Ubrolexin Intramammary Suspension for Lactating Dairy Cows
Active ingredients: Cefalexin, Kanamycin
Form
Intramammary
Species
Manufacturer
Boehringer Ingelheim Vetmedica GmbH
VMD MA No.
61700/5015
What it's used for
Pharmacodynamics Cefalexin is an antibacterial belonging to the group of antibiotics, and is structurally analogous to and has similar mode of action to pe...
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Paying less for Cefalexin + Kanamycin
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1
Ask your vet for a written prescription
They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.
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Fill it at a registered online retailer
The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.
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Prescription required
Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.
Ubrolexin Intramammary Suspension for Lactating Dairy Cows — SPC Details
Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.
Cefalexin is an antibacterial belonging to the group of antibiotics,
and is structurally analogous to and has similar mode of action to penicillins.
It belongs to the first generation of cephalosporins.
The β-lactam
inhibition of transpeptide and carboxypeptide enzymes, causing an osmotic
imbalance that destroys growing bacteria. Cefalexin is active against gram-
positive bacteria such as Staphylococcus aureus (including betalactamase-
producing strains), other staphylococci which do or do not produce penicillinases,
and
spp., including
Critical concentrations (cutting points or breakpoints) sensitivity (S) and
resistance (R), in µg/ml, for first generation cephalosporins (CLSI, 2013):
Susceptible: ≤≥ 32. The main mechanisms of
resistance against beta-lactams are the production of enzymes (beta-
lactamases) that inactivate the drug, the alteration of penicillin-fixing proteins and
the alteration of the permeability of the bacterial outer membrane. Cephalosporins
are generally not sensitive to the action of beta-lactamases.
There is a cross-resistance (involving the same resistance mechanism) between
antibiotics of the beta- lactam group due to structural similarities. It occurs with
beta-lactamase enzymes, structural changes in porins, or changes in efflux
pumps. Co-resistance (involving different resistance mechanisms) has been
described in E.coli due to the fact that a plasmid carries various genes encoding
resistance.
Use the contents of one syringe (containing 200 mg cefalexin as monohydrate and 100
000 I.U. kanamycin as monosulfate) per quarter per treatment. Each syringe is for single
use only.
Before infusion, the udder should be milked out completely, the teat should be
thoroughly cleaned and disinfected and care should be taken to avoid contamination
of the injector nozzle.
excipients.
Do not use in non-lactating cattle.
Do not use in the case of known resistance of cefalexin and/or kanamycin.
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder or the national competent authority via the
national reporting system. See the package leaflet for respective contact details.
Special precautions for safe use in the target species:
The veterinary medicinal product should be used for treatment of clinical mastitis
only.
Use of the product should be based on susceptibility testing of the bacteria isolated
from the animal. If this is not possible, therapy should be based on local (regional
and farm level) epidemiological information about susceptibility of the target bacteria
as well as by taking into account official national antimicrobial policies.
Inappropriate use of the veterinary medicinal product may increase the prevalence of
bacteria resistant to cefalexin and kanamycin and may decrease the effectiveness of
treatment with other cephalosporins or aminoglycosides due to the potential for
cross-resistance.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals:
Penicillins and cephalosporins may cause hypersensitivity (allergy) following
injection, inhalation, ingestion or skin contact. Hypersensitivity to penicillins may lead
to cross sensitivity to cephalosporin and vice versa. Allergic reactions to these
substances may occasionally be serious. People with known hypersensitivity to
cefalexin and kanamycin should avoid contact with the veterinary medicinal product.
Take all recommended precautions. Handle this veterinary medicinal product with
great care to avoid exposure by accidental contact with the skin. Personal protective
equipment consisting of gloves should be worn when handling the veterinary
medicinal product. Wash exposed skin after use.
If you develop symptoms following exposure, such as skin rash, you should seek
medical advice and show the package leaflet or the label to the physician. Swelling of
the face, lips and eyes or difficulty in breathing are more serious symptoms and
require urgent medical attention.
Special precautions for the protection of the environment:
Not applicable.
of resistance to cefalexin, cross-resistance with other cephalosporins is likely to
occur.
In case of resistance to kanamycin, cross-resistance occurs between kanamycin,
neomycin and paromomycin. A one-way resistance with streptomycin is known.
Milk: 5 days.
4.
This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.
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Other Products Containing Cefalexin
These products share the same active ingredient and may be suitable alternatives. Always consult your vet.
Cefabactin 1000 mg Tablets for Dogs
POM-VLe Vet Beheer B.V.
Cefabactin 1000 mg Tablets for Dogs
POM-VLe Vet Beheer B.V.
Cefabactin 250 mg Tablets for Dogs and Cats
POM-VLe Vet Beheer B.V.
Cefabactin 250 mg Tablets for Dogs and Cats
POM-VLe Vet Beheer B.V.
Cefabactin 50 mg Tablets for Dogs and Cats
POM-VLe Vet Beheer B.V.
Cefabactin 50 mg Tablets for Dogs and Cats
POM-VLe Vet Beheer B.V.
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