella multocida.
The presence of the disease in the group should be established before the product is
used.
Pigs:
Treatment of swine respiratory disease (SRD) associated with
pleuropneumoniae, Bordetella bronchiseptica, Glaesserella parasuis, and Pasteurella
multocida.

Revised: September 2024
AN: 02461/2023
Sheep:
Treatment of infectious pododermatitis (foot rot) associated with virulent
Dichelobacter nodosus and Fusobacterium necrophorum requiring systemic
treatment.

Do not use in cases of hypersensitivity to the active substance or to any of the
excipients or to other macrolide antibiotics.
Do not use this veterinary medicinal product simultaneously with other macrolides or
lincosamides (see section 4.8).

Cattle:
Very common
(>1 animal / 10 animals
treated)
Injection site swelling
, injection site pain
1
Typically resolves within 3 to 14 days but may persist for up to 35 days
Slight pain may develop for 1 day
Sheep:
Common
(1 to 10 animals / 100 animals
treated)
Injection site swelling
, injection site pain
3
Mild to moderate and typically resolves within 4 days
Slight pain may develop for 1 day
Pigs:
Common
(1 to 10 animals / 100 animals
treated)
Injection site swelling
5
Mild to moderate and typically resolves within 2 days
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder or its local representative or the national
competent authority via the national reporting system. See the package leaflet for
respective contact details.

Cattle, pigs and sheep:
Cross resistance has been shown between gamithromycin and other macrolides.
Use of the product should be carefully considered when susceptibility testing has
shown resistance to other macrolides because its effectiveness may be reduced.
Avoid simultaneous administration of antimicrobials with a similar mode of action
such as other macrolides or lincosamides.
Sheep:
The efficacy of antimicrobial treatment of foot rot might be reduced by other factors,
such as wet environmental conditions, as well as inappropriate farm management.
Treatment of foot rot should therefore be undertaken along with other flock
management tools, for example providing dry environment. Antibiotic treatment of
benign foot rot is not considered appropriate.

Special precautions for use in animals
Use of the product should be based on identification and susceptibility testing of the
target pathogen(s). If this is not possible, therapy should be based on
epidemiological information and knowledge of susceptibility of the target pathogens
at farm level, or at local/regional level. Use of the product should be in accordance
with official, national and regional antimicrobial policies.
An antibiotic with a lower risk of antimicrobial resistance selection (lower AMEG
category) should be used for first line treatment where susceptibility testing suggests
the likely efficacy of this approach.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals
People with known hypersensitivity to the macrolide class should avoid contact with
the veterinary medicinal product. Gamithromycin may cause irritation to eyes and/or
skin.
Avoid contact with skin or eyes. If eye exposure occurs, flush eyes immediately with
clean water. If skin exposure occurs, wash the affected area immediately with clean
water.

Revised: September 2024
AN: 02461/2023
In case of accidental self-injection, seek medical advice immediately and show the
package leaflet or the label to the physician.
Wash hands after use.
Special precautions for the protection of the environment:
Not applicable.
Other precautions
Not applicable.

See section 4.4.

This veterinary medicinal product does not require any special storage conditions.

Meat and offal:
Cattle: 64 days.
Sheep: 29 days.
Pigs: 16 days.
Not authorised for use in animals producing milk for human consumption.
Do not use in pregnant animals which are intended to produce milk for human
consumption within 2 months (cows, heifers) or 1 month (ewes) of expected
parturition.
5.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.