Skip to content
POM-V Prescription Required Companion Animal

Vanguard CPV-L

Active ingredients: Canine parvovirus, Leptospira canicola, Leptospira icterohaemorrhagiae

Form

Injection

Species

Dogs

Manufacturer

Zoetis UK Limited

VMD MA No.

42058/5180

What it's used for

Active immunisation of dogs to prevent clinical signs including leucopenia and reduce viral shedding caused by canine parvovirus (type 2a), to prevent mort...

Full indications, dosage and side effects ↓
View official SPC (PDF)

The prescription itself has a price. See what practices near you charge for a consultation and the written prescription fee.

Paying less for Canine parvovirus + Leptospi...

  1. 1

    Ask your vet for a written prescription

    They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.

  2. 2

    Fill it at a registered online retailer

    The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Vanguard CPV-L — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 26 Mar 2026.

Active immunisation of dogs to prevent clinical signs including leucopenia and reduce
viral shedding caused by canine parvovirus (type 2a), to prevent mortality and clinical
signs including leucopenia and reduce viral shedding caused by canine parvovirus
(types 2b and 2c), and to reduce clinical signs and infection due to Leptospira canicola
and Leptospira icterohaemorrhagiae.
Onset of immunity occurs by approximately two weeks after the last dose of the Basic
Vaccination Scheme. Onset of immunity for the canine parvovirus component (type 2b)
occurs 7 days after a single dose when animals are vaccinated from 9 weeks of age.
The duration of immunity is at least 12 months.

Revised: January 2025
AN: 02727/2024Page 2 of 5
Dosage and route of administration:
Shake well and immediately inject the entire contents of the vial (1 ml) subcutaneously.
Do not use chemically sterilised syringes or needles, as these will interfere with the
effectiveness of the vaccine.
Basic Vaccination Scheme:
Puppies younger than 10 weeks of age
Two doses of Vanguard CPV-L at least 14 days apart. The first dose can be given as
young as 7 weeks of age. The second dose should not be given until at least 10
weeks of age.
Puppies 10 weeks of age and older
A single dose of Vanguard CPV-L, followed by a single dose of Vanguard Lepto-ci at
least 14 days later
Re-vaccination Scheme:
A single dose of Vanguard CPV-L to be given annually thereafter
Do not use in unhealthy animals.
Vaccinated dogs may have a transient swelling 4-6 hours after vaccination which
resolves after approximately 7 days.
If a systemic anaphylactic reaction occurs (eg vomiting), administer adrenaline or an
equivalent.
The canine parvovirus vaccinal strains may be shed from vaccinated animals for a
number of days following vaccination. However, due to the low pathogenicity of this
strain, it is not necessary to keep vaccinated animals separated from non-vaccinated
animals.
High levels of maternally derived antibodies (MDA) may interfere with the response to
vaccination. Although the vaccine has been shown to be efficacious in the presence of
levels of MDA that are likely to be encountered under field conditions, where for any
reason it is likely that particularly high levels of MDA are present (for example against
the CPV component), this should be taken into account when planning the timing of
vaccinations.

i. Special precautions for use in animals
None
ii. Special precautions to be taken by the person administering the veterinary
medicinal product to animals
In case of accidental self-injection, wash the area immediately with water. If
symptoms develop, seek medical attention showing a copy of the product
literature.
No information is available on the safety and efficacy of this vaccine when used with
any other veterinary medicinal product, expect when used with vaccines from the
Vanguard range containing canine distemper virus, canine adenovirus or canine
parainfluenza virus. A decision to use this vaccine before or after any other veterinary
medicinal product therefore needs to be decided on a case by case basis.
Store and transport at +2°C to +8°C. Do not freeze.
Not applicable.
5. IMMUNOLOGICAL PROPERTIES
The vaccine is intended for the active immunisation of healthy puppies and dogs
against diseases caused by canine parvovirus, Leptospira canicola and Leptospira
icterohaemorrhagiae.
ATC vet code: QI07AI05

Revised: January 2025
AN: 02727/2024Page 4 of 5

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.

Medication costs adding up?

Pet insurance can cover prescription medications. Find the right policy for your pet.

Compare insurance

Find cheaper vets near you

Compare vet consultation prices in your area. Save on procedures and get a prescription to buy medications online.